GB0422004D0 - Method of deprotection - Google Patents

Method of deprotection

Info

Publication number
GB0422004D0
GB0422004D0 GBGB0422004.2A GB0422004A GB0422004D0 GB 0422004 D0 GB0422004 D0 GB 0422004D0 GB 0422004 A GB0422004 A GB 0422004A GB 0422004 D0 GB0422004 D0 GB 0422004D0
Authority
GB
United Kingdom
Prior art keywords
deprotection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0422004.2A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
Amersham PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham PLC filed Critical Amersham PLC
Priority to GBGB0422004.2A priority Critical patent/GB0422004D0/en
Publication of GB0422004D0 publication Critical patent/GB0422004D0/en
Priority to EP05784549A priority patent/EP1797029A1/en
Priority to JP2007534071A priority patent/JP5000521B2/ja
Priority to CN2005800338074A priority patent/CN101035755B/zh
Priority to US11/576,625 priority patent/US7714115B2/en
Priority to PCT/GB2005/003692 priority patent/WO2006037950A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
GBGB0422004.2A 2004-10-05 2004-10-05 Method of deprotection Ceased GB0422004D0 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GBGB0422004.2A GB0422004D0 (en) 2004-10-05 2004-10-05 Method of deprotection
EP05784549A EP1797029A1 (en) 2004-10-05 2005-09-23 Method of deprotection
JP2007534071A JP5000521B2 (ja) 2004-10-05 2005-09-23 脱保護の方法
CN2005800338074A CN101035755B (zh) 2004-10-05 2005-09-23 脱保护的方法
US11/576,625 US7714115B2 (en) 2004-10-05 2005-09-23 Method of deprotection
PCT/GB2005/003692 WO2006037950A1 (en) 2004-10-05 2005-09-23 Method of deprotection

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0422004.2A GB0422004D0 (en) 2004-10-05 2004-10-05 Method of deprotection

Publications (1)

Publication Number Publication Date
GB0422004D0 true GB0422004D0 (en) 2004-11-03

Family

ID=33428035

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0422004.2A Ceased GB0422004D0 (en) 2004-10-05 2004-10-05 Method of deprotection

Country Status (6)

Country Link
US (1) US7714115B2 (enExample)
EP (1) EP1797029A1 (enExample)
JP (1) JP5000521B2 (enExample)
CN (1) CN101035755B (enExample)
GB (1) GB0422004D0 (enExample)
WO (1) WO2006037950A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070260267A1 (en) * 2002-10-07 2007-11-08 Nicoson Zachary R Localizing obturator
KR101497406B1 (ko) * 2006-12-21 2015-03-02 니혼 메디피직스 가부시키가이샤 방사성 화상 진단제
JP5518337B2 (ja) 2006-12-27 2014-06-11 日本メジフィジックス株式会社 放射性ハロゲン標識有機化合物の前駆体化合物の製造方法
CN101636183B (zh) * 2007-02-13 2014-03-19 日本医事物理股份有限公司 放射性诊断显像剂的制备方法
EP2005970A1 (de) 2007-06-22 2008-12-24 Berlin Science Partners GmbH i.V. Bildgebende Diagnostik durch Kombination von Kontrastmitteln
US8043316B2 (en) 2008-05-02 2011-10-25 Suros Surgical Systems, Inc. Adjustable spacer
GB0905515D0 (en) * 2009-03-31 2009-05-13 Ge Healthcare Ltd Radiolabelling methods
EP2501663A2 (en) * 2009-11-17 2012-09-26 Piramal Imaging SA Method for production of f-18 labeled glutamic acid derivatives
EP2582713A1 (en) * 2010-06-17 2013-04-24 MSD Oss B.V. (11 beta,17 alpha)-11-(4-(2-11c-acetyl)phenyl)-17,23-epoxy-19,24-dinorchola-4,9,20-trien-3-one
KR20130132892A (ko) * 2010-12-29 2013-12-05 지이 헬쓰케어 리미티드 용리제 용액
US9101895B2 (en) 2011-04-15 2015-08-11 General Electric Company System for mixing and dispersing microbubble pharmaceuticals
KR101221483B1 (ko) * 2011-05-13 2013-01-16 서강대학교산학협력단 Ｆ-18 표지 방사성의약품 합성 장치 및 방법
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
RU2623163C2 (ru) * 2011-12-21 2017-06-22 ДжиИ ХЕЛТКЕР ЛИМИТЕД Композиция 18f- флуцикловина в цитратных буферах
EP3151751A4 (en) * 2014-06-06 2018-02-21 The Regents of the University of California Self-shielded, benchtop chemistry system
LT3481804T (lt) 2016-06-10 2025-02-25 The Johns Hopkins University Radioaktyviai pažymėto prostatos specifinio membranos antigeno (psma) inhibitoriaus [18f]dcfpyl pagerinta sintezė
ES2916840T3 (es) * 2016-12-07 2022-07-06 Univ Degli Studi Di Bari Aldo Moro Formulaciones estables de F-DOPA y usos de las mismas
JP7159157B2 (ja) * 2017-06-23 2022-10-24 日本メジフィジックス株式会社 放射性フッ素標識化合物の製造方法および放射性医薬の製造方法
WO2022196734A1 (ja) * 2021-03-17 2022-09-22 Tdk株式会社 含フッ素化合物および造影剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135683A (en) * 1991-03-28 1992-08-04 Arco Chemical Technology, L.P. Process for producing a deprotected alkoxylated polyol
US5393908A (en) 1992-06-25 1995-02-28 Satyamurthy; Nagichettiar Synthesis of N-formyl-3,4-di-t-butoxycarbonyloxy-6-(trimethylstannyl)-L-phenylalanine ethyl ester and its regioselective radiofluorodestannylation to 6-[18 F]fluoro-L-dopa
DE4330889C2 (de) * 1993-09-11 2002-10-31 Emtec Magnetics Gmbh Verfahren zur Wiedergewinnung von Rohmaterialien aus magnetischen Aufzeichnungsträgern
US5922810A (en) * 1995-07-31 1999-07-13 Fmc Corporation Deprotection of protected functional polymers
BE1010280A3 (fr) * 1996-05-02 1998-05-05 Coincidence S A Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose.
DE10104250A1 (de) * 2001-01-31 2002-08-14 Deutsches Krebsforsch Markierungsfähige Verbindungen zur einfachen Synthese von 3'-[18F]Fluor-3'-deoxythymidin und Verfahren zu deren Herstellung
EP1356827A1 (en) 2002-04-24 2003-10-29 Mallinckrodt Inc. Method for obtaining a 2-18F-fluor-2-deoxy-D-glucose (18F-FDG)-solution
US7022872B2 (en) * 2003-12-19 2006-04-04 Molecular Technologies, Inc. Method for making fluorine labeled L-Dopa

Also Published As

Publication number Publication date
US20080076914A1 (en) 2008-03-27
US7714115B2 (en) 2010-05-11
WO2006037950A1 (en) 2006-04-13
EP1797029A1 (en) 2007-06-20
CN101035755B (zh) 2011-12-21
CN101035755A (zh) 2007-09-12
JP5000521B2 (ja) 2012-08-15
JP2008515793A (ja) 2008-05-15

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)