FR3017294B1 - LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY - Google Patents

LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY Download PDF

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Publication number
FR3017294B1
FR3017294B1 FR1450964A FR1450964A FR3017294B1 FR 3017294 B1 FR3017294 B1 FR 3017294B1 FR 1450964 A FR1450964 A FR 1450964A FR 1450964 A FR1450964 A FR 1450964A FR 3017294 B1 FR3017294 B1 FR 3017294B1
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FR
France
Prior art keywords
antibiotic
nanocapsules
lipid
therapy
lipid nanoparticles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1450964A
Other languages
French (fr)
Other versions
FR3017294A1 (en
Inventor
Amokrane Reghal
Gilles Potel
Jacqueline Caillon
Cedric Jacqueline
Karim Asehoune
Maud Gonnet
Thomas Perrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ATLANGRAM
Original Assignee
ATLANGRAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ATLANGRAM filed Critical ATLANGRAM
Priority to FR1450964A priority Critical patent/FR3017294B1/en
Priority to PCT/IB2015/050913 priority patent/WO2015118496A1/en
Publication of FR3017294A1 publication Critical patent/FR3017294A1/en
Application granted granted Critical
Publication of FR3017294B1 publication Critical patent/FR3017294B1/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nanotechnology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention se rapporte à des nanocapsules lipidiques comprenant un cœur lipidique liquide ou semi-liquide à température ambiante dans lequel est incorporé au moins un antibiotique, le cœur étant enveloppé d'une enveloppe lipidique solide à température ambiante, et à une composition pharmaceutique comprenant de telles nanocapsules pour traiter ou prévenir une infection bactérienne touchant une articulation, un os ou la peau. La présente invention porte également sur des dispositifs médicaux comprenant de telles nanocapsules ou composition pharmaceutiques.The present invention relates to lipid nanocapsules comprising a liquid or semi-liquid lipid core at ambient temperature in which at least one antibiotic is incorporated, the core being enveloped in a lipid envelope which is solid at ambient temperature, and to a pharmaceutical composition comprising such nanocapsules for treating or preventing bacterial infection affecting a joint, bone or skin. The present invention also relates to medical devices comprising such nanocapsules or pharmaceutical compositions.

FR1450964A 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY Active FR3017294B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1450964A FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY
PCT/IB2015/050913 WO2015118496A1 (en) 2014-02-07 2015-02-06 Lipid nanocapsules containing an antibiotic and therapeutic uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1450964A FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY

Publications (2)

Publication Number Publication Date
FR3017294A1 FR3017294A1 (en) 2015-08-14
FR3017294B1 true FR3017294B1 (en) 2021-10-01

Family

ID=50624776

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1450964A Active FR3017294B1 (en) 2014-02-07 2014-02-07 LIPID NANOPARTICLES INCLUDING AN ANTIBIOTIC AND THEIR USES IN THERAPY

Country Status (2)

Country Link
FR (1) FR3017294B1 (en)
WO (1) WO2015118496A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3679928A1 (en) 2019-01-08 2020-07-15 Atlangram Gel type pharmaceutical composition for treating/preventing an infection
CA3139942A1 (en) 2019-06-14 2020-12-17 Justyna NOWAKOWSKA Medicament and use thereof for treating bacterial infections involving biofilm
CN112263395B (en) * 2020-09-18 2021-12-14 浙江珍琦护理用品有限公司 Panty-shape diapers convenient to adjust size

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805761B1 (en) * 2000-03-02 2002-08-30 Mainelab LIPID NANOCAPSULES, METHOD OF PREPARATION AND USE AS A MEDICAMENT
FR2840532B1 (en) * 2002-06-11 2005-05-06 Ethypharm Sa FURENT LIPID NANOCAPSULES, PROCESS FOR THEIR PREPARATION AND USE AS VECTOR OF ACTIVE (S) PRINCIPLES
FR2916974B1 (en) 2007-06-11 2010-11-26 Univ Angers PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES
FR2916973B1 (en) 2007-06-11 2010-02-26 Univ Angers NANOCAPSULES WITH LIPIDIC HEAD CHARGED WITH HYDROSOLUBLE (S) OR HYDRODISPERSIBLE ACTIVE (S)
FR2939699B1 (en) 2008-12-12 2011-05-06 Univ Angers PROCESS FOR THE PREPARATION OF LIPID NANOPARTICLES
EP2678004A1 (en) * 2011-02-25 2014-01-01 Eydo Pharma Nanocapsulation of essential oils for preventing or curing infectious diseases alone or with an antibiotic

Also Published As

Publication number Publication date
WO2015118496A4 (en) 2015-10-08
WO2015118496A1 (en) 2015-08-13
FR3017294A1 (en) 2015-08-14

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