FR2959129B1 - Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations - Google Patents

Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations

Info

Publication number
FR2959129B1
FR2959129B1 FR1053031A FR1053031A FR2959129B1 FR 2959129 B1 FR2959129 B1 FR 2959129B1 FR 1053031 A FR1053031 A FR 1053031A FR 1053031 A FR1053031 A FR 1053031A FR 2959129 B1 FR2959129 B1 FR 2959129B1
Authority
FR
France
Prior art keywords
phenylbutyrate
sodium
particles
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR1053031A
Other languages
English (en)
Other versions
FR2959129A1 (fr
Inventor
Estelle Foucher
Herve Brochart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LUCANE PHARMA
Original Assignee
LUCANE PHARMA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LUCANE PHARMA filed Critical LUCANE PHARMA
Priority to FR1053031A priority Critical patent/FR2959129B1/fr
Publication of FR2959129A1 publication Critical patent/FR2959129A1/fr
Application granted granted Critical
Publication of FR2959129B1 publication Critical patent/FR2959129B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR1053031A 2010-04-21 2010-04-21 Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations Active FR2959129B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR1053031A FR2959129B1 (fr) 2010-04-21 2010-04-21 Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1053031A FR2959129B1 (fr) 2010-04-21 2010-04-21 Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations

Publications (2)

Publication Number Publication Date
FR2959129A1 FR2959129A1 (fr) 2011-10-28
FR2959129B1 true FR2959129B1 (fr) 2013-02-01

Family

ID=42790931

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1053031A Active FR2959129B1 (fr) 2010-04-21 2010-04-21 Particules comprenant du 4-phenylbutyrate de sodium, procede de preparation et utilisations

Country Status (1)

Country Link
FR (1) FR2959129B1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11154521B2 (en) 2016-03-15 2021-10-26 Acer Therapeutics Inc. Palatable compositions including sodium phenylbutyrate and uses thereof

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2599477A1 (fr) * 2011-11-30 2013-06-05 Lunamed AG Formulation à libération prolongée d'acide 4-phénylbutyrique
US20210130480A1 (en) * 2017-08-22 2021-05-06 Regeneron Pharmaceuticals, Inc. Methods of treating urea cycle disorders by interfering with glucagon receptor signaling

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1291015A1 (fr) * 2001-09-10 2003-03-12 Lunamed AG Compositions à libération prolongée d'un agent actif
US20040152784A1 (en) * 2002-07-23 2004-08-05 Special Products Limited Pharmaceutical composition and method for treatment of a urea cycle deficiency or sickle-cell anaemia
JP2006515320A (ja) * 2002-12-31 2006-05-25 ラリー エル オーグスバーガー 活性クッション性成分を含有する医薬品剤形の製造方法
EP1799759A1 (fr) * 2004-08-30 2007-06-27 Lunamed Inc. Formulations a liberation controlee d'acide 4-phenylbutyrique utilisees dans des traitements

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11154521B2 (en) 2016-03-15 2021-10-26 Acer Therapeutics Inc. Palatable compositions including sodium phenylbutyrate and uses thereof
US11433041B2 (en) 2016-03-15 2022-09-06 Acer Therapeutics Inc. Palatable compositions including sodium phenylbutyrate and uses thereof

Also Published As

Publication number Publication date
FR2959129A1 (fr) 2011-10-28

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