GB1033905A - Process for the production of a new pentapeptide - Google Patents
Process for the production of a new pentapeptideInfo
- Publication number
- GB1033905A GB1033905A GB2407/66A GB240766A GB1033905A GB 1033905 A GB1033905 A GB 1033905A GB 2407/66 A GB2407/66 A GB 2407/66A GB 240766 A GB240766 A GB 240766A GB 1033905 A GB1033905 A GB 1033905A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cbo
- ile
- glynh2
- reacting
- hpro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The pentapeptide, HAsp(NH2)-S-Bz-Cys-Pro-Ile-GlyNH2 (Bz = Benzyl) is prepared by reacting CBO-Asp(NH2)-S-Bz-Cys-O-Alkyl (or O-Aralkyl) (CBO = carbobenzoxy) with hydrazine, converting the hydrazide with nitrous acid into the azide, reacting this with HPro-Ile-GlyNH2 and removing the CBO-group from the product or by reacting CBO-Asp(NH2)-S-Bz-Cys-OH with HPro-Ile-GlyNH2 in the presence of a carbodiimide. HPro Ile-GlyNH2 is prepared by reacting HIleGlyOEt with CBO-ProOH to give CBO-Pro-Ile-GlyOH, forming the amide and removing the CBO-group.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH386362A CH440310A (en) | 1962-03-30 | 1962-03-30 | Process for the preparation of a new nonapeptide amide |
CH1201062 | 1962-10-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1033905A true GB1033905A (en) | 1966-06-22 |
Family
ID=25694033
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2408/66A Expired GB1033906A (en) | 1962-03-30 | 1963-03-22 | Process for the production of a new tetrapeptide |
GB11375/63A Expired GB1033904A (en) | 1962-03-30 | 1963-03-22 | Process for the production of a new nonapeptidamide |
GB2407/66A Expired GB1033905A (en) | 1962-03-30 | 1963-03-22 | Process for the production of a new pentapeptide |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2408/66A Expired GB1033906A (en) | 1962-03-30 | 1963-03-22 | Process for the production of a new tetrapeptide |
GB11375/63A Expired GB1033904A (en) | 1962-03-30 | 1963-03-22 | Process for the production of a new nonapeptidamide |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE630332A (en) |
ES (1) | ES286566A1 (en) |
FR (1) | FR3565M (en) |
GB (3) | GB1033906A (en) |
SE (1) | SE322229B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4018912A (en) * | 1975-07-28 | 1977-04-19 | Ayerst Mckenna And Harrison Ltd. | Tripeptide derivatives with central nervous system activity and preparation thereof |
-
1963
- 1963-03-22 GB GB2408/66A patent/GB1033906A/en not_active Expired
- 1963-03-22 GB GB11375/63A patent/GB1033904A/en not_active Expired
- 1963-03-22 GB GB2407/66A patent/GB1033905A/en not_active Expired
- 1963-03-29 SE SE3490/63A patent/SE322229B/xx unknown
- 1963-03-29 ES ES286566A patent/ES286566A1/en not_active Expired
- 1963-03-29 BE BE630332A patent/BE630332A/fr unknown
- 1963-06-28 FR FR939708A patent/FR3565M/en active Active
Also Published As
Publication number | Publication date |
---|---|
GB1033904A (en) | 1966-06-22 |
ES286566A1 (en) | 1963-11-16 |
SE322229B (en) | 1970-04-06 |
BE630332A (en) | 1963-10-21 |
GB1033906A (en) | 1966-06-22 |
FR3565M (en) | 1965-09-27 |
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