GB1101749A - Pharmacologically valuable n-substituted piperazines and compositions containing them - Google Patents
Pharmacologically valuable n-substituted piperazines and compositions containing themInfo
- Publication number
- GB1101749A GB1101749A GB2508264A GB2508264A GB1101749A GB 1101749 A GB1101749 A GB 1101749A GB 2508264 A GB2508264 A GB 2508264A GB 2508264 A GB2508264 A GB 2508264A GB 1101749 A GB1101749 A GB 1101749A
- Authority
- GB
- United Kingdom
- Prior art keywords
- piperazine
- thienyl
- reacting
- acyl
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004885 piperazines Chemical class 0.000 title abstract 3
- 239000000203 mixture Chemical class 0.000 title 1
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 7
- -1 N-substituted piperazines Chemical class 0.000 abstract 4
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Chemical group 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 3
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003826 tablet Substances 0.000 abstract 2
- KGRVJHAUYBGFFP-UHFFFAOYSA-N 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Chemical compound CC(C)(C)C1=CC(C)=CC(CC=2C(=C(C=C(C)C=2)C(C)(C)C)O)=C1O KGRVJHAUYBGFFP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- PCHPORCSPXIHLZ-UHFFFAOYSA-N diphenhydramine hydrochloride Chemical compound [Cl-].C=1C=CC=CC=1C(OCC[NH+](C)C)C1=CC=CC=C1 PCHPORCSPXIHLZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 239000006190 sub-lingual tablet Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL131191D NL131191C (enExample) | 1964-06-17 | ||
| GB2508264A GB1101749A (en) | 1964-06-17 | 1964-06-17 | Pharmacologically valuable n-substituted piperazines and compositions containing them |
| IL2372065A IL23720A (en) | 1964-06-17 | 1965-06-13 | Pharmacologically valuable piperazine derivatives and compositions containing them |
| BE665441D BE665441A (enExample) | 1964-06-17 | 1965-06-15 | |
| BR17044165A BR6570441D0 (pt) | 1964-06-17 | 1965-06-16 | Processo para preparar uma composicao farmaceutica contendo uma n-alcoilpiperazina |
| FR21075A FR4943M (enExample) | 1964-06-17 | 1965-06-16 | |
| ES0314285A ES314285A1 (es) | 1964-06-17 | 1965-06-16 | Metodo para preparar composiciones que contienen una n-alquil-piperacina |
| NL6507758A NL6507758A (enExample) | 1964-06-17 | 1965-06-17 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2508264A GB1101749A (en) | 1964-06-17 | 1964-06-17 | Pharmacologically valuable n-substituted piperazines and compositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1101749A true GB1101749A (en) | 1968-01-31 |
Family
ID=10221910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2508264A Expired GB1101749A (en) | 1964-06-17 | 1964-06-17 | Pharmacologically valuable n-substituted piperazines and compositions containing them |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE665441A (enExample) |
| BR (1) | BR6570441D0 (enExample) |
| ES (1) | ES314285A1 (enExample) |
| FR (1) | FR4943M (enExample) |
| GB (1) | GB1101749A (enExample) |
| IL (1) | IL23720A (enExample) |
| NL (2) | NL6507758A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7238688B2 (en) * | 2001-03-13 | 2007-07-03 | Schering Corporation | Piperidine compounds |
-
0
- NL NL131191D patent/NL131191C/xx active
-
1964
- 1964-06-17 GB GB2508264A patent/GB1101749A/en not_active Expired
-
1965
- 1965-06-13 IL IL2372065A patent/IL23720A/xx unknown
- 1965-06-15 BE BE665441D patent/BE665441A/xx unknown
- 1965-06-16 FR FR21075A patent/FR4943M/fr not_active Expired
- 1965-06-16 BR BR17044165A patent/BR6570441D0/pt unknown
- 1965-06-16 ES ES0314285A patent/ES314285A1/es not_active Expired
- 1965-06-17 NL NL6507758A patent/NL6507758A/xx unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7238688B2 (en) * | 2001-03-13 | 2007-07-03 | Schering Corporation | Piperidine compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| BR6570441D0 (pt) | 1973-08-14 |
| NL131191C (enExample) | |
| IL23720A (en) | 1969-03-27 |
| ES314285A1 (es) | 1966-05-01 |
| BE665441A (enExample) | 1965-12-15 |
| FR4943M (enExample) | 1967-03-28 |
| NL6507758A (enExample) | 1965-12-20 |
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