GB1040892A - A method of producing 3,5-diiodothyronines - Google Patents
A method of producing 3,5-diiodothyroninesInfo
- Publication number
- GB1040892A GB1040892A GB246/64A GB24664A GB1040892A GB 1040892 A GB1040892 A GB 1040892A GB 246/64 A GB246/64 A GB 246/64A GB 24664 A GB24664 A GB 24664A GB 1040892 A GB1040892 A GB 1040892A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diiodothyronines
- producing
- complex
- phenoxyphenylalanine
- diiodothyronine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A new method of producing 3,5-diiodothyronines comprises the steps of converting racemic or optically active 3,5-diiodotyrosine to a metal complex of cations which form complexes with amino-acids, reacting said complex in the presence of bases with a 4,41-dialkoxy-diphenyliodonium salt to form a 3,5-diiodo-4-p-alkoxy-phenoxyphenylalanine and dealkylating the latter to the corresponding 3,5-diiodothyronine.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT17363A AT243246B (en) | 1963-01-09 | 1963-01-09 | Process for the preparation of racemic or optically active 3, 5-diiodothyronine |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1040892A true GB1040892A (en) | 1966-09-01 |
Family
ID=3483501
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB246/64A Expired GB1040892A (en) | 1963-01-09 | 1964-01-02 | A method of producing 3,5-diiodothyronines |
Country Status (7)
Country | Link |
---|---|
US (1) | US3374269A (en) |
AT (1) | AT243246B (en) |
CH (1) | CH439328A (en) |
DE (1) | DE1221646B (en) |
DK (1) | DK114904B (en) |
GB (1) | GB1040892A (en) |
NL (2) | NL6400050A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3477954A (en) * | 1966-06-29 | 1969-11-11 | Armour Pharma | Phosphonium iodide complexes of thyroxine,methods of preparing same,and methods of preparing 3,5,3'-l-triiodothyronine therefrom |
EP3024326B1 (en) | 2013-07-24 | 2018-12-12 | Azico Biophore India Private Limited | Novel process for the preparation of levothyroxine sodium |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2895927A (en) * | 1957-07-05 | 1959-07-21 | Hoffmann La Roche | Synthesis of thyronine compounds |
-
0
- NL NL127987D patent/NL127987C/xx active
-
1963
- 1963-01-09 AT AT17363A patent/AT243246B/en active
- 1963-12-20 DE DES88831A patent/DE1221646B/en active Pending
- 1963-12-23 CH CH1584363A patent/CH439328A/en unknown
- 1963-12-30 DK DK609563AA patent/DK114904B/en unknown
-
1964
- 1964-01-02 US US335387A patent/US3374269A/en not_active Expired - Lifetime
- 1964-01-02 GB GB246/64A patent/GB1040892A/en not_active Expired
- 1964-01-07 NL NL6400050A patent/NL6400050A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CH439328A (en) | 1967-07-15 |
NL6400050A (en) | 1964-07-10 |
DK114904B (en) | 1969-08-18 |
NL127987C (en) | |
AT243246B (en) | 1965-10-25 |
DE1221646B (en) | 1966-07-28 |
US3374269A (en) | 1968-03-19 |
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