FR74005E - Process for preparing coumarin derivatives with biological effect - Google Patents
Process for preparing coumarin derivatives with biological effectInfo
- Publication number
- FR74005E FR74005E FR49990A FR74005DA FR74005E FR 74005 E FR74005 E FR 74005E FR 49990 A FR49990 A FR 49990A FR 74005D A FR74005D A FR 74005DA FR 74005 E FR74005 E FR 74005E
- Authority
- FR
- France
- Prior art keywords
- biological effect
- coumarin derivatives
- acetone
- preparing coumarin
- hydroxycoumarin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000004071 biological effect Effects 0.000 title 1
- 150000001893 coumarin derivatives Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- VXIXUWQIVKSKSA-UHFFFAOYSA-N 4-hydroxycoumarin Chemical compound C1=CC=CC2=C1OC(=O)C=C2O VXIXUWQIVKSKSA-UHFFFAOYSA-N 0.000 abstract 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- ZABBFAHZPHMIJC-UHFFFAOYSA-N 1,1-Dibromopropan-2-one Chemical compound CC(=O)C(Br)Br ZABBFAHZPHMIJC-UHFFFAOYSA-N 0.000 abstract 2
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- CEQFOVLGLXCDCX-WUKNDPDISA-N methyl red Chemical compound C1=CC(N(C)C)=CC=C1\N=N\C1=CC=CC=C1C(O)=O CEQFOVLGLXCDCX-WUKNDPDISA-N 0.000 abstract 1
- 235000011118 potassium hydroxide Nutrition 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
- C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
- C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
- C07D311/48—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring with two such benzopyran radicals linked together by a carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Abstract
3,31 - Bis - 4 - hydroxycoumarinyl - acetone is prepared by condensing 4-hydroxycoumarin with an asymmetric dihaloacetone, e.g. dichloro-or dibromo-acetone. Examples are given in which the condensation takes place by refluxing dichloro- or dibromo-acetone with an aqueous suspension of 4-hydroxycoumarin which has been neutralized to Methyl Red by means of caustic potash. Specification 672,357 is referred to.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS305343X | 1950-11-13 | ||
| CH280975T | 1951-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR74005E true FR74005E (en) | 1961-03-08 |
Family
ID=25732045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR49990A Expired FR74005E (en) | 1950-11-13 | 1951-11-09 | Process for preparing coumarin derivatives with biological effect |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE507034A (en) |
| CH (1) | CH305343A (en) |
| FR (1) | FR74005E (en) |
| GB (1) | GB707668A (en) |
-
0
- BE BE507034D patent/BE507034A/xx unknown
-
1951
- 1951-10-31 CH CH305343D patent/CH305343A/en unknown
- 1951-11-08 GB GB26223/51A patent/GB707668A/en not_active Expired
- 1951-11-09 FR FR49990A patent/FR74005E/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BE507034A (en) | |
| CH305343A (en) | 1955-02-15 |
| GB707668A (en) | 1954-04-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR74005E (en) | Process for preparing coumarin derivatives with biological effect | |
| BE501677A (en) | PROCESS FOR THE PREPARATION OF OXAZOLINE DERIVATIVES. | |
| FR1032302A (en) | Process for the preparation of phtalyl derivatives of 2-sulfanilamido-1, 3, 4-thiodiazoles | |
| FR1042840A (en) | Process for the preparation of 1-azabicyclo-alkanol derivatives | |
| FR953127A (en) | Process for the preparation of cyanoethyl derivatives of 1, 3, 5-trimethylenetrisulfone | |
| FR887051A (en) | Process for the preparation of water-soluble flavanone glucosides | |
| BE501642R (en) | PROCESS FOR PREPARING DERIVATIVES OF HYDROXY-21-PREGNENE-5-OL-3-ONE-20. | |
| BE499681A (en) | PROCESS FOR THE PREPARATION OF NEW OXAZOLINE DERIVATIVES. | |
| FR1041556A (en) | Process for preparing coumarin derivatives with biological effect | |
| FR949274A (en) | Process for the preparation of polyallyl derivatives | |
| BE498749A (en) | PROCESS FOR PREPARATION OF NEW DERIVATIVES OF 4,4-DIAMINOSTILBENE-2,2'-DISULPHONIC ACID, THESE DERIVATIVES AND THEIR USE. | |
| FR1000525A (en) | Process for the preparation of water-soluble derivatives of hydroxylated coumarins | |
| BE497501A (en) | PROCESS FOR THE PREPARATION OF NEW DERIVATIVES OF BARBITURIC ACID. | |
| FR1047809A (en) | Process for the manufacture of organic salts of gamma-methylmercapto-alpha-amino-butyric acid, as well as of its n-acyl derivatives | |
| FR1028654A (en) | Process for the preparation of vanillin from sulphited waste water | |
| FR933545A (en) | Process for obtaining chlorinated organic derivatives by electromagnetic means | |
| FR1043692A (en) | Process for the preparation of d-threo-1-p-nitrophenyl-2-dichloracetamino-1, 3-propan-diol | |
| FR954224A (en) | Process for the purification of an aqueous sugar solution | |
| FR1029023A (en) | Process for the preparation of derivatives of diamino-1,4-benzenesulfonic acid-nu4 | |
| FR628033A (en) | Process for the preparation of novel urea derivatives of the formula | |
| FI26511A (en) | Process for the preparation of new derivatives of 4,4'-diaminostilbene disulfonic acid (2,2 ') | |
| FI26587A (en) | Process for the preparation of new derivatives of 4,4'-diaminostilbene disulfonic acid (2,2 ') | |
| FI26806A (en) | Process for the preparation of new derivatives of 4,4'-diaminostilbene disulfonic acid (2,2 ') | |
| CH289071A (en) | Process for the preparation of allo-1-p-nitrophenyl-2- (ortho-carboxybenzoyl) -amino-propanediol-1,3. | |
| BE501246A (en) | PROCESS FOR THE PREPARATION OF 2-SULFANILAMIDO-1,3,4-THIODIAZOLES PHTHALYL DERIVATIVES. |