FR2949467B1 - NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF - Google Patents

NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF

Info

Publication number
FR2949467B1
FR2949467B1 FR0956013A FR0956013A FR2949467B1 FR 2949467 B1 FR2949467 B1 FR 2949467B1 FR 0956013 A FR0956013 A FR 0956013A FR 0956013 A FR0956013 A FR 0956013A FR 2949467 B1 FR2949467 B1 FR 2949467B1
Authority
FR
France
Prior art keywords
tetrahydroindolizine
hsp90
novel
compositions containing
containing same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0956013A
Other languages
French (fr)
Other versions
FR2949467A1 (en
Inventor
Luc Bertin
Patrick Mailliet
Herve Minoux
Jean Marie Ruxer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0956013A priority Critical patent/FR2949467B1/en
Priority to ARP100103218A priority patent/AR078258A1/en
Priority to PCT/FR2010/051833 priority patent/WO2011027081A2/en
Publication of FR2949467A1 publication Critical patent/FR2949467A1/en
Application granted granted Critical
Publication of FR2949467B1 publication Critical patent/FR2949467B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0956013A 2009-09-03 2009-09-03 NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF Expired - Fee Related FR2949467B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0956013A FR2949467B1 (en) 2009-09-03 2009-09-03 NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF
ARP100103218A AR078258A1 (en) 2009-09-03 2010-09-02 DERIVATIVES OF 5,6,7,8-TETRAHYDROINDOLIZINE AS INHIBITORS OF HSP90, COMPOSITIONS THAT CONTAIN THEM AND USE
PCT/FR2010/051833 WO2011027081A2 (en) 2009-09-03 2010-09-03 Novel derivatives of 5,6,7,8-tetrahydroindolizine inhibiting hsp90, compositions containing same, and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0956013A FR2949467B1 (en) 2009-09-03 2009-09-03 NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF

Publications (2)

Publication Number Publication Date
FR2949467A1 FR2949467A1 (en) 2011-03-04
FR2949467B1 true FR2949467B1 (en) 2011-11-25

Family

ID=42115389

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0956013A Expired - Fee Related FR2949467B1 (en) 2009-09-03 2009-09-03 NOVEL 5,6,7,8-TETRAHYDROINDOLIZINE DERIVATIVES INHIBITORS OF HSP90, COMPOSITIONS CONTAINING SAME AND USE THEREOF

Country Status (3)

Country Link
AR (1) AR078258A1 (en)
FR (1) FR2949467B1 (en)
WO (1) WO2011027081A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240109895A1 (en) * 2020-12-29 2024-04-04 Shanghai Haiyan Pharmaceutical Technology Co., Ltd. Oxaspiro substituted pyrrolopyrazole derivative, intermediate thereof, and preparation method therefor

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Publication number Publication date
WO2011027081A3 (en) 2011-05-12
AR078258A1 (en) 2011-10-26
WO2011027081A2 (en) 2011-03-10
FR2949467A1 (en) 2011-03-04

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