GB1048027A - Pregneno and pregnadieno[3,2-c]pyrazoles - Google Patents

Pregneno and pregnadieno[3,2-c]pyrazoles

Info

Publication number
GB1048027A
GB1048027A GB21484/63A GB2148463A GB1048027A GB 1048027 A GB1048027 A GB 1048027A GB 21484/63 A GB21484/63 A GB 21484/63A GB 2148463 A GB2148463 A GB 2148463A GB 1048027 A GB1048027 A GB 1048027A
Authority
GB
United Kingdom
Prior art keywords
fluoro
acetoxy
hydroxy
pregnadien
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB21484/63A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1048027A publication Critical patent/GB1048027A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0042—Nitrogen only
    • C07J71/0047—Nitrogen only at position 2(3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB21484/63A 1962-06-20 1963-05-29 Pregneno and pregnadieno[3,2-c]pyrazoles Expired GB1048027A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US203713A US3116287A (en) 1962-06-20 1962-06-20 Delta and delta1,4 derivatives of 16alpha-fluorosteroid-[3, 2-c] pyrazoles of the pregnane series

Publications (1)

Publication Number Publication Date
GB1048027A true GB1048027A (en) 1966-11-09

Family

ID=22755017

Family Applications (1)

Application Number Title Priority Date Filing Date
GB21484/63A Expired GB1048027A (en) 1962-06-20 1963-05-29 Pregneno and pregnadieno[3,2-c]pyrazoles

Country Status (6)

Country Link
US (1) US3116287A (enExample)
BE (1) BE633907A (enExample)
BR (1) BR6349812D0 (enExample)
FR (1) FR1552756A (enExample)
GB (1) GB1048027A (enExample)
NL (1) NL294349A (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH491888A (de) * 1967-09-04 1970-06-15 Ciba Geigy Neues Verfahren zur Herstellung von 17a,20;20,21-Bis-methylendioxy-steroiden
CN116023425B (zh) * 2023-03-28 2023-06-20 南京师范大学 曲安西龙衍生物及其医药用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2945852A (en) * 1959-05-20 1960-07-19 Searle & Co 17-oxygenated 9alpha-substituted androstano [3, 2-c] pyrazoles and derivatives

Also Published As

Publication number Publication date
FR1552756A (enExample) 1969-01-10
BR6349812D0 (pt) 1973-07-03
US3116287A (en) 1963-12-31
NL294349A (enExample)
BE633907A (enExample)

Similar Documents

Publication Publication Date Title
US2541104A (en) 17(alpha)-hydroxy-20-ketosteroids and process
GB1048027A (en) Pregneno and pregnadieno[3,2-c]pyrazoles
US3026317A (en) [3, 2-c]-pyrimidine derivatives of androstane compounds
US3471477A (en) 6-gem-difluoro (3,2-c) and (2,3-d) pyrazole steroids
US3067194A (en) 4, 6-pregnadieno-[3, 2-c] pyrazoles and processes of preparing them
US2735854A (en) Steroid compounds
US3055922A (en) 16-methyl-17alpha-hydroxy-3, 20-diketopregnanes
US3032552A (en) 1-methyl steroids of the androstane series
US3384645A (en) 7-methylene-3alpha, 5-cyclo-6-ketone steroids and process for producing same
US3076823A (en) Process for the production of 6-chloro-3-keto-deta steroid compounds
US3332941A (en) 17-ether compounds of 17beta-hydroxy-5alpha-androstano[2, 3-c] furazan
US3178412A (en) Process for the production of 6beta-fluoro steroids
US2842571A (en) Method of obtaining steroid hormone derivatives substituted in the 4-position
US3211761A (en) New 19-hydroxy-steroids
US3148183A (en) Delta4 and delta4, 6-17alpha-acyloxy-20-oxo-steroid-[3, 2-c] pyrazoles of the pregnane series
US3300483A (en) 4, 6-pregnadieno-[3, 2-c] pyrazoles and processes of preparing them
US3474091A (en) 3-cyanomethylene-pregnenes and their manufacture and use
GB817176A (en) Improvements in or relating to cyclopentanophenanthrene compounds
US3403148A (en) Process for the manufacture of 3-oxo-7alpha-methyl-17-ethylene-dioxy-delta1, 4-androstadiene
US2857406A (en) Derivatives of cortical hormones
GB1152180A (en) delta<8(14)>-Steroids
US2838550A (en) 11 alpha-hydroxy-4, 16-pregnadiene-3, 20-dione and esters
US3290298A (en) The lactone of 3'-[4-fluoro-4-androstene-17-ol-3-one-17-yl]-propionic acid and process utilized in the preparation thereof
US3330824A (en) 3-lower alkoxy estra-1, 3, 5(10) triene-[17, 16-c]-pyrazoles
GB805830A (en) Steroid compounds