GB0321449D0 - Method for controlling protein aggregation and refolding - Google Patents

Method for controlling protein aggregation and refolding

Info

Publication number
GB0321449D0
GB0321449D0 GB0321449A GB0321449A GB0321449D0 GB 0321449 D0 GB0321449 D0 GB 0321449D0 GB 0321449 A GB0321449 A GB 0321449A GB 0321449 A GB0321449 A GB 0321449A GB 0321449 D0 GB0321449 D0 GB 0321449D0
Authority
GB
United Kingdom
Prior art keywords
refolding
protein aggregation
controlling protein
controlling
aggregation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB0321449A
Other versions
GB2405871A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novexin Ltd
Original Assignee
Novexin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novexin Ltd filed Critical Novexin Ltd
Priority to GB0321449A priority Critical patent/GB2405871A/en
Publication of GB0321449D0 publication Critical patent/GB0321449D0/en
Priority to GB0409088A priority patent/GB2405872A/en
Priority to PCT/GB2004/050009 priority patent/WO2005026196A2/en
Publication of GB2405871A publication Critical patent/GB2405871A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GB0321449A 2003-09-12 2003-09-12 Method for controlling protein folding Withdrawn GB2405871A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB0321449A GB2405871A (en) 2003-09-12 2003-09-12 Method for controlling protein folding
GB0409088A GB2405872A (en) 2003-09-12 2004-04-23 Method for protein folding and stabilisation
PCT/GB2004/050009 WO2005026196A2 (en) 2003-09-12 2004-09-13 Methods for folding proteins and reducing protein aggregation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0321449A GB2405871A (en) 2003-09-12 2003-09-12 Method for controlling protein folding

Publications (2)

Publication Number Publication Date
GB0321449D0 true GB0321449D0 (en) 2003-10-15
GB2405871A GB2405871A (en) 2005-03-16

Family

ID=29227014

Family Applications (2)

Application Number Title Priority Date Filing Date
GB0321449A Withdrawn GB2405871A (en) 2003-09-12 2003-09-12 Method for controlling protein folding
GB0409088A Withdrawn GB2405872A (en) 2003-09-12 2004-04-23 Method for protein folding and stabilisation

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0409088A Withdrawn GB2405872A (en) 2003-09-12 2004-04-23 Method for protein folding and stabilisation

Country Status (1)

Country Link
GB (2) GB2405871A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113004375A (en) * 2021-03-15 2021-06-22 华南农业大学 Small molecular protein for efficiently mediating recombinant polypeptide to form inclusion body

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1749018B1 (en) * 2004-04-23 2014-10-22 Expedeon Limited Methods and kits for stabilising, protecting and solubilising proteins
GB0505229D0 (en) 2005-03-15 2005-04-20 Novexin Ltd Methods for stabilising, protecting, solubilising and folding proteins
JP2008501314A (en) * 2004-04-23 2008-01-24 ノベシン リミテッド Method and kit for folding proteins in the presence of linear or branched sugar polymers
EP1967530A1 (en) * 2007-03-07 2008-09-10 Raffinerie Notre Dame - Orafti S.A. Natural rubber latex preservation
DE602008006701D1 (en) 2007-03-07 2011-06-16 Beneo Orafti S A PRESERVATION OF NATURAL RUBBER LATEX
CN101613681B (en) * 2008-06-24 2013-07-10 中国科学院上海生命科学研究院 Method for renaturing and purifying recombinant extremely heat-resistant alpha-amylase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4029287A1 (en) * 1990-09-14 1992-03-19 Sueddeutsche Kalkstickstoff METHOD FOR PRODUCING CHOLESTERIN-REDUCED EGG YELLOW
US5532005A (en) * 1992-05-29 1996-07-02 American Maize-Products Company Process for removal of residual cyclodextrin
US5563057A (en) * 1994-10-31 1996-10-08 Wisconsin Alumni Research Foundation Method for refolding misfolded enzymes with detergent and cyclodextrin
US5728804A (en) * 1995-06-02 1998-03-17 Research Corporation Technologies, Inc. Use of cyclodextrins for protein renaturation
IT1276684B1 (en) * 1995-06-08 1997-11-03 Bioextech Inc WATER-SOLUBLE FORMULATIONS OF STABILIZED COLLAGENASE AND PROCEDURE FOR THEIR PREPARATION

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113004375A (en) * 2021-03-15 2021-06-22 华南农业大学 Small molecular protein for efficiently mediating recombinant polypeptide to form inclusion body
CN113004375B (en) * 2021-03-15 2022-07-01 华南农业大学 Small molecular protein for efficiently mediating recombinant polypeptide to form inclusion body

Also Published As

Publication number Publication date
GB0409088D0 (en) 2004-05-26
GB2405872A (en) 2005-03-16
GB2405871A (en) 2005-03-16

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)