FR2970178B1 - PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE - Google Patents

PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE

Info

Publication number
FR2970178B1
FR2970178B1 FR1100060A FR1100060A FR2970178B1 FR 2970178 B1 FR2970178 B1 FR 2970178B1 FR 1100060 A FR1100060 A FR 1100060A FR 1100060 A FR1100060 A FR 1100060A FR 2970178 B1 FR2970178 B1 FR 2970178B1
Authority
FR
France
Prior art keywords
promoters
better tolerance
level delivery
specific liver
liver level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1100060A
Other languages
French (fr)
Other versions
FR2970178A1 (en
Inventor
Liliane Therese Jacquot
Jacques Paul Djian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AURELIE DJIAN, FR
Deborah Anna Djian Fr
JOYCE AMELIE DJIAN, FR
Laurence Leruste Fr
Liliane Therese Jacquot Fr
Nicolas Djian Fr
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR1100060A priority Critical patent/FR2970178B1/en
Priority to PCT/FR2012/000008 priority patent/WO2012093227A1/en
Publication of FR2970178A1 publication Critical patent/FR2970178A1/en
Application granted granted Critical
Publication of FR2970178B1 publication Critical patent/FR2970178B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
FR1100060A 2011-01-07 2011-01-07 PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE Expired - Fee Related FR2970178B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR1100060A FR2970178B1 (en) 2011-01-07 2011-01-07 PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE
PCT/FR2012/000008 WO2012093227A1 (en) 2011-01-07 2012-01-06 Prodrugs for dispensing a statin to the liver

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1100060A FR2970178B1 (en) 2011-01-07 2011-01-07 PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE

Publications (2)

Publication Number Publication Date
FR2970178A1 FR2970178A1 (en) 2012-07-13
FR2970178B1 true FR2970178B1 (en) 2014-06-20

Family

ID=43984138

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1100060A Expired - Fee Related FR2970178B1 (en) 2011-01-07 2011-01-07 PROMOTERS FOR SPECIFIC LIVER LEVEL DELIVERY AND BETTER TOLERANCE

Country Status (2)

Country Link
FR (1) FR2970178B1 (en)
WO (1) WO2012093227A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115025242B (en) * 2022-05-19 2023-10-20 南开大学 Statin prodrug and statin targeted delivery system as well as preparation methods and applications thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0204129D0 (en) * 2002-02-21 2002-04-10 Novartis Ag Process for the manufacture of organic compounds
CA2611920C (en) * 2005-06-24 2015-05-05 Lek Pharmaceuticals D.D. Process for preparing pure amorphous rosuvastatin calcium
WO2008075165A1 (en) * 2006-12-19 2008-06-26 Pfizer Products Inc. Novel process for the synthesis of [r-(r*, r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid or a pharmaceutically acceptable salt thereof
WO2009009152A1 (en) * 2007-07-12 2009-01-15 Teva Pharmaceutical Industries Ltd. Rosuvastatin intermediates and their preparation
KR100813666B1 (en) * 2007-10-23 2008-03-14 (주)에이에스텍 Prodrug of atrovastatin by cholesterol's synthesis inhibitors

Also Published As

Publication number Publication date
FR2970178A1 (en) 2012-07-13
WO2012093227A1 (en) 2012-07-12

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Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 5

TQ Partial transmission of property

Owner name: LILIANE THERESE JACQUOT, FR

Effective date: 20150520

Owner name: NICOLAS DJIAN, FR

Effective date: 20150520

Owner name: JOYCE AMELIE DJIAN, FR

Effective date: 20150520

Owner name: AURELIE DJIAN, FR

Effective date: 20150520

Owner name: LAURENCE LERUSTE, FR

Effective date: 20150520

Owner name: DEBORAH ANNA DJIAN, FR

Effective date: 20150520

PLFP Fee payment

Year of fee payment: 6

ST Notification of lapse

Effective date: 20170929