GB1033737A - Topical medicaments comprising protamine and its derivatives - Google Patents

Topical medicaments comprising protamine and its derivatives

Info

Publication number
GB1033737A
GB1033737A GB2362363A GB2362363A GB1033737A GB 1033737 A GB1033737 A GB 1033737A GB 2362363 A GB2362363 A GB 2362363A GB 2362363 A GB2362363 A GB 2362363A GB 1033737 A GB1033737 A GB 1033737A
Authority
GB
United Kingdom
Prior art keywords
compositions
protamine
contain
hydrocortisone
physiologically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2362363A
Inventor
Robert Allen Quain O'meara
Eric Michael Glaser
Richard Marsden
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Pharma Ltd
Original Assignee
Evans Medical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evans Medical Ltd filed Critical Evans Medical Ltd
Priority to GB2362363A priority Critical patent/GB1033737A/en
Publication of GB1033737A publication Critical patent/GB1033737A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Abstract

Aerosol compositions for the treatment of skin cancer comprise protamine, or a physiologically-compatible salt thereof, and a propellant. Specified propellants are dichlorodifluoromethane, difluoroethane, and trichlorofluoromethane. The compositions may contain one or more anti-inflammatory or analgesic substances, e.g. hydrocortisone, preservatives, oils, or emulsifying agents.ALSO:Pharmaceutical compositions for the treatment of skin cancer comprise protamine, or a physiologically-compatible salt thereof, and a topical vehicle. The compositions may contain one or more anti-inflammatory or analgesic substances e.g. hydrocortisone. The compositions may be in the form of ointments, lotions, creams, sticks, emulsions, powders, solutions, spray solutions, nasal spray solutions, aerosols, lozenges, paints for the nose, mouth and pharynx and rectal and vaginal suppositories. In aqueous preparations, the solubility in water of the protamine can be improved by the presence of formaldehyde-bisulphite or formaldehyde-sulphoxylate complex. The pH of the preparations should preferably be neutral or be within the range 4-7. The compositions may contain one or more preservatives and conventional excipients where necessary.
GB2362363A 1963-06-13 1963-06-13 Topical medicaments comprising protamine and its derivatives Expired GB1033737A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2362363A GB1033737A (en) 1963-06-13 1963-06-13 Topical medicaments comprising protamine and its derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2362363A GB1033737A (en) 1963-06-13 1963-06-13 Topical medicaments comprising protamine and its derivatives

Publications (1)

Publication Number Publication Date
GB1033737A true GB1033737A (en) 1966-06-22

Family

ID=10198647

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2362363A Expired GB1033737A (en) 1963-06-13 1963-06-13 Topical medicaments comprising protamine and its derivatives

Country Status (1)

Country Link
GB (1) GB1033737A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997659A (en) * 1971-03-30 1976-12-14 The Procter & Gamble Company Hair bleaching compositions containing an arginine compound
WO1999038500A2 (en) * 1998-01-30 1999-08-05 The Brigham And Women's Hospital, Inc. The human calcium-sensing receptor in the detection and treatment of cancer
US6624141B1 (en) * 1999-03-17 2003-09-23 The Regents Of The University Of Michigan Protamine fragment compositions and methods of use
EP2113257A1 (en) * 2008-04-30 2009-11-04 Consorzio per il Centro di Biomedica Moleculare Scrl Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer
US20160058817A1 (en) * 2014-08-26 2016-03-03 Stephen K. Richardson Treatment of precancerous lesions with Sanguinaria Canadensis Extract/Compounded Extract

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997659A (en) * 1971-03-30 1976-12-14 The Procter & Gamble Company Hair bleaching compositions containing an arginine compound
WO1999038500A2 (en) * 1998-01-30 1999-08-05 The Brigham And Women's Hospital, Inc. The human calcium-sensing receptor in the detection and treatment of cancer
WO1999038500A3 (en) * 1998-01-30 2000-04-13 Brigham & Womens Hospital The human calcium-sensing receptor in the detection and treatment of cancer
US6296833B1 (en) 1998-01-30 2001-10-02 The Brigham And Women's Hospital, Inc. Human calcium-sensing receptor in the detection and treatment of cancer
US6624141B1 (en) * 1999-03-17 2003-09-23 The Regents Of The University Of Michigan Protamine fragment compositions and methods of use
EP2113257A1 (en) * 2008-04-30 2009-11-04 Consorzio per il Centro di Biomedica Moleculare Scrl Polyelectrolyte with positive net charge for use as medicament and diagnostic for cancer
US20160058817A1 (en) * 2014-08-26 2016-03-03 Stephen K. Richardson Treatment of precancerous lesions with Sanguinaria Canadensis Extract/Compounded Extract

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