GB0607063D0 - Compositions and methods for epigenetic modification of nucleic acid sequences in vivo - Google Patents

Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Info

Publication number
GB0607063D0
GB0607063D0 GBGB0607063.5A GB0607063A GB0607063D0 GB 0607063 D0 GB0607063 D0 GB 0607063D0 GB 0607063 A GB0607063 A GB 0607063A GB 0607063 D0 GB0607063 D0 GB 0607063D0
Authority
GB
United Kingdom
Prior art keywords
vivo
compositions
methods
nucleic acid
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0607063.5A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CellCentric Ltd
Original Assignee
CellCentric Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CellCentric Ltd filed Critical CellCentric Ltd
Priority to GBGB0607063.5A priority Critical patent/GB0607063D0/en
Publication of GB0607063D0 publication Critical patent/GB0607063D0/en
Priority to GBGB0623644.2A priority patent/GB0623644D0/en
Priority to EP07732348.3A priority patent/EP2010660B1/en
Priority to US12/226,094 priority patent/US8298529B2/en
Priority to JP2009503661A priority patent/JP2009532053A/ja
Priority to PCT/GB2007/001304 priority patent/WO2007128982A2/en
Priority to US13/646,008 priority patent/US8658393B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • C12N15/877—Techniques for producing new mammalian cloned embryos
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/09—Fusion polypeptide containing a localisation/targetting motif containing a nuclear localisation signal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
GBGB0607063.5A 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo Ceased GB0607063D0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
GBGB0607063.5A GB0607063D0 (en) 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
GBGB0623644.2A GB0623644D0 (en) 2006-04-07 2006-11-27 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
EP07732348.3A EP2010660B1 (en) 2006-04-07 2007-04-10 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
US12/226,094 US8298529B2 (en) 2006-04-07 2007-04-10 Compositions and method for epigenetic modification of nucleic acid sequences in vivo
JP2009503661A JP2009532053A (ja) 2006-04-07 2007-04-10 インヴィヴォでの核酸配列のエピジェネティック修飾用組成物および方法
PCT/GB2007/001304 WO2007128982A2 (en) 2006-04-07 2007-04-10 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
US13/646,008 US8658393B2 (en) 2006-04-07 2012-10-05 Molecules and methods for demethylation of methylated nucleic acid sequences

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0607063.5A GB0607063D0 (en) 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Publications (1)

Publication Number Publication Date
GB0607063D0 true GB0607063D0 (en) 2006-05-17

Family

ID=36539563

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB0607063.5A Ceased GB0607063D0 (en) 2006-04-07 2006-04-07 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo
GBGB0623644.2A Ceased GB0623644D0 (en) 2006-04-07 2006-11-27 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Family Applications After (1)

Application Number Title Priority Date Filing Date
GBGB0623644.2A Ceased GB0623644D0 (en) 2006-04-07 2006-11-27 Compositions and methods for epigenetic modification of nucleic acid sequences in vivo

Country Status (5)

Country Link
US (2) US8298529B2 (cg-RX-API-DMAC7.html)
EP (1) EP2010660B1 (cg-RX-API-DMAC7.html)
JP (1) JP2009532053A (cg-RX-API-DMAC7.html)
GB (2) GB0607063D0 (cg-RX-API-DMAC7.html)
WO (1) WO2007128982A2 (cg-RX-API-DMAC7.html)

Families Citing this family (21)

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CN102027118B (zh) * 2008-04-30 2014-07-30 桑比欧公司 含有dna甲基化状态改变的神经再生细胞
EP2128259A1 (en) * 2008-05-27 2009-12-02 Koninklijke Philips Electronics N.V. Therapy delivery and monitoring using a gene of interest-reporter fusion protein and optical imaging
EP2414507B1 (en) * 2009-04-03 2014-07-02 Medical Research Council Mutants of activation-induced cytidine deaminase (aid) and methods of use
EP2258858A1 (en) * 2009-06-05 2010-12-08 Universitätsklinikum Freiburg Transgenic LSD1 animal model for cancer
US20110104787A1 (en) * 2009-11-05 2011-05-05 President And Fellows Of Harvard College Fusion Peptides That Bind to and Modify Target Nucleic Acid Sequences
WO2011075627A1 (en) * 2009-12-18 2011-06-23 The Board Of Trustees Of The Leland Stanford Junior University Use of cytidine deaminase-related agents to promote demethylation and cell reprogramming
US20140274812A1 (en) 2011-07-15 2014-09-18 The General Hospital Corporation Methods of Transcription Activator Like Effector Assembly
US9890364B2 (en) 2012-05-29 2018-02-13 The General Hospital Corporation TAL-Tet1 fusion proteins and methods of use thereof
EP3789405A1 (en) 2012-10-12 2021-03-10 The General Hospital Corporation Transcription activator-like effector (tale) - lysine-specific demethylase 1 (lsd1) fusion proteins
CA2900338C (en) 2013-02-07 2024-11-05 The General Hospital Corporation TRANSCRIPTIONAL ACTIVATORS TALE
US9721248B2 (en) 2014-03-04 2017-08-01 Bank Of America Corporation ATM token cash withdrawal
GB201418965D0 (cg-RX-API-DMAC7.html) 2014-10-24 2014-12-10 Ospedale San Raffaele And Fond Telethon
US10460367B2 (en) 2016-04-29 2019-10-29 Bank Of America Corporation System for user authentication based on linking a randomly generated number to the user and a physical item
US10268635B2 (en) 2016-06-17 2019-04-23 Bank Of America Corporation System for data rotation through tokenization
WO2018122088A1 (en) * 2016-12-28 2018-07-05 Transgene Sa Oncolytic viruses and therapeutic molecules
CN117534769A (zh) 2018-04-19 2024-02-09 加利福尼亚大学董事会 用于基因编辑的组合物和方法
EP3841204A4 (en) * 2018-08-23 2022-05-18 Sangamo Therapeutics, Inc. CHANGED TARGET SPECIFIC BASE EDITORS
JP7059965B2 (ja) * 2019-02-21 2022-04-26 株式会社豊田中央研究所 エピゲノム状態を制御する融合タンパク質及びその利用
US11680109B2 (en) 2019-05-29 2023-06-20 Duke University Compositions and methods for detection and measurement of RNA modifications through targeted RNA editing
CN113383749B (zh) * 2020-03-12 2025-11-18 中国医学科学院基础医学研究所 一种使用单个肿瘤细胞构建小鼠肿瘤模型的方法
WO2022244544A1 (ja) * 2021-05-20 2022-11-24 国立大学法人群馬大学 エピゲノムが改変された動植物の親系統の製造に用いるための組成物およびその用途

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FR2646438B1 (fr) 1989-03-20 2007-11-02 Pasteur Institut Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
DE69720283T2 (de) 1996-12-30 2004-01-29 Univ Johns Hopkins Med Bestimmung der krebsanfälligkeit eines organs oder gewebes durch bestimmung seiner zellprägung
US6534261B1 (en) * 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
CA2365601A1 (en) * 1999-03-29 2000-10-05 Kansai Technology Licensing Organization Co., Ltd. Novel cytidine deaminase
AUPQ655100A0 (en) * 2000-03-29 2000-04-20 Am Asset Management Pty Ltd Device and method for cleaning golf balls
ATE353361T1 (de) 2000-04-28 2007-02-15 Sangamo Biosciences Inc Gezielten modifikation der chromatinstruktur
CA2416664A1 (en) 2000-07-21 2002-01-31 Syngenta Participations Ag Zinc finger domain recognition code and uses thereof
WO2002046412A2 (en) * 2000-12-07 2002-06-13 Sangamo Biosciences, Inc. Regulation of angiogenesis with zinc finger proteins
US8207142B2 (en) 2001-07-31 2012-06-26 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Inhibitor of DNA methylation
ES2421596T3 (es) * 2002-05-10 2013-09-04 Medical Res Council Desaminasa inducida por activación (AID)
GB0312676D0 (en) * 2003-06-02 2003-07-09 Babraham Inst Binding assay
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Also Published As

Publication number Publication date
WO2007128982A3 (en) 2008-02-21
US8298529B2 (en) 2012-10-30
US20130034881A1 (en) 2013-02-07
EP2010660A2 (en) 2009-01-07
US20110138491A1 (en) 2011-06-09
GB0623644D0 (en) 2007-01-03
EP2010660B1 (en) 2013-06-05
US8658393B2 (en) 2014-02-25
WO2007128982A2 (en) 2007-11-15
JP2009532053A (ja) 2009-09-10

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)