GB1054655A - - Google Patents
Info
- Publication number
- GB1054655A GB1054655A GB1054655DA GB1054655A GB 1054655 A GB1054655 A GB 1054655A GB 1054655D A GB1054655D A GB 1054655DA GB 1054655 A GB1054655 A GB 1054655A
- Authority
- GB
- United Kingdom
- Prior art keywords
- stands
- radicals
- acid addition
- radical
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- -1 alkyl radical Chemical class 0.000 abstract 8
- 150000001875 compounds Chemical class 0.000 abstract 8
- 125000005843 halogen group Chemical group 0.000 abstract 7
- 239000002253 acid Substances 0.000 abstract 6
- 150000003839 salts Chemical class 0.000 abstract 6
- 150000005840 aryl radicals Chemical class 0.000 abstract 5
- 150000003254 radicals Chemical class 0.000 abstract 5
- 125000004104 aryloxy group Chemical group 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- CMRFFANZXZJIEU-UHFFFAOYSA-N 2-bromo-1-(3,4-dihydro-2H-chromen-2-yl)ethanol Chemical compound BrCC(O)C1OC2=CC=CC=C2CC1 CMRFFANZXZJIEU-UHFFFAOYSA-N 0.000 abstract 1
- HPTKNVTUACARLC-UHFFFAOYSA-N 2-bromo-1-(3,4-dihydro-2h-chromen-2-yl)ethanone Chemical compound C1=CC=C2OC(C(=O)CBr)CCC2=C1 HPTKNVTUACARLC-UHFFFAOYSA-N 0.000 abstract 1
- PTSVVJYZYOFHAM-UHFFFAOYSA-N 2-chloro-1-(2,3-dihydro-1-benzofuran-2-yl)ethanol Chemical compound OC(CCl)C1CC2=C(O1)C=CC=C2 PTSVVJYZYOFHAM-UHFFFAOYSA-N 0.000 abstract 1
- SIERJJOFHQYJIA-UHFFFAOYSA-N 2-chloro-1-(2,3-dihydro-1-benzofuran-2-yl)ethanone Chemical compound C1=CC=C2OC(C(=O)CCl)CC2=C1 SIERJJOFHQYJIA-UHFFFAOYSA-N 0.000 abstract 1
- BARYGNGWKGZTDL-UHFFFAOYSA-N 2-chloro-1-(3,4-dihydro-2H-chromen-2-yl)ethanol Chemical compound ClCC(O)C1OC2=CC=CC=C2CC1 BARYGNGWKGZTDL-UHFFFAOYSA-N 0.000 abstract 1
- NFPQVHVIHCVMHJ-UHFFFAOYSA-N 2-chloro-1-(3,4-dihydro-2H-chromen-2-yl)ethanone Chemical compound ClCC(=O)C1OC2=CC=CC=C2CC1 NFPQVHVIHCVMHJ-UHFFFAOYSA-N 0.000 abstract 1
- FLYPCJLLVUMPEC-UHFFFAOYSA-N 2-diazo-1-(2,3-dihydro-1-benzofuran-2-yl)ethanone Chemical compound [N+](=[N-])=CC(=O)C1OC2=C(C1)C=CC=C2 FLYPCJLLVUMPEC-UHFFFAOYSA-N 0.000 abstract 1
- UXOHRZNOVPCNMD-UHFFFAOYSA-N 3,4-dihydro-2h-chromene-2-carbonyl chloride Chemical compound C1=CC=C2OC(C(=O)Cl)CCC2=C1 UXOHRZNOVPCNMD-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000006179 O-acylation Effects 0.000 abstract 1
- CRXFCQCGOLSXQE-UHFFFAOYSA-N O.O1C(CCC2=CC=CC=C12)C(C=O)=O Chemical compound O.O1C(CCC2=CC=CC=C12)C(C=O)=O CRXFCQCGOLSXQE-UHFFFAOYSA-N 0.000 abstract 1
- 230000001800 adrenalinergic effect Effects 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB320164 | 1964-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1054655A true GB1054655A (en, 2012) |
Family
ID=9753863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1054655D Active GB1054655A (en, 2012) | 1964-01-24 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3371100A (en, 2012) |
| BE (1) | BE658740A (en, 2012) |
| CH (1) | CH461526A (en, 2012) |
| DE (1) | DE1493863A1 (en, 2012) |
| DK (4) | DK107753C (en, 2012) |
| FR (2) | FR1584954A (en, 2012) |
| GB (1) | GB1054655A (en, 2012) |
| NL (1) | NL6500863A (en, 2012) |
| SE (1) | SE324159B (en, 2012) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0145067A3 (en) * | 1983-12-05 | 1986-03-26 | Janssen Pharmaceutica N.V. | Derivatives of 2,2'-iminobisethanol |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3929836A (en) * | 1965-05-11 | 1975-12-30 | Hoffmann La Roche | 2-(2-Lower alkylamino-1-hydroxy-ethyl)-substituted benzofurans |
| FR2353291A1 (fr) * | 1976-05-31 | 1977-12-30 | Parcor | Nouveaux derives du benzofuranne |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL291944A (en, 2012) * | 1960-05-04 | |||
| GB1019225A (en) * | 1962-10-23 | 1966-02-02 | Ici Ltd | Aminoethanol derivatives |
| GB1038333A (en) * | 1963-02-13 | 1966-08-10 | Ici Ltd | Pharmaceutical compositions |
| US3255249A (en) * | 1963-04-26 | 1966-06-07 | Ici Ltd | 2-branched lower alkyl-amino-1-(indan-, hydrogenated indan- and hydrogenated naphth-2-yl) lower alkanols |
-
0
- GB GB1054655D patent/GB1054655A/en active Active
-
1965
- 1965-01-05 US US423594A patent/US3371100A/en not_active Expired - Lifetime
- 1965-01-20 SE SE739/65A patent/SE324159B/xx unknown
- 1965-01-20 DE DE19651493863 patent/DE1493863A1/de active Pending
- 1965-01-22 NL NL6500863A patent/NL6500863A/xx unknown
- 1965-01-22 BE BE658740A patent/BE658740A/xx unknown
- 1965-01-22 FR FR1584954D patent/FR1584954A/fr not_active Expired
- 1965-01-25 DK DK75666AA patent/DK107753C/da active
- 1965-01-25 DK DK75566AA patent/DK108283C/da active
- 1965-01-25 DK DK39965AA patent/DK107487C/da active
- 1965-01-25 CH CH100165A patent/CH461526A/de unknown
- 1965-04-21 FR FR14090A patent/FR4660M/fr not_active Expired
-
1966
- 1966-02-14 DK DK75766AA patent/DK111074B/da unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0145067A3 (en) * | 1983-12-05 | 1986-03-26 | Janssen Pharmaceutica N.V. | Derivatives of 2,2'-iminobisethanol |
Also Published As
| Publication number | Publication date |
|---|---|
| FR1584954A (en, 2012) | 1970-01-09 |
| DK108283C (da) | 1967-11-06 |
| DK111074B (da) | 1968-05-27 |
| BE658740A (en, 2012) | 1965-07-22 |
| NL6500863A (en, 2012) | 1965-07-26 |
| SE324159B (en, 2012) | 1970-05-25 |
| DE1493863A1 (de) | 1969-09-11 |
| DK107487C (da) | 1967-06-05 |
| US3371100A (en) | 1968-02-27 |
| DK107753C (da) | 1967-07-03 |
| FR4660M (en, 2012) | 1966-12-12 |
| CH461526A (de) | 1968-08-31 |
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