FR2969613B1 - NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE - Google Patents
NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USEInfo
- Publication number
- FR2969613B1 FR2969613B1 FR1061197A FR1061197A FR2969613B1 FR 2969613 B1 FR2969613 B1 FR 2969613B1 FR 1061197 A FR1061197 A FR 1061197A FR 1061197 A FR1061197 A FR 1061197A FR 2969613 B1 FR2969613 B1 FR 2969613B1
- Authority
- FR
- France
- Prior art keywords
- pyrimido
- pyrimidin
- tetrahydro
- derivatives
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1061197A FR2969613B1 (en) | 2010-12-23 | 2010-12-23 | NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE |
ES11799724.7T ES2531465T3 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, their preparation and pharmaceutical use |
SI201130400T SI2655375T1 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
DK11799724.7T DK2655375T3 (en) | 2010-12-23 | 2011-12-22 | PYRIMIDINON DERIVATIVES, PREPARATION AND PHARMACEUTICAL USE THEREOF |
HUE11799724A HUE024504T2 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
PT11799724T PT2655375E (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
PL11799724T PL2655375T3 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
US13/996,866 US8815853B2 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
EP11799724.7A EP2655375B1 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
PCT/EP2011/073874 WO2012085244A1 (en) | 2010-12-23 | 2011-12-22 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
HRP20150235TT HRP20150235T1 (en) | 2010-12-23 | 2015-03-02 | Pyrimidinone derivatives, preparation thereof and pharmaceutical use thereof |
CY20151100220T CY1116100T1 (en) | 2010-12-23 | 2015-03-03 | PYRIMIDINONE PRODUCTS, THEIR PREPARATION AND THE PHARMACEUTICAL USE |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1061197A FR2969613B1 (en) | 2010-12-23 | 2010-12-23 | NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2969613A1 FR2969613A1 (en) | 2012-06-29 |
FR2969613B1 true FR2969613B1 (en) | 2013-02-08 |
Family
ID=44174648
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1061197A Expired - Fee Related FR2969613B1 (en) | 2010-12-23 | 2010-12-23 | NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2969613B1 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201321127D0 (en) * | 2013-11-29 | 2014-01-15 | Velgene Biotechnology | Compound with Anti-cancer properties |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ520300A (en) * | 2000-01-24 | 2004-05-28 | Kinacia Pty Ltd | Morpholino-substituted pyridopyrimidine, quinolone and benzopyranone derivatives that inhibit the enzyme phosphoinositide (PI) 3-kinase |
US7598377B2 (en) * | 2002-08-16 | 2009-10-06 | Astrazeneca Ab | Inhibition of phosphoinositide 3-kinase β |
WO2008148074A2 (en) * | 2007-05-24 | 2008-12-04 | Research Foundation Of State University Of New York | Inhibitors of mtor and methods of treatment using same |
AU2009206804A1 (en) * | 2008-01-25 | 2009-07-30 | Astrazeneca Ab | Enantiomerically pure (-) 2-[1-(7-methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino]benzoic acid, its use in medical therapy, and a pharmaceutical composition comprising it - 026 |
AU2010267815B2 (en) * | 2009-07-02 | 2015-07-16 | Sanofi | Novel 1,2,3,4-tetrahydro-pyrimido(1,2-a)pyrimidin-6-one derivatives, preparation thereof, and pharmaceutical use thereof |
-
2010
- 2010-12-23 FR FR1061197A patent/FR2969613B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2969613A1 (en) | 2012-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FR2992314B1 (en) | NOVEL 2,3-DIHYDRO-1H-IMIDAZO {1,2-A} PYRIMIDIN-5-ONE AND 1,2,3,4-TETRAHYDRO-PYRIMIDO {1,2-A} PYRIMIDIN-6-ONE DERIVATIVES COMPRISING A SUBSTITUTED MORPHOLINE, THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | |
FR2954317B1 (en) | NOVEL PHENOLIC DERIVATIVES, AND THEIR PHARMACEUTICAL OR COSMETIC USE | |
FR2954315B1 (en) | NOVEL PHENOLIC DERIVATIVES, AND THEIR PHARMACEUTICAL OR COSMETIC USE | |
FR2982261B1 (en) | NOVEL AMIDES, AND THEIR PHARMACEUTICAL OR COSMETIC USE | |
FR2960875B1 (en) | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
FR2963007B1 (en) | ANTICANCER DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
BR112013015592A8 (en) | bicyclo [3.2.1] -octylamide derivatives and uses thereof | |
FR2962437B1 (en) | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION | |
FR2945534B1 (en) | CYCLOPENTAL [c] PYRROLE-2-CARBOXYLATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
FR2986002B1 (en) | NOVEL INDOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
FR2948568B1 (en) | PHARMACEUTICAL FORMULATION | |
CO7000778A2 (en) | Pyrazolopyridine derivatives, their preparation procedure and therapeutic use | |
GT201200303A (en) | PHARMACEUTICAL FORMULATIONS | |
BR112012032260A2 (en) | 2-oxo-1,3-dioxolane-4-carboxylic acid esters, their preparation and use | |
CO6870037A2 (en) | Phenyl-3-aza-bicyclo [3,1,0] hex-3-yl-methanones and their use as a medicine | |
FR2953520B1 (en) | DIPHENYL-PYRAZOLOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
IL217293A0 (en) | NOVEL 1,2,3,4 - TETRAHYDROPYRIMIDO {1,2-a} PYRIMIDIN - 6 - ONE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF | |
FR2958157B1 (en) | COSMETIC AND PHARMACEUTICAL COMPOSITION COMPRISING N-ACETYL-GLUCOSAMINE-6-PHOSPHATE | |
FR2952934B1 (en) | PYRIDINO-PYRIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | |
EP3006050A4 (en) | Low molecular weight polyethylene glycol drug conjugates having improved drug biological activity | |
FR2954943B1 (en) | ARYLSULFONAMIDE PYRIDINO-PYRIDINONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | |
BR112013017267A2 (en) | liposome formulation, suspension and pharmaceutical composition | |
FR2955109B1 (en) | 5-OXO-5,8-DIHYDRO-PYRIDO [2,3-D] PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | |
FR2960876B1 (en) | 3,4-DIHYDROPYRROLO [1,2-A] PYRAZINE-2,8 (1H) -DICARBOXAMIDE DERIVATIVES FOR THEIR PREPARATION AND THEIR THERAPEUTIC USE. | |
FR2986232B1 (en) | BICYCLIC HETEROCYCLIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 6 |
|
PLFP | Fee payment |
Year of fee payment: 7 |
|
PLFP | Fee payment |
Year of fee payment: 8 |
|
PLFP | Fee payment |
Year of fee payment: 9 |
|
ST | Notification of lapse |
Effective date: 20200910 |