GB1053504A - - Google Patents

Info

Publication number
GB1053504A
GB1053504A GB873165A GB873165A GB1053504A GB 1053504 A GB1053504 A GB 1053504A GB 873165 A GB873165 A GB 873165A GB 873165 A GB873165 A GB 873165A GB 1053504 A GB1053504 A GB 1053504A
Authority
GB
United Kingdom
Prior art keywords
particles
march
cardiolipin
antigen
choline chloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB873165A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GB1053504A publication Critical patent/GB1053504A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

1,053,504. Diagnostic composition for syphilis test. CHAS. PFIZER & CO. Inc. March 1, 1965 [March 17, 1964], No. 8731/65. Heading B1X. A diagnostic composition which gives an agglutination reaction with syphilitic blood serum comprises an aqueous suspension containing 0.1-3% of 0.3-2.0Á polystyrene particles coated with cardiolipin antigen, and 4-6% w/v of choline chloride. The antigen is derived from an ethanolic solution containing 0.03% cardiolipin, 0.9% cholestrol and 0.2% lecithin. The preferred medium is 0.85% saline containing 0.01% MgSO 4 . First the particles may be coated by mixing a suspension of latex in saline with said ethanolic solution, centrifuging, decanting off the supernatant liquid and resuspending the remaining particles in a solution of choline chloride.
GB873165A 1964-03-17 1965-03-01 Expired GB1053504A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35264264A 1964-03-17 1964-03-17

Publications (1)

Publication Number Publication Date
GB1053504A true GB1053504A (en) 1967-01-04

Family

ID=23385912

Family Applications (1)

Application Number Title Priority Date Filing Date
GB873165A Expired GB1053504A (en) 1964-03-17 1965-03-01

Country Status (4)

Country Link
BR (1) BR6567756D0 (en)
DE (1) DE1280585B (en)
FR (1) FR1455067A (en)
GB (1) GB1053504A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000075666A1 (en) * 1999-06-09 2000-12-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method for detecting syphilis using synthetic antigens
US6815173B1 (en) 1999-06-09 2004-11-09 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting syphilis using synthetic antigents

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1086225A (en) * 1976-03-18 1980-09-23 Masuo Aizawa Syphilis antibody diagnosis by antigen membrane and potentiometric method
US4738932A (en) * 1985-12-03 1988-04-19 Advanced Polymer Systems, Inc. Reaginic test for syphilis

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000075666A1 (en) * 1999-06-09 2000-12-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Method for detecting syphilis using synthetic antigens
AU771548B2 (en) * 1999-06-09 2004-03-25 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method for detecting syphilis using synthetic antigens
US6815173B1 (en) 1999-06-09 2004-11-09 The United States Of America As Represented By The Department Of Health And Human Services Method for detecting syphilis using synthetic antigents
USRE43914E1 (en) 1999-06-09 2013-01-08 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Method for detecting syphilis using synthetic antigens

Also Published As

Publication number Publication date
FR1455067A (en) 1966-10-14
DE1280585B (en) 1968-10-17
BR6567756D0 (en) 1973-07-26

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