GB1058694A - Nitrofuran derivatives - Google Patents

Nitrofuran derivatives

Info

Publication number
GB1058694A
GB1058694A GB3865363A GB3865363A GB1058694A GB 1058694 A GB1058694 A GB 1058694A GB 3865363 A GB3865363 A GB 3865363A GB 3865363 A GB3865363 A GB 3865363A GB 1058694 A GB1058694 A GB 1058694A
Authority
GB
United Kingdom
Prior art keywords
formula
inorganic acid
hydrogen atom
compounds
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3865363A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB1058694A publication Critical patent/GB1058694A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70—Nitro radicals
    • C07D307/71—Nitro radicals attached in position 5
    • C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
    • C07D307/74—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals
    • C07D307/76—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals having carbonic acyl radicals or their thio or nitrogen analogues directly attached to the hydrazino or hydrazono radical, e.g. semicarbazides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention comprises compounds of the formula <FORM:1058694/C2/1> in which R is a hydrogen or halogen atom or an alkyl group, R1 is a hydrogen atom or an alkyl, aryl or aralkyl group and R11 is a hydrogen atom or an acyl group; inorganic acid addition salts; and a process for their preparation comprising cyclizing a thiosemicarbazone of the formula <FORM:1058694/C2/2> by heating it in water with ferric chloride and, if desired, reacting the product with an inorganic acid to form the corresponding inorganic acid addition salt. The compounds in which R11 is an acyl group may also be prepared by acylating the corresponding compounds in which R11 is a hydrogen atom. Thiosemicarbazones of the Formula II are prepared by reacting a thiosemicarbazide of the formula <FORM:1058694/C2/3> with a substituted acrolein of the formula <FORM:1058694/C2/4>
GB3865363A 1962-10-05 1963-10-01 Nitrofuran derivatives Expired GB1058694A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4306462 1962-10-05
JP3050263 1963-06-14

Publications (1)

Publication Number Publication Date
GB1058694A true GB1058694A (en) 1967-02-15

Family

ID=26368873

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3865363A Expired GB1058694A (en) 1962-10-05 1963-10-01 Nitrofuran derivatives

Country Status (6)

Country Link
BE (1) BE638221A (en)
CH (1) CH440295A (en)
DE (1) DE1470048C3 (en)
ES (1) ES292202A1 (en)
FR (1) FR1604111A (en)
GB (1) GB1058694A (en)

Also Published As

Publication number Publication date
DE1470048B2 (en) 1974-03-21
FR1604111A (en) 1971-07-12
BE638221A (en)
DE1470048A1 (en) 1972-05-10
CH440295A (en) 1967-07-31
DE1470048C3 (en) 1974-11-07
ES292202A1 (en) 1964-01-16

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