GB1033737A - Topical medicaments comprising protamine and its derivatives - Google Patents
Topical medicaments comprising protamine and its derivativesInfo
- Publication number
- GB1033737A GB1033737A GB2362363A GB2362363A GB1033737A GB 1033737 A GB1033737 A GB 1033737A GB 2362363 A GB2362363 A GB 2362363A GB 2362363 A GB2362363 A GB 2362363A GB 1033737 A GB1033737 A GB 1033737A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compositions
- protamine
- contain
- hydrocortisone
- physiologically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
Abstract
Aerosol compositions for the treatment of skin cancer comprise protamine, or a physiologically-compatible salt thereof, and a propellant. Specified propellants are dichlorodifluoromethane, difluoroethane, and trichlorofluoromethane. The compositions may contain one or more anti-inflammatory or analgesic substances, e.g. hydrocortisone, preservatives, oils, or emulsifying agents.ALSO:Pharmaceutical compositions for the treatment of skin cancer comprise protamine, or a physiologically-compatible salt thereof, and a topical vehicle. The compositions may contain one or more anti-inflammatory or analgesic substances e.g. hydrocortisone. The compositions may be in the form of ointments, lotions, creams, sticks, emulsions, powders, solutions, spray solutions, nasal spray solutions, aerosols, lozenges, paints for the nose, mouth and pharynx and rectal and vaginal suppositories. In aqueous preparations, the solubility in water of the protamine can be improved by the presence of formaldehyde-bisulphite or formaldehyde-sulphoxylate complex. The pH of the preparations should preferably be neutral or be within the range 4-7. The compositions may contain one or more preservatives and conventional excipients where necessary.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2362363A GB1033737A (en) | 1963-06-13 | 1963-06-13 | Topical medicaments comprising protamine and its derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2362363A GB1033737A (en) | 1963-06-13 | 1963-06-13 | Topical medicaments comprising protamine and its derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1033737A true GB1033737A (en) | 1966-06-22 |
Family
ID=10198647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2362363A Expired GB1033737A (en) | 1963-06-13 | 1963-06-13 | Topical medicaments comprising protamine and its derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1033737A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3997659A (en) * | 1971-03-30 | 1976-12-14 | The Procter & Gamble Company | Hair bleaching compositions containing an arginine compound |
WO1999038500A2 (en) * | 1998-01-30 | 1999-08-05 | The Brigham And Women's Hospital, Inc. | The human calcium-sensing receptor in the detection and treatment of cancer |
US6624141B1 (en) * | 1999-03-17 | 2003-09-23 | The Regents Of The University Of Michigan | Protamine fragment compositions and methods of use |
EP2113257A1 (en) * | 2008-04-30 | 2009-11-04 | Consorzio per il Centro di Biomedica Moleculare Scrl | Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer |
US20160058817A1 (en) * | 2014-08-26 | 2016-03-03 | Stephen K. Richardson | Treatment of precancerous lesions with Sanguinaria Canadensis Extract/Compounded Extract |
-
1963
- 1963-06-13 GB GB2362363A patent/GB1033737A/en not_active Expired
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3997659A (en) * | 1971-03-30 | 1976-12-14 | The Procter & Gamble Company | Hair bleaching compositions containing an arginine compound |
WO1999038500A2 (en) * | 1998-01-30 | 1999-08-05 | The Brigham And Women's Hospital, Inc. | The human calcium-sensing receptor in the detection and treatment of cancer |
WO1999038500A3 (en) * | 1998-01-30 | 2000-04-13 | Brigham & Womens Hospital | The human calcium-sensing receptor in the detection and treatment of cancer |
US6296833B1 (en) | 1998-01-30 | 2001-10-02 | The Brigham And Women's Hospital, Inc. | Human calcium-sensing receptor in the detection and treatment of cancer |
US6624141B1 (en) * | 1999-03-17 | 2003-09-23 | The Regents Of The University Of Michigan | Protamine fragment compositions and methods of use |
EP2113257A1 (en) * | 2008-04-30 | 2009-11-04 | Consorzio per il Centro di Biomedica Moleculare Scrl | Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer |
US20160058817A1 (en) * | 2014-08-26 | 2016-03-03 | Stephen K. Richardson | Treatment of precancerous lesions with Sanguinaria Canadensis Extract/Compounded Extract |
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