GB1087876A - Pteridine derivatives - Google Patents

Pteridine derivatives

Info

Publication number
GB1087876A
GB1087876A GB13529/67A GB1352967A GB1087876A GB 1087876 A GB1087876 A GB 1087876A GB 13529/67 A GB13529/67 A GB 13529/67A GB 1352967 A GB1352967 A GB 1352967A GB 1087876 A GB1087876 A GB 1087876A
Authority
GB
United Kingdom
Prior art keywords
compounds
pteridine derivatives
benzyl
alkyl
benzylsulphonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB13529/67A
Other languages
English (en)
Inventor
Edward Jethro Cragoe Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1087876A publication Critical patent/GB1087876A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB13529/67A 1962-10-30 1964-10-06 Pteridine derivatives Expired GB1087876A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23423062A 1962-10-30 1962-10-30
US35604064A 1964-03-31 1964-03-31
US534638A US3360517A (en) 1962-10-30 1966-03-16 3-amino-6-substituted-pyrazinoyl-guanidines

Publications (1)

Publication Number Publication Date
GB1087876A true GB1087876A (en) 1967-10-18

Family

ID=26999095

Family Applications (2)

Application Number Title Priority Date Filing Date
GB13529/67A Expired GB1087876A (en) 1962-10-30 1964-10-06 Pteridine derivatives
GB40717/64A Expired GB1087875A (en) 1962-10-30 1964-10-06 Pyrazinoylguanidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB40717/64A Expired GB1087875A (en) 1962-10-30 1964-10-06 Pyrazinoylguanidines

Country Status (6)

Country Link
US (1) US3360517A (enExample)
BE (1) BE653479A (enExample)
DE (1) DE1470088A1 (enExample)
FR (1) FR95455E (enExample)
GB (2) GB1087876A (enExample)
NL (1) NL6409714A (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3531484A (en) * 1968-02-14 1970-09-29 Merck & Co Inc 1-(3-aminopyrazinoyl)-4,5,5-trisubstituted biguanide products
US4140776A (en) * 1977-09-16 1979-02-20 Merck & Co., Inc. N-pyrazinecarbonyl-N'-acylguanidines
US4246406A (en) * 1979-03-27 1981-01-20 Merck & Co., Inc. Heterocyclic substituted pyrazinoylguanidines
US5681903A (en) * 1995-12-20 1997-10-28 Shell Oil Company Process for the preparation of polymeric alpha, omega-dialdehydes and diacids
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
EP3150585A1 (en) 2012-12-17 2017-04-05 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
WO2016207345A1 (en) * 2015-06-24 2016-12-29 Pierre Fabre Medicament 3-amino-pyrazin-2-yl carboxamide and 2-amino-pyridin-3-yl carboxamide derivatives as polo-like kinase 1 (plk-1) inhibitors for the treatment of cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL299931A (enExample) * 1962-10-30

Also Published As

Publication number Publication date
FR95455E (fr) 1971-01-15
BE653479A (enExample) 1965-03-23
GB1087875A (en) 1967-10-18
NL6409714A (enExample) 1965-10-01
DE1470088A1 (de) 1969-07-10
US3360517A (en) 1967-12-26

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