GB1087876A - Pteridine derivatives - Google Patents
Pteridine derivativesInfo
- Publication number
- GB1087876A GB1087876A GB13529/67A GB1352967A GB1087876A GB 1087876 A GB1087876 A GB 1087876A GB 13529/67 A GB13529/67 A GB 13529/67A GB 1352967 A GB1352967 A GB 1352967A GB 1087876 A GB1087876 A GB 1087876A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- pteridine derivatives
- benzyl
- alkyl
- benzylsulphonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000001042 pteridinyl group Chemical class N1=C(N=CC2=NC=CN=C12)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 benzyl-thio Chemical group 0.000 abstract 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23423062A | 1962-10-30 | 1962-10-30 | |
| US35604064A | 1964-03-31 | 1964-03-31 | |
| US534638A US3360517A (en) | 1962-10-30 | 1966-03-16 | 3-amino-6-substituted-pyrazinoyl-guanidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1087876A true GB1087876A (en) | 1967-10-18 |
Family
ID=26999095
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13529/67A Expired GB1087876A (en) | 1962-10-30 | 1964-10-06 | Pteridine derivatives |
| GB40717/64A Expired GB1087875A (en) | 1962-10-30 | 1964-10-06 | Pyrazinoylguanidines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB40717/64A Expired GB1087875A (en) | 1962-10-30 | 1964-10-06 | Pyrazinoylguanidines |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3360517A (en:Method) |
| BE (1) | BE653479A (en:Method) |
| DE (1) | DE1470088A1 (en:Method) |
| FR (1) | FR95455E (en:Method) |
| GB (2) | GB1087876A (en:Method) |
| NL (1) | NL6409714A (en:Method) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3531484A (en) * | 1968-02-14 | 1970-09-29 | Merck & Co Inc | 1-(3-aminopyrazinoyl)-4,5,5-trisubstituted biguanide products |
| US4140776A (en) * | 1977-09-16 | 1979-02-20 | Merck & Co., Inc. | N-pyrazinecarbonyl-N'-acylguanidines |
| US4246406A (en) * | 1979-03-27 | 1981-01-20 | Merck & Co., Inc. | Heterocyclic substituted pyrazinoylguanidines |
| US5681903A (en) * | 1995-12-20 | 1997-10-28 | Shell Oil Company | Process for the preparation of polymeric alpha, omega-dialdehydes and diacids |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7745442B2 (en) | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| AU2013363218B2 (en) | 2012-12-17 | 2018-03-15 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration |
| RU2018138195A (ru) | 2012-12-17 | 2018-12-18 | Пэрион Сайенсиз, Инк. | Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
| WO2016207345A1 (en) * | 2015-06-24 | 2016-12-29 | Pierre Fabre Medicament | 3-amino-pyrazin-2-yl carboxamide and 2-amino-pyridin-3-yl carboxamide derivatives as polo-like kinase 1 (plk-1) inhibitors for the treatment of cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL299931A (en:Method) * | 1962-10-30 |
-
1964
- 1964-08-21 NL NL6409714A patent/NL6409714A/xx unknown
- 1964-08-25 FR FR986157A patent/FR95455E/fr not_active Expired
- 1964-08-28 DE DE19641470088 patent/DE1470088A1/de active Pending
- 1964-09-23 BE BE653479D patent/BE653479A/xx unknown
- 1964-10-06 GB GB13529/67A patent/GB1087876A/en not_active Expired
- 1964-10-06 GB GB40717/64A patent/GB1087875A/en not_active Expired
-
1966
- 1966-03-16 US US534638A patent/US3360517A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NL6409714A (en:Method) | 1965-10-01 |
| BE653479A (en:Method) | 1965-03-23 |
| US3360517A (en) | 1967-12-26 |
| GB1087875A (en) | 1967-10-18 |
| DE1470088A1 (de) | 1969-07-10 |
| FR95455E (fr) | 1971-01-15 |
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