GB1034872A - Benzodiazepine derivatives - Google Patents
Benzodiazepine derivativesInfo
- Publication number
- GB1034872A GB1034872A GB1425563A GB1425563A GB1034872A GB 1034872 A GB1034872 A GB 1034872A GB 1425563 A GB1425563 A GB 1425563A GB 1425563 A GB1425563 A GB 1425563A GB 1034872 A GB1034872 A GB 1034872A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- carbon atoms
- amino radical
- hydrogen
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940053197 benzodiazepine derivative antiepileptics Drugs 0.000 title 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical class [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 230000001773 anti-convulsant effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000000467 secondary amino group Chemical class [H]N([*:1])[*:2] 0.000 abstract 1
- 229940125723 sedative agent Drugs 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18798362A | 1962-04-16 | 1962-04-16 | |
| US247460A US3197467A (en) | 1962-12-20 | 1962-12-20 | Process for preparing 1, 3-dihydro-3-hydroxy-2h-1, 4-benzodiazepin-2-ones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1034872A true GB1034872A (en) | 1966-07-06 |
Family
ID=26883617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1425563A Expired GB1034872A (en) | 1962-04-16 | 1963-04-10 | Benzodiazepine derivatives |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE1545555B2 (enrdf_load_stackoverflow) |
| GB (1) | GB1034872A (enrdf_load_stackoverflow) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2154508A1 (enrdf_load_stackoverflow) * | 1971-09-15 | 1973-05-11 | Crc Ricerca Chim | |
| EP0167919A3 (en) * | 1984-06-26 | 1986-11-05 | Merck & Co. Inc. | Benzodiazepine derivatives and pharmaceutical compositions containing them |
| US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| US4957915A (en) * | 1989-02-27 | 1990-09-18 | Biomeasure, Inc. | Benzodiazepine analogs |
-
1963
- 1963-04-10 GB GB1425563A patent/GB1034872A/en not_active Expired
- 1963-04-16 DE DE19631545555 patent/DE1545555B2/de active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2154508A1 (enrdf_load_stackoverflow) * | 1971-09-15 | 1973-05-11 | Crc Ricerca Chim | |
| US3852274A (en) * | 1971-09-15 | 1974-12-03 | Crc Ricerca Chim | Derivatives of 1,4-benzodiazepin-2-one and methods for preparation thereof |
| EP0167919A3 (en) * | 1984-06-26 | 1986-11-05 | Merck & Co. Inc. | Benzodiazepine derivatives and pharmaceutical compositions containing them |
| US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| EP0284256B1 (en) * | 1987-03-16 | 1994-06-01 | Merck & Co. Inc. | Benzodiazepine analogs |
| US4957915A (en) * | 1989-02-27 | 1990-09-18 | Biomeasure, Inc. | Benzodiazepine analogs |
Also Published As
| Publication number | Publication date |
|---|---|
| DE1545555A1 (de) | 1970-04-09 |
| DE1545555B2 (de) | 1975-08-07 |
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