GB0615211D0 - Asymmetric flouro-substituted polymethine dyes - Google Patents

Asymmetric flouro-substituted polymethine dyes

Info

Publication number
GB0615211D0
GB0615211D0 GB0615211A GB0615211A GB0615211D0 GB 0615211 D0 GB0615211 D0 GB 0615211D0 GB 0615211 A GB0615211 A GB 0615211A GB 0615211 A GB0615211 A GB 0615211A GB 0615211 D0 GB0615211 D0 GB 0615211D0
Authority
GB
United Kingdom
Prior art keywords
conjugates
asymmetric
dyes
flouro
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GB0615211A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare UK Ltd
Original Assignee
GE Healthcare UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare UK Ltd filed Critical GE Healthcare UK Ltd
Priority to GB0615211A priority Critical patent/GB0615211D0/en
Publication of GB0615211D0 publication Critical patent/GB0615211D0/en
Priority to EP07789086A priority patent/EP2046895A2/en
Priority to JP2009522326A priority patent/JP5341757B2/ja
Priority to CN 200780036717 priority patent/CN101522815A/zh
Priority to PCT/GB2007/002907 priority patent/WO2008015415A2/en
Priority to US12/375,239 priority patent/US20090252687A1/en
Ceased legal-status Critical Current

Links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
GB0615211A 2006-07-31 2006-07-31 Asymmetric flouro-substituted polymethine dyes Ceased GB0615211D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB0615211A GB0615211D0 (en) 2006-07-31 2006-07-31 Asymmetric flouro-substituted polymethine dyes
EP07789086A EP2046895A2 (en) 2006-07-31 2007-07-31 Asymmetric fluoro-substituted polymethine dyes
JP2009522326A JP5341757B2 (ja) 2006-07-31 2007-07-31 非対称フルオロ置換ポリメチン色素
CN 200780036717 CN101522815A (zh) 2006-07-31 2007-07-31 不对称的氟取代的多次甲基染料
PCT/GB2007/002907 WO2008015415A2 (en) 2006-07-31 2007-07-31 Asymmetric fluoro-substituted polymethine dyes
US12/375,239 US20090252687A1 (en) 2006-07-31 2007-07-31 Asymmetric fluoro-substituted polymethine dyes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0615211A GB0615211D0 (en) 2006-07-31 2006-07-31 Asymmetric flouro-substituted polymethine dyes

Publications (1)

Publication Number Publication Date
GB0615211D0 true GB0615211D0 (en) 2006-09-06

Family

ID=37006503

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0615211A Ceased GB0615211D0 (en) 2006-07-31 2006-07-31 Asymmetric flouro-substituted polymethine dyes

Country Status (6)

Country Link
US (1) US20090252687A1 (enExample)
EP (1) EP2046895A2 (enExample)
JP (1) JP5341757B2 (enExample)
CN (1) CN101522815A (enExample)
GB (1) GB0615211D0 (enExample)
WO (1) WO2008015415A2 (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0718957D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Optical imaging agents
GB0718967D0 (en) * 2007-09-28 2007-11-07 Ge Healthcare Ltd Peptide imaging agents
EP3118201A1 (en) * 2007-10-02 2017-01-18 Thermo Fisher Scientific Inc. Monomethine dyes
SG2014009146A (en) 2009-02-06 2014-05-29 Beth Israel Hospital Charge-balanced imaging agents
US10493169B2 (en) 2009-02-06 2019-12-03 Beth Israel Deaconess Medical Center Use of charge-balanced imaging agents for determining renal function
EP2426123B1 (en) * 2009-04-28 2014-08-06 Wako Pure Chemical Industries, Ltd. Pyrazole-based cyanine dye containing quaternary ammonium cation
TWI516264B (zh) * 2010-05-06 2016-01-11 臺北醫學大學 芳香醯喹啉化合物
EP2588541A1 (en) * 2010-06-29 2013-05-08 GE Healthcare AS Dye compositions and dye syntheses
DE102010027016A1 (de) 2010-07-09 2012-01-12 Universitätsklinikum Jena Steroid-Styrylfarbstoff-Konjugate zur Simulation und direkten lichtoptischen Detektion des Verhaltens von Steroiden im lebenden biologischen Gewebe und in Gegenwart von steroidbindenden Proteinen
GB201013808D0 (en) 2010-08-18 2010-09-29 Ge Healthcare Ltd Peptide radiotracer compositions
WO2012061403A1 (en) * 2010-11-02 2012-05-10 Life Technologies Corporation Modified hydrocyanine dyes for the detection of reactive oxygen species
CN104395407B (zh) * 2012-03-30 2016-07-13 生命科技公司 用于检测活性氧的经修饰的结合核酸的花青染料
US9676787B2 (en) 2012-08-28 2017-06-13 Pierce Biotechnology, Inc. Benzopyrylium compounds
US10131682B2 (en) 2012-11-24 2018-11-20 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to a cell binding molecules
EP3797798B1 (en) 2013-03-14 2022-09-28 Profusa, Inc. Oxygen sensors
GB201314936D0 (en) 2013-08-21 2013-10-02 Ge Healthcare Ltd Radiolabelling method
GB201322456D0 (en) 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
CN104804463B (zh) * 2015-03-10 2016-08-24 西安交通大学第一附属医院 用于靶向肿瘤组织的近红外荧光染色剂及制备方法和应用
CN115505280A (zh) 2016-12-21 2022-12-23 普罗菲尤萨股份有限公司 可聚合的近红外染料
EP3375353A1 (en) * 2017-03-16 2018-09-19 Universität Zürich Photoacoustic imaging of inflamed tissue
WO2018187295A1 (en) 2017-04-03 2018-10-11 Massachusetts Institute Of Technology Near and shortwave infrared polymethine dyes
EP3634397A4 (en) 2017-06-05 2021-03-17 The Regents of The University of California HETEROCYCLYL-POLYMETHINIR-IR-CHROMOPHORE
CN111712468A (zh) * 2017-12-22 2020-09-25 北卡罗莱纳州立大学 聚合物荧光团、包含其的组合物及制备和使用其的方法
JP7561037B2 (ja) 2018-06-27 2024-10-03 プロフサ，インコーポレイテッド 近赤外線グルコースセンサー
CN117368301B (zh) * 2022-06-29 2026-04-14 中国科学院大连化学物理研究所 一种组织中巯基化合物的质谱成像检测方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658751A (en) * 1993-04-13 1997-08-19 Molecular Probes, Inc. Substituted unsymmetrical cyanine dyes with selected permeability
US6495692B1 (en) * 1996-12-10 2002-12-17 Abbott Laboratories Helium-neon excitable reticulocyte dyes derivable from halolepidines
EP1325084A2 (de) * 1998-12-05 2003-07-09 Otto Samuel Wolfbeis Pyridin- und chinolin-farbstoffe als marker für biomoleküle, polymere, arzneistoffe und partikel
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
ES2676151T3 (es) * 2000-01-19 2018-07-17 Abbvie Inc. Formulaciones farmacéuticas mejoradas
AU6581101A (en) * 2000-05-23 2001-12-03 Dyomics Gmbh Stable near-infrared (nir) marker dyes based on benzopyrylium-polymethines
CN1622830A (zh) * 2001-07-10 2005-06-01 安盛药业有限公司 肽基化合物
TWI244494B (en) * 2003-05-14 2005-12-01 Ritek Corp Optical recording medium dye
CA2599709A1 (en) * 2005-03-09 2006-09-21 Cepheid Polar dyes

Also Published As

Publication number Publication date
WO2008015415A2 (en) 2008-02-07
WO2008015415A3 (en) 2008-05-08
US20090252687A1 (en) 2009-10-08
JP5341757B2 (ja) 2013-11-13
JP2009545645A (ja) 2009-12-24
CN101522815A (zh) 2009-09-02
EP2046895A2 (en) 2009-04-15

Similar Documents

Publication Publication Date Title
WO2008015415A3 (en) Asymmetric fluoro-substituted polymethine dyes
Zhang et al. Bioorthogonally activatable cyanine dye with torsion-induced disaggregation for in vivo tumor imaging
Jose et al. Sensing and bioimaging of the gaseous signaling molecule hydrogen sulfide by near-infrared fluorescent probes
Zheng et al. Development of photostable fluorophores for molecular imaging
WO2010121163A3 (en) Fluorescent imaging with substituted cyanine dyes
Pliquett et al. A promising family of fluorescent water-soluble aza-BODIPY dyes for in vivo molecular imaging
Zhang et al. Rationally designed organelle-specific thermally activated delayed fluorescence small molecule organic probes for time-resolved biological applications
Niu et al. Water-soluble BODIPY derivatives
Napp et al. Targeted luminescent near-infrared polymer-nanoprobes for in vivo imaging of tumor hypoxia
Yang et al. Highly selective red-and green-emitting two-photon fluorescent probes for cysteine detection and their bio-imaging in living cells
US8168804B2 (en) Large stoke shift NIR dyes
Bohländer et al. Synthesis and evaluation of cyanine–styryl dyes with enhanced photostability for fluorescent DNA staining
SG165300A1 (en) Reactive heterocycle-substituted 7-hydroxycoumarins and their conjugates
Wu et al. Naphthalimide-modified near-infrared cyanine dye with a large stokes shift and its application in bioimaging
WO2007005222A8 (en) Cyanine dyes and methods of use in biological applications
WO2006020947A3 (en) Phosphonate fluorescent dyes and conjugates
EP2850078B1 (en) Benzopyrylium compounds
WO2012048063A3 (en) Cyanine compounds, conjugates and method of use
Mohammad et al. Structurally modified indocyanine green dyes. Modification of the polyene linker
Pauli et al. New fluorescent labels with tunable hydrophilicity for the rational design of bright optical probes for molecular imaging
MX2009012358A (es) Agentes de formacion de imagenes opticas.
EA201000333A1 (ru) Диагностические вещества на основе композиций наночастиц для тестирования посредством оптической визуализации
WO2020033681A3 (en) Silicon-substituted rhodamine dyes and dye conjugates
Deng et al. A nucleic acid-specific fluorescent probe for nucleolus imaging in living cells
Byun et al. Highly photostable fluorescent probes for multi-color and super-resolution imaging of cell organelles

Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)