FR3054963B1 - Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase - Google Patents
Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase Download PDFInfo
- Publication number
- FR3054963B1 FR3054963B1 FR1657690A FR1657690A FR3054963B1 FR 3054963 B1 FR3054963 B1 FR 3054963B1 FR 1657690 A FR1657690 A FR 1657690A FR 1657690 A FR1657690 A FR 1657690A FR 3054963 B1 FR3054963 B1 FR 3054963B1
- Authority
- FR
- France
- Prior art keywords
- purines
- deficit
- inhibitor
- treatment
- novo synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000055161 Adenylosuccinate lyases Human genes 0.000 title 1
- 101001131930 Homo sapiens Transcriptional activator protein Pur-beta Proteins 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 230000006735 deficit Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000003212 purines Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1657690A FR3054963B1 (fr) | 2016-08-10 | 2016-08-10 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
EP17764875.5A EP3496723A1 (fr) | 2016-08-10 | 2017-08-08 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
CA3033446A CA3033446A1 (fr) | 2016-08-10 | 2017-08-08 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
US16/324,454 US20190298722A1 (en) | 2016-08-10 | 2017-08-08 | Use of an inhibitor of the de novo synthesis of purines, in the treatment of adenylosuccinate lyase deficiency |
PCT/FR2017/052213 WO2018029430A1 (fr) | 2016-08-10 | 2017-08-08 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1657690A FR3054963B1 (fr) | 2016-08-10 | 2016-08-10 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
FR1657690 | 2016-08-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3054963A1 FR3054963A1 (fr) | 2018-02-16 |
FR3054963B1 true FR3054963B1 (fr) | 2018-09-14 |
Family
ID=57860942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1657690A Expired - Fee Related FR3054963B1 (fr) | 2016-08-10 | 2016-08-10 | Utilisation d'un inhibiteur de la synthese de novo des purines, dans le traitement du deficit en adenylosuccinate lyase |
Country Status (5)
Country | Link |
---|---|
US (1) | US20190298722A1 (fr) |
EP (1) | EP3496723A1 (fr) |
CA (1) | CA3033446A1 (fr) |
FR (1) | FR3054963B1 (fr) |
WO (1) | WO2018029430A1 (fr) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018059214A1 (fr) * | 2016-09-29 | 2018-04-05 | 广州君赫生物科技有限公司 | Composés affectant la synthèse de saicar, et applications |
US11517541B2 (en) | 2017-04-20 | 2022-12-06 | Geneheal Biotechnology Co., Ltd. | Applications of spermidine and its derivatives |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014067038A1 (fr) * | 2012-10-29 | 2014-05-08 | 广州百赫医疗信息科技有限公司 | Point repère, préparation et méthode de traitement de carence en adsl chez l'être humain |
WO2017033963A1 (fr) * | 2015-08-26 | 2017-03-02 | 株式会社スタージェン | Agent de renforcement de l'atp dans les cellules |
-
2016
- 2016-08-10 FR FR1657690A patent/FR3054963B1/fr not_active Expired - Fee Related
-
2017
- 2017-08-08 CA CA3033446A patent/CA3033446A1/fr not_active Abandoned
- 2017-08-08 EP EP17764875.5A patent/EP3496723A1/fr not_active Withdrawn
- 2017-08-08 US US16/324,454 patent/US20190298722A1/en not_active Abandoned
- 2017-08-08 WO PCT/FR2017/052213 patent/WO2018029430A1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US20190298722A1 (en) | 2019-10-03 |
FR3054963A1 (fr) | 2018-02-16 |
EP3496723A1 (fr) | 2019-06-19 |
CA3033446A1 (fr) | 2018-02-15 |
WO2018029430A1 (fr) | 2018-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 2 |
|
PLSC | Publication of the preliminary search report |
Effective date: 20180216 |
|
PLFP | Fee payment |
Year of fee payment: 3 |
|
PLFP | Fee payment |
Year of fee payment: 4 |
|
ST | Notification of lapse |
Effective date: 20210405 |