FR3078637B1 - PARTICLE SORTING SYSTEM BY SIZE RANGE - Google Patents

PARTICLE SORTING SYSTEM BY SIZE RANGE Download PDF

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Publication number
FR3078637B1
FR3078637B1 FR1852121A FR1852121A FR3078637B1 FR 3078637 B1 FR3078637 B1 FR 3078637B1 FR 1852121 A FR1852121 A FR 1852121A FR 1852121 A FR1852121 A FR 1852121A FR 3078637 B1 FR3078637 B1 FR 3078637B1
Authority
FR
France
Prior art keywords
main
injection
alignment
size range
sorting system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1852121A
Other languages
French (fr)
Other versions
FR3078637A1 (en
Inventor
Eloise Pariset
Vincent Agache
Jean Berthier
Aurelie THUAIRE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR1852121A priority Critical patent/FR3078637B1/en
Publication of FR3078637A1 publication Critical patent/FR3078637A1/en
Application granted granted Critical
Publication of FR3078637B1 publication Critical patent/FR3078637B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1028—Sorting particles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Combined Means For Separation Of Solids (AREA)

Abstract

L'invention concerne un système de tri, par gamme de tailles, de particules contenues dans un fluide (F), ledit système comprenant : Une entrée orientée pour générer un flux dudit fluide suivant une direction principale d'injection, Un réseau périodique en deux dimensions de plusieurs piliers (Px) de formes et tailles identiques, Ledit réseau périodique étant défini par une maille en forme de parallélogramme de manière à former plusieurs alignements suivant deux directions d'alignement, une première direction d'alignement (Y) qui est perpendiculaire à ladite direction principale d'injection et une deuxième direction d'alignement qui forme un premier angle aigu (a1) non nul avec ladite direction principale d'injection, Chaque pilier du réseau de pilier présentant une forme adaptée pour définir au moins une surface de déviation dudit flux qui est orientée suivant une direction formant un deuxième angle aigu (a2) non nul avec ladite direction principale d'injection et opposé audit premier angle (a1) par rapport à ladite direction principale d'injection.The invention relates to a system for sorting, by range of sizes, of particles contained in a fluid (F), said system comprising: An inlet oriented to generate a flow of said fluid in a main injection direction, A periodic network in two dimensions of several pillars (Px) of identical shapes and sizes, Said periodic network being defined by a mesh in the form of a parallelogram so as to form several alignments in two alignment directions, a first alignment direction (Y) which is perpendicular to said main direction of injection and a second direction of alignment which forms a first non-zero acute angle (a1) with said main direction of injection, each pillar of the pillar network having a shape adapted to define at least one surface of deflection of said flow which is oriented in a direction forming a second non-zero acute angle (a2) with said main injection direction n and opposite to said first angle (a1) relative to said main injection direction.

FR1852121A 2018-03-12 2018-03-12 PARTICLE SORTING SYSTEM BY SIZE RANGE Expired - Fee Related FR3078637B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1852121A FR3078637B1 (en) 2018-03-12 2018-03-12 PARTICLE SORTING SYSTEM BY SIZE RANGE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1852121A FR3078637B1 (en) 2018-03-12 2018-03-12 PARTICLE SORTING SYSTEM BY SIZE RANGE
FR1852121 2018-03-12

Publications (2)

Publication Number Publication Date
FR3078637A1 FR3078637A1 (en) 2019-09-13
FR3078637B1 true FR3078637B1 (en) 2020-03-13

Family

ID=62751027

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1852121A Expired - Fee Related FR3078637B1 (en) 2018-03-12 2018-03-12 PARTICLE SORTING SYSTEM BY SIZE RANGE

Country Status (1)

Country Link
FR (1) FR3078637B1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3127810A1 (en) 2021-10-01 2023-04-07 Commissariat à l'Energie Atomique et aux Energies Alternatives Drop sorting process
CN118847237B (en) * 2024-07-19 2025-05-02 深圳市睿迈生物科技有限公司 Deterministic lateral displacement chip with non-uniform design parameters and design method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2341103T3 (en) * 2002-10-23 2010-06-15 The Trustees Of Princeton University CONTINUOUS SEPARATION PROCEDURE OF PARTICLES USING RETICULATES OF ASYMETRICALLY ALIGNED OBSTACLES REGARDING FIELDS.
EP2304414B1 (en) * 2008-07-24 2017-03-15 The Trustees of Princeton University Bump array device having asymmetric gaps for segregation of particles

Also Published As

Publication number Publication date
FR3078637A1 (en) 2019-09-13

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