GB1044572A - Pharmaceutical preparations in sustained release form - Google Patents
Pharmaceutical preparations in sustained release formInfo
- Publication number
- GB1044572A GB1044572A GB8960/64A GB896064A GB1044572A GB 1044572 A GB1044572 A GB 1044572A GB 8960/64 A GB8960/64 A GB 8960/64A GB 896064 A GB896064 A GB 896064A GB 1044572 A GB1044572 A GB 1044572A
- Authority
- GB
- United Kingdom
- Prior art keywords
- fatty acid
- inert
- sustained release
- coating
- pellets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000012730 sustained-release form Substances 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000011248 coating agent Substances 0.000 abstract 4
- 238000000576 coating method Methods 0.000 abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 4
- 239000000194 fatty acid Substances 0.000 abstract 4
- 229930195729 fatty acid Natural products 0.000 abstract 4
- 150000004665 fatty acids Chemical class 0.000 abstract 4
- 239000000843 powder Substances 0.000 abstract 4
- -1 C22 saturated fatty acids Chemical class 0.000 abstract 3
- FTOAOBMCPZCFFF-UHFFFAOYSA-N 5,5-diethylbarbituric acid Chemical compound CCC1(CC)C(=O)NC(=O)NC1=O FTOAOBMCPZCFFF-UHFFFAOYSA-N 0.000 abstract 2
- RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- VIROVYVQCGLCII-UHFFFAOYSA-N amobarbital Chemical compound CC(C)CCC1(CC)C(=O)NC(=O)NC1=O VIROVYVQCGLCII-UHFFFAOYSA-N 0.000 abstract 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 2
- 238000010410 dusting Methods 0.000 abstract 2
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 239000008188 pellet Substances 0.000 abstract 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 abstract 2
- 238000013268 sustained release Methods 0.000 abstract 2
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 abstract 1
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 abstract 1
- RKUNBYITZUJHSG-FXUDXRNXSA-N (S)-atropine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@H]3CC[C@@H](C2)N3C)=CC=CC=C1 RKUNBYITZUJHSG-FXUDXRNXSA-N 0.000 abstract 1
- FUFLCEKSBBHCMO-UHFFFAOYSA-N 11-dehydrocorticosterone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 FUFLCEKSBBHCMO-UHFFFAOYSA-N 0.000 abstract 1
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 abstract 1
- 239000005995 Aluminium silicate Substances 0.000 abstract 1
- 229930003347 Atropine Natural products 0.000 abstract 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 abstract 1
- 239000004099 Chlortetracycline Substances 0.000 abstract 1
- MFYSYFVPBJMHGN-ZPOLXVRWSA-N Cortisone Chemical compound O=C1CC[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 MFYSYFVPBJMHGN-ZPOLXVRWSA-N 0.000 abstract 1
- MFYSYFVPBJMHGN-UHFFFAOYSA-N Cortisone Natural products O=C1CCC2(C)C3C(=O)CC(C)(C(CC4)(O)C(=O)CO)C4C3CCC2=C1 MFYSYFVPBJMHGN-UHFFFAOYSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 abstract 1
- 239000005909 Kieselgur Substances 0.000 abstract 1
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 239000000150 Sympathomimetic Substances 0.000 abstract 1
- 239000004098 Tetracycline Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 235000012211 aluminium silicate Nutrition 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- KRMDCWKBEZIMAB-UHFFFAOYSA-N amitriptyline Chemical compound C1CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 KRMDCWKBEZIMAB-UHFFFAOYSA-N 0.000 abstract 1
- 229960000836 amitriptyline Drugs 0.000 abstract 1
- 229960001301 amobarbital Drugs 0.000 abstract 1
- 229940025084 amphetamine Drugs 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229940125715 antihistaminic agent Drugs 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003434 antitussive agent Substances 0.000 abstract 1
- 229940124584 antitussives Drugs 0.000 abstract 1
- 229960000396 atropine Drugs 0.000 abstract 1
- RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 abstract 1
- 229960002319 barbital Drugs 0.000 abstract 1
- 229940125717 barbiturate Drugs 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 239000000168 bronchodilator agent Substances 0.000 abstract 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
- SOYKEARSMXGVTM-UHFFFAOYSA-N chlorphenamine Chemical compound C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 SOYKEARSMXGVTM-UHFFFAOYSA-N 0.000 abstract 1
- 229960003291 chlorphenamine Drugs 0.000 abstract 1
- 229960004475 chlortetracycline Drugs 0.000 abstract 1
- CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 abstract 1
- 235000019365 chlortetracycline Nutrition 0.000 abstract 1
- 229960004126 codeine Drugs 0.000 abstract 1
- 229960004544 cortisone Drugs 0.000 abstract 1
- JJCFRYNCJDLXIK-UHFFFAOYSA-N cyproheptadine Chemical compound C1CN(C)CCC1=C1C2=CC=CC=C2C=CC2=CC=CC=C21 JJCFRYNCJDLXIK-UHFFFAOYSA-N 0.000 abstract 1
- 229960001140 cyproheptadine Drugs 0.000 abstract 1
- 229960003957 dexamethasone Drugs 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 229940030606 diuretics Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 1
- 229960000890 hydrocortisone Drugs 0.000 abstract 1
- 229960003210 hyoscyamine Drugs 0.000 abstract 1
- 229930005342 hyoscyamine Natural products 0.000 abstract 1
- 229940039009 isoproterenol Drugs 0.000 abstract 1
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 abstract 1
- 229960002695 phenobarbital Drugs 0.000 abstract 1
- 229960005205 prednisolone Drugs 0.000 abstract 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 abstract 1
- 235000003441 saturated fatty acids Nutrition 0.000 abstract 1
- 229960002646 scopolamine Drugs 0.000 abstract 1
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 229960005322 streptomycin Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 230000001975 sympathomimetic effect Effects 0.000 abstract 1
- 229940064707 sympathomimetics Drugs 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- 229960002180 tetracycline Drugs 0.000 abstract 1
- 229930101283 tetracycline Natural products 0.000 abstract 1
- 235000019364 tetracycline Nutrition 0.000 abstract 1
- 150000003522 tetracyclines Chemical class 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26237363A | 1963-03-04 | 1963-03-04 | |
| US339911A US3383283A (en) | 1964-01-24 | 1964-01-24 | Medicinal pellets coated with overlapping porous fatty acid leaflet layers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1044572A true GB1044572A (en) | 1966-10-05 |
Family
ID=26949172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB8960/64A Expired GB1044572A (en) | 1963-03-04 | 1964-03-03 | Pharmaceutical preparations in sustained release form |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE644643A (enrdf_load_stackoverflow) |
| BR (1) | BR6457270D0 (enrdf_load_stackoverflow) |
| ES (1) | ES297425A1 (enrdf_load_stackoverflow) |
| FR (1) | FR4731M (enrdf_load_stackoverflow) |
| GB (1) | GB1044572A (enrdf_load_stackoverflow) |
| NL (1) | NL6402159A (enrdf_load_stackoverflow) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2401618A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants et composition d'enrobage pour ces granules |
| FR2401620A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants |
| DE3721721C1 (de) * | 1987-07-01 | 1988-06-09 | Hoechst Ag | Verfahren zur Umhuellung von Granulaten |
| US4834985A (en) * | 1986-06-05 | 1989-05-30 | Euroceltique S.A. | Controlled release pharmaceutical composition |
| US5008118A (en) * | 1987-06-23 | 1991-04-16 | Nippon Oil And Fats | Method for producing organic agent coated with powders of coating agent |
| US5149542A (en) * | 1986-09-30 | 1992-09-22 | Roberto Valducci | Coating membrane and compositions prepared therefrom |
| US5662935A (en) * | 1992-12-23 | 1997-09-02 | Saitec S.R.L. | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
| US5707636A (en) * | 1994-08-03 | 1998-01-13 | Saitec S.R.L. | Apparatus and method for preparing solid forms with controlled release of the active ingredient |
| EP1872779A1 (de) * | 2006-06-28 | 2008-01-02 | Oramon Arzneimittel GmbH | Stabile multipartikuläre pharmazeutische Zusammensetzung von tri- und tetracyclischen Antidepressiva |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2849437B2 (ja) * | 1990-03-30 | 1999-01-20 | 東陽化成株式会社 | 乳化状の化粧品と医薬部外品 |
-
1964
- 1964-03-03 ES ES297425A patent/ES297425A1/es not_active Expired
- 1964-03-03 BE BE644643D patent/BE644643A/xx unknown
- 1964-03-03 BR BR15727064A patent/BR6457270D0/pt unknown
- 1964-03-03 GB GB8960/64A patent/GB1044572A/en not_active Expired
- 1964-03-04 NL NL6402159A patent/NL6402159A/xx unknown
- 1964-05-20 FR FR975158A patent/FR4731M/fr not_active Expired
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2401618A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants et composition d'enrobage pour ces granules |
| FR2401620A1 (fr) * | 1977-09-02 | 1979-03-30 | Eastman Kodak Co | Granules indegradables dans la panse des ruminants |
| US4834985A (en) * | 1986-06-05 | 1989-05-30 | Euroceltique S.A. | Controlled release pharmaceutical composition |
| US5149542A (en) * | 1986-09-30 | 1992-09-22 | Roberto Valducci | Coating membrane and compositions prepared therefrom |
| US5008118A (en) * | 1987-06-23 | 1991-04-16 | Nippon Oil And Fats | Method for producing organic agent coated with powders of coating agent |
| DE3721721C1 (de) * | 1987-07-01 | 1988-06-09 | Hoechst Ag | Verfahren zur Umhuellung von Granulaten |
| US4935246A (en) * | 1987-07-01 | 1990-06-19 | Hoechst Aktiengesellschaft | Process for the coating of granules |
| US5662935A (en) * | 1992-12-23 | 1997-09-02 | Saitec S.R.L. | Process for preparing controlled release pharmaceutical forms and the forms thus obtained |
| US5707636A (en) * | 1994-08-03 | 1998-01-13 | Saitec S.R.L. | Apparatus and method for preparing solid forms with controlled release of the active ingredient |
| EP1872779A1 (de) * | 2006-06-28 | 2008-01-02 | Oramon Arzneimittel GmbH | Stabile multipartikuläre pharmazeutische Zusammensetzung von tri- und tetracyclischen Antidepressiva |
Also Published As
| Publication number | Publication date |
|---|---|
| FR4731M (enrdf_load_stackoverflow) | 1967-01-09 |
| ES297425A1 (es) | 1964-06-01 |
| BE644643A (enrdf_load_stackoverflow) | 1964-09-03 |
| BR6457270D0 (pt) | 1973-09-20 |
| NL6402159A (enrdf_load_stackoverflow) | 1964-09-07 |
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