GB0100096D0 - Multiple vessel array - Google Patents

Multiple vessel array

Info

Publication number
GB0100096D0
GB0100096D0 GBGB0100096.7A GB0100096A GB0100096D0 GB 0100096 D0 GB0100096 D0 GB 0100096D0 GB 0100096 A GB0100096 A GB 0100096A GB 0100096 D0 GB0100096 D0 GB 0100096D0
Authority
GB
United Kingdom
Prior art keywords
vessel
reaction
closure member
flange
seal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB0100096.7A
Other versions
GB2370797A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avantium International BV
Original Assignee
Avantium International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantium International BV filed Critical Avantium International BV
Priority to GB0100096A priority Critical patent/GB2370797A/en
Publication of GB0100096D0 publication Critical patent/GB0100096D0/en
Priority to EP02710520A priority patent/EP1347829B1/en
Priority to DE60229211T priority patent/DE60229211D1/en
Priority to PCT/NL2002/000002 priority patent/WO2002053278A1/en
Priority to AT02710520T priority patent/ATE410226T1/en
Publication of GB2370797A publication Critical patent/GB2370797A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00281—Individual reactor vessels
    • B01J2219/00283—Reactor vessels with top opening
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B01J2219/00335—Septa
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00479—Means for mixing reactants or products in the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00479—Means for mixing reactants or products in the reaction vessels
    • B01J2219/00481—Means for mixing reactants or products in the reaction vessels by the use of moving stirrers within the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00479—Means for mixing reactants or products in the reaction vessels
    • B01J2219/00484—Means for mixing reactants or products in the reaction vessels by shaking, vibrating or oscillating of the reaction vessels
    • B01J2219/00486—Means for mixing reactants or products in the reaction vessels by shaking, vibrating or oscillating of the reaction vessels by sonication or ultrasonication
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00601—High-pressure processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Insulators (AREA)
  • Supplying Of Containers To The Packaging Station (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Abstract

An apparatus, such as laboratory reaction apparatus, comprises a multiple array of reaction vessels 40 (indicates a single such vessel), each of which has a flange 42 at or adjacent, and seal 43 associated with, an opening or a rim defining an opening of each vessel. The multiple vessel array is supported by a support member 30, relative to which is moveable, a closure member 20, which can be urged towards the rim of each reaction vessel 40, generally simultaneously to effect a fluid tight union between the reaction vessels 40 and the closure member 20. The apparatus may feature a plurality of such arrays and supporting features, shown in their closed configurations 2,3,4. Additional supporting features may include a temperature control block 50 with a hole 51 for each reaction vessel 40 and a gas manifold 26 and actuator 28 associated with the closure member 20. Several variations in the configuration of the flange 42 and seal 43 are disclosed across figures 2b-2h, which may additionally include a septum (23, fig.2g) enabling sampling / dosing of a reaction, or a safety bursting disc (24, fig.2h) mounted in a recess (25, fig.2h) of the closure member 20. The invention extends to physical and chemical processes carried out using the aforementioned apparatus comprising such steps as orbital shaking, stirring with rods, use of ultrasound, and heating or cooling.
GB0100096A 2001-01-03 2001-01-03 Sealing multiple arrays of reaction vessels, each with rim flange and seal, generally simultaneously with a single closure member Withdrawn GB2370797A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB0100096A GB2370797A (en) 2001-01-03 2001-01-03 Sealing multiple arrays of reaction vessels, each with rim flange and seal, generally simultaneously with a single closure member
EP02710520A EP1347829B1 (en) 2001-01-03 2002-01-02 Multiple vessel array
DE60229211T DE60229211D1 (en) 2001-01-03 2002-01-02 ARRAY FOR MULTIPLE CONTAINERS
PCT/NL2002/000002 WO2002053278A1 (en) 2001-01-03 2002-01-02 Multiple vessel array
AT02710520T ATE410226T1 (en) 2001-01-03 2002-01-02 ARRAY FOR MULTIPLE CONTAINER

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0100096A GB2370797A (en) 2001-01-03 2001-01-03 Sealing multiple arrays of reaction vessels, each with rim flange and seal, generally simultaneously with a single closure member

Publications (2)

Publication Number Publication Date
GB0100096D0 true GB0100096D0 (en) 2001-02-14
GB2370797A GB2370797A (en) 2002-07-10

Family

ID=9906182

Family Applications (1)

Application Number Title Priority Date Filing Date
GB0100096A Withdrawn GB2370797A (en) 2001-01-03 2001-01-03 Sealing multiple arrays of reaction vessels, each with rim flange and seal, generally simultaneously with a single closure member

Country Status (5)

Country Link
EP (1) EP1347829B1 (en)
AT (1) ATE410226T1 (en)
DE (1) DE60229211D1 (en)
GB (1) GB2370797A (en)
WO (1) WO2002053278A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2491908C (en) * 2002-08-02 2011-09-13 Avantium International B.V. An assembly and method for performing parallel chemical experiments, in particular crystallisation experiments
FR2877859B1 (en) * 2004-11-17 2007-02-16 Memos Soc Par Actions Simplifi REACTOR MULTIPUITS

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995027196A1 (en) * 1994-04-04 1995-10-12 Sanadi Ashok R Method and apparatus for preventing cross-contamination of multi-well test plates
US5785927A (en) 1996-10-24 1998-07-28 Eli Lilly And Company Vessel handling system useful for combinatorial chemistry
WO1999024160A1 (en) 1997-11-08 1999-05-20 Chemspeed, Ltd. Device for holding reaction vessels which can be thermally adjusted and agitated
CA2253164A1 (en) 1997-11-14 1999-05-14 Edward Michael Sioma Apparatus and method used in multiple, simultaneous synthesis of general compounds
US6306658B1 (en) * 1998-08-13 2001-10-23 Symyx Technologies Parallel reactor with internal sensing
US6132686A (en) 1999-05-28 2000-10-17 Mettler-Toledo Bohdan, Inc. Pressurized reaction block
CA2327419C (en) * 1999-12-15 2009-01-13 Uop Llc Combinatorial catalytic reactor

Also Published As

Publication number Publication date
WO2002053278A1 (en) 2002-07-11
WO2002053278A8 (en) 2002-11-14
EP1347829B1 (en) 2008-10-08
DE60229211D1 (en) 2008-11-20
EP1347829A2 (en) 2003-10-01
ATE410226T1 (en) 2008-10-15
GB2370797A (en) 2002-07-10

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)