FR2943060B1 - Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications - Google Patents

Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Info

Publication number
FR2943060B1
FR2943060B1 FR0901193A FR0901193A FR2943060B1 FR 2943060 B1 FR2943060 B1 FR 2943060B1 FR 0901193 A FR0901193 A FR 0901193A FR 0901193 A FR0901193 A FR 0901193A FR 2943060 B1 FR2943060 B1 FR 2943060B1
Authority
FR
France
Prior art keywords
applications
processes
preparation
metal ion
chelating agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0901193A
Other languages
English (en)
French (fr)
Other versions
FR2943060A1 (fr
Inventor
Pascale Delangle
Christelle Gateau
Anais Pujol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0901193A priority Critical patent/FR2943060B1/fr
Priority to JP2011553486A priority patent/JP5709765B2/ja
Priority to EP10712452A priority patent/EP2406238A1/fr
Priority to PCT/FR2010/000202 priority patent/WO2010103204A1/fr
Priority to EP15183767.1A priority patent/EP2982669B1/fr
Publication of FR2943060A1 publication Critical patent/FR2943060A1/fr
Application granted granted Critical
Publication of FR2943060B1 publication Critical patent/FR2943060B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR0901193A 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications Active FR2943060B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0901193A FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
JP2011553486A JP5709765B2 (ja) 2009-03-13 2010-03-11 金属イオンキレート剤、それらの製造方法およびそれらの使用
EP10712452A EP2406238A1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
PCT/FR2010/000202 WO2010103204A1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
EP15183767.1A EP2982669B1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0901193A FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Publications (2)

Publication Number Publication Date
FR2943060A1 FR2943060A1 (fr) 2010-09-17
FR2943060B1 true FR2943060B1 (fr) 2013-01-04

Family

ID=41130312

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0901193A Active FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Country Status (4)

Country Link
EP (2) EP2982669B1 (enExample)
JP (1) JP5709765B2 (enExample)
FR (1) FR2943060B1 (enExample)
WO (1) WO2010103204A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3640332A1 (en) 2011-08-29 2020-04-22 Ionis Pharmaceuticals, Inc. Oligomer-conjugate complexes and their use
CA2921162A1 (en) 2013-05-01 2014-11-06 Ionis Pharmaceuticals, Inc. Conjugated antisense compounds and their use
US10280423B2 (en) 2014-05-01 2019-05-07 Ionis Pharmaceuticals, Inc. Compositions and methods for modulating complement factor B expression
MX382230B (es) 2014-05-01 2025-03-13 Ionis Pharmaceuticals Inc Composiciones y metodos para modular la expresion de similar a la angiopoyetina tipo 3.
EP3370708A4 (en) 2015-11-06 2019-06-26 Ionis Pharmaceuticals, Inc. MODULATION OF APOLIPOPROTEIN (A) EXPRESSION
KR20190065341A (ko) 2016-10-06 2019-06-11 아이오니스 파마수티컬즈, 인코포레이티드 올리고머 화합물들의 접합 방법
CN111909238B (zh) * 2017-06-29 2022-04-08 安徽省农业科学院农产品加工研究所 一种含有Ser-Cys的高锌螯合活性锌螯合肽及其应用
KR20260051422A (ko) * 2023-08-31 2026-04-16 고꾸리쯔 다이가꾸호우징 도쿄노우코우다이가쿠 단백질 폴딩제, 화합물, 단백질 폴딩 방법, 의약 조성물 및 전이 금속에 의한 세포 독성 억제제
CN118715208A (zh) * 2023-10-20 2024-09-27 广东工业大学 治疗威尔逊氏病的特异性四齿铜螯合剂

Also Published As

Publication number Publication date
JP2012520271A (ja) 2012-09-06
EP2406238A1 (fr) 2012-01-18
EP2982669B1 (fr) 2017-05-10
WO2010103204A1 (fr) 2010-09-16
EP2982669A1 (fr) 2016-02-10
FR2943060A1 (fr) 2010-09-17
JP5709765B2 (ja) 2015-04-30

Similar Documents

Publication Publication Date Title
EP2470290A4 (en) ION EXCHANGE MEMBRANES
EP2688841A4 (en) AMMONIA SYNTHESIS USING LITHIUMION LEADING MEMBRANES
EP2561540A4 (en) IMPROVED ION SOURCE
EP2420310A4 (en) ION EXCHANGE MEMBRANE AND MANUFACTURING METHOD THEREFOR
GB2456853B (en) Metal treatment
BRPI0819294A2 (pt) Método de produção de artigo revestido incluindo tratamento de feixe de íon de película protetora de óxido de metal
EP2692782A4 (en) ION EXCHANGE MEMBRANE
GB2478093B (en) Improved automated trading system
GB201209106D0 (en) Ion trap for cooling ions
EP2606954A4 (en) ION EXCHANGE MEMBRANE AND MANUFACTURING METHOD THEREFOR
BRPI0818660A2 (pt) ortofosfato de ferro(iii) para acumuladores de íon li
EP2732501A4 (en) COMPOSITIONS COMPRISING A NANOSCALANT IONIC LIQUID MATERIAL AND METHOD AND APPLICATIONS THEREFOR
TWI371055B (en) Ion implanter
EP1923359A4 (en) FLUID AND MANUFACTURING METHOD THEREFOR
IT1397774B1 (it) Ferro da stiro.
EP2034546A4 (en) ION CONDUCTOR
ZA201103315B (en) Solubilizer for metal ions
WO2013187971A3 (en) Macrocycles
EP2113517A4 (en) COMPLEXES WITH ANGIOSTATIN AND FRAGMENTS THEREOF, METHOD FOR THE PRODUCTION OF PREPARATIONS THEREOF AND USES THEREOF
ZA200904268B (en) Metal formulations
EP2252635A4 (en) MODIFIED CARRAGEEN BY ION EXCHANGE PROCESS
FR2960034B1 (fr) Piece en metal coule et procede de coulee de metal
EP2664333A4 (en) POLYMIC IRON ROBILIZER
GB0723984D0 (en) Differential ion generator
EP2625305A4 (en) ION BEAM DISTRIBUTION

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15

PLFP Fee payment

Year of fee payment: 16

PLFP Fee payment

Year of fee payment: 17