FR3008098B1 - AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY - Google Patents

AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY

Info

Publication number
FR3008098B1
FR3008098B1 FR1356636A FR1356636A FR3008098B1 FR 3008098 B1 FR3008098 B1 FR 3008098B1 FR 1356636 A FR1356636 A FR 1356636A FR 1356636 A FR1356636 A FR 1356636A FR 3008098 B1 FR3008098 B1 FR 3008098B1
Authority
FR
France
Prior art keywords
affinity chromatography
chromatography matrix
ligand density
reduced ligand
reduced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1356636A
Other languages
French (fr)
Other versions
FR3008098A1 (en
Inventor
Philippe Paolantonacci
Abdessatar Chtourou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR1356636A priority Critical patent/FR3008098B1/en
Application filed by LFB SA filed Critical LFB SA
Priority to AU2014285971A priority patent/AU2014285971A1/en
Priority to KR1020167003199A priority patent/KR20160029840A/en
Priority to PCT/FR2014/051734 priority patent/WO2015001277A1/en
Priority to PL14750552T priority patent/PL3016729T3/en
Priority to EP14750552.3A priority patent/EP3016729B1/en
Priority to TW103123198A priority patent/TW201509432A/en
Priority to JP2016522848A priority patent/JP2016532100A/en
Priority to CN201480038362.8A priority patent/CN105358228A/en
Priority to US14/902,716 priority patent/US10611826B2/en
Priority to ES14750552T priority patent/ES2793176T3/en
Priority to MX2016000063A priority patent/MX2016000063A/en
Priority to CA2916566A priority patent/CA2916566A1/en
Publication of FR3008098A1 publication Critical patent/FR3008098A1/en
Priority to IL243414A priority patent/IL243414A0/en
Application granted granted Critical
Publication of FR3008098B1 publication Critical patent/FR3008098B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
FR1356636A 2013-07-05 2013-07-05 AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY Active FR3008098B1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR1356636A FR3008098B1 (en) 2013-07-05 2013-07-05 AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY
ES14750552T ES2793176T3 (en) 2013-07-05 2014-07-04 Affinity Chromography Matrix
PCT/FR2014/051734 WO2015001277A1 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
PL14750552T PL3016729T3 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
EP14750552.3A EP3016729B1 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
TW103123198A TW201509432A (en) 2013-07-05 2014-07-04 Matrix of affinity chromatography
JP2016522848A JP2016532100A (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
CN201480038362.8A CN105358228A (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
AU2014285971A AU2014285971A1 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
KR1020167003199A KR20160029840A (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
MX2016000063A MX2016000063A (en) 2013-07-05 2014-07-04 Affinity chromatography matrix.
CA2916566A CA2916566A1 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
US14/902,716 US10611826B2 (en) 2013-07-05 2014-07-04 Affinity chromatography matrix
IL243414A IL243414A0 (en) 2013-07-05 2015-12-30 Affinity chromatography matrix

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1356636A FR3008098B1 (en) 2013-07-05 2013-07-05 AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY

Publications (2)

Publication Number Publication Date
FR3008098A1 FR3008098A1 (en) 2015-01-09
FR3008098B1 true FR3008098B1 (en) 2016-09-16

Family

ID=49212918

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1356636A Active FR3008098B1 (en) 2013-07-05 2013-07-05 AFFINITY CHROMATOGRAPHY MATRIX WITH REDUCED LIGAND DENSITY

Country Status (1)

Country Link
FR (1) FR3008098B1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3026950A1 (en) * 2014-10-09 2016-04-15 Lab Francais Du Fractionnement PROCESS FOR THE PREPARATION OF UNIVERSAL PLASMA
US10697982B2 (en) 2015-09-08 2020-06-30 Merck Patent Gmbh Methods of evaluating quality of a chromatography media which binds anti-A or anti-B antibodies
US10697983B2 (en) * 2015-09-08 2020-06-30 Merck Patent Gmbh Methods of evaluating quality of media suitable for removing anti-A or anti-B antibodies
US20170066839A1 (en) * 2015-09-08 2017-03-09 Merck Patent Gmbh Novel affinity chromatography media for removal of anti-a and/or anti-b antibodies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE464687B (en) * 1987-11-10 1991-06-03 Biocarb Ab PROCEDURES FOR PREPARING A GEL PRODUCT
US6686457B1 (en) * 1996-12-23 2004-02-03 Kurt Nilsson Material
AU2013200440B2 (en) * 2005-12-26 2016-03-31 Laboratoire Francais Du Fractionnement Et Des Biotechnologies Immunoglobulin G (IgG) concentrate depleted of anti-A and anti-B antibodies and of polyreactive IgGs
EP2556848A1 (en) * 2011-08-08 2013-02-13 Gambro Lundia AB Separation material comprising saccharide ligands
SE1200356A1 (en) * 2011-10-30 2013-05-01 Kurt Nilsson Polymer-based product and use

Also Published As

Publication number Publication date
FR3008098A1 (en) 2015-01-09

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