GB1040337A - Improvements in or relating to the manufacture of suppositories - Google Patents
Improvements in or relating to the manufacture of suppositoriesInfo
- Publication number
- GB1040337A GB1040337A GB2285262A GB2285262A GB1040337A GB 1040337 A GB1040337 A GB 1040337A GB 2285262 A GB2285262 A GB 2285262A GB 2285262 A GB2285262 A GB 2285262A GB 1040337 A GB1040337 A GB 1040337A
- Authority
- GB
- United Kingdom
- Prior art keywords
- core
- mixture
- active ingredient
- inert base
- polyvinyl pyrrolidone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
Abstract
A suppository comprises a core containing an active ingredient mixed with an inert base and coated with a substance which contains no active ingredient but serves as a lubricant when the suppository is inserted in the body. The active ingredient or ingredients e.g. oxycodone pectinate, morphine pectinate, theophylline or a mixture of hydrocortisone acetate, benzocaine and bismuth subgallate, are mixed and moist granulated with an inert base e.g. maize starch, lactose, polyvinyl pyrrolidone, kaolin levis or mixtures thereof. The mixture is shaped and compressed to form a core. The coating comprising hydrogenated fat, a mixture of polyethylene glycols in alcohol, cocoa butter or a polyvinyl pyrrolidone is applied to the core in a coating pan. The disintegration time of the core is controlled by adjusting the composition or the compactness of the inert base.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE633551D BE633551A (en) | 1962-06-14 | ||
NL294106D NL294106A (en) | 1962-06-14 | ||
GB2285262A GB1040337A (en) | 1962-06-14 | 1962-06-14 | Improvements in or relating to the manufacture of suppositories |
FR938241A FR5186M (en) | 1962-06-14 | 1963-06-14 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2285262A GB1040337A (en) | 1962-06-14 | 1962-06-14 | Improvements in or relating to the manufacture of suppositories |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1040337A true GB1040337A (en) | 1966-08-24 |
Family
ID=10186080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2285262A Expired GB1040337A (en) | 1962-06-14 | 1962-06-14 | Improvements in or relating to the manufacture of suppositories |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE633551A (en) |
FR (1) | FR5186M (en) |
GB (1) | GB1040337A (en) |
NL (1) | NL294106A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2355406A (en) * | 1999-10-23 | 2001-04-25 | Alkaloid Ad | A sub-lingual dosage form comprising a morphine salt |
-
0
- NL NL294106D patent/NL294106A/xx unknown
- BE BE633551D patent/BE633551A/xx unknown
-
1962
- 1962-06-14 GB GB2285262A patent/GB1040337A/en not_active Expired
-
1963
- 1963-06-14 FR FR938241A patent/FR5186M/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2355406A (en) * | 1999-10-23 | 2001-04-25 | Alkaloid Ad | A sub-lingual dosage form comprising a morphine salt |
Also Published As
Publication number | Publication date |
---|---|
FR5186M (en) | 1967-06-26 |
BE633551A (en) | |
NL294106A (en) |
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