FR2943060B1 - Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications - Google Patents

Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Info

Publication number
FR2943060B1
FR2943060B1 FR0901193A FR0901193A FR2943060B1 FR 2943060 B1 FR2943060 B1 FR 2943060B1 FR 0901193 A FR0901193 A FR 0901193A FR 0901193 A FR0901193 A FR 0901193A FR 2943060 B1 FR2943060 B1 FR 2943060B1
Authority
FR
France
Prior art keywords
applications
processes
preparation
metal ion
chelating agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0901193A
Other languages
English (en)
French (fr)
Other versions
FR2943060A1 (fr
Inventor
Pascale Delangle
Christelle Gateau
Anais Pujol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR0901193A priority Critical patent/FR2943060B1/fr
Priority to EP15183767.1A priority patent/EP2982669B1/fr
Priority to PCT/FR2010/000202 priority patent/WO2010103204A1/fr
Priority to JP2011553486A priority patent/JP5709765B2/ja
Priority to EP10712452A priority patent/EP2406238A1/fr
Publication of FR2943060A1 publication Critical patent/FR2943060A1/fr
Application granted granted Critical
Publication of FR2943060B1 publication Critical patent/FR2943060B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR0901193A 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications Active FR2943060B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0901193A FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
EP15183767.1A EP2982669B1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
PCT/FR2010/000202 WO2010103204A1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
JP2011553486A JP5709765B2 (ja) 2009-03-13 2010-03-11 金属イオンキレート剤、それらの製造方法およびそれらの使用
EP10712452A EP2406238A1 (fr) 2009-03-13 2010-03-11 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0901193A FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Publications (2)

Publication Number Publication Date
FR2943060A1 FR2943060A1 (fr) 2010-09-17
FR2943060B1 true FR2943060B1 (fr) 2013-01-04

Family

ID=41130312

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0901193A Active FR2943060B1 (fr) 2009-03-13 2009-03-13 Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications

Country Status (4)

Country Link
EP (2) EP2406238A1 (enExample)
JP (1) JP5709765B2 (enExample)
FR (1) FR2943060B1 (enExample)
WO (1) WO2010103204A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2751270B1 (en) 2011-08-29 2018-08-22 Ionis Pharmaceuticals, Inc. Oligomer-conjugate complexes and their use
KR102482890B1 (ko) 2013-05-01 2022-12-30 아이오니스 파마수티컬즈, 인코포레이티드 아포지질단백질 (a) 발현을 조절하는 조성물 및 방법
SI3137605T1 (sl) 2014-05-01 2021-02-26 Ionis Pharmaceuticals, Inc. Sestavki in metode za modulacijo ekspresije angiopoetin 3-podobnega
PE20170010A1 (es) 2014-05-01 2017-03-04 Ionis Pharmaceuticals Inc Composiciones y metodos para modular la expresion del factor b del complemento
CA2999341A1 (en) 2015-11-06 2017-05-11 Ionis Pharmaceuticals, Inc. Modulating apolipoprotein (a) expression
CN109661233A (zh) 2016-10-06 2019-04-19 Ionis 制药公司 缀合低聚化合物的方法
CN111909238B (zh) * 2017-06-29 2022-04-08 安徽省农业科学院农产品加工研究所 一种含有Ser-Cys的高锌螯合活性锌螯合肽及其应用
WO2025047827A1 (ja) * 2023-08-31 2025-03-06 国立大学法人東京農工大学 タンパク質フォールディング剤、化合物、タンパク質フォールディング方法、医薬組成物、及び遷移金属による細胞毒性の抑制剤
WO2025081478A1 (en) * 2023-10-20 2025-04-24 Guangdong University Of Technology Specific tetradentate copper chelators for the treatment of wilson's disease

Also Published As

Publication number Publication date
EP2982669A1 (fr) 2016-02-10
JP2012520271A (ja) 2012-09-06
FR2943060A1 (fr) 2010-09-17
WO2010103204A1 (fr) 2010-09-16
JP5709765B2 (ja) 2015-04-30
EP2406238A1 (fr) 2012-01-18
EP2982669B1 (fr) 2017-05-10

Similar Documents

Publication Publication Date Title
FR2943060B1 (fr) Agents chelatants d'ions metalliques, leurs procedes de preparation et leurs applications
EP2470290A4 (en) ION EXCHANGE MEMBRANES
EP2688841A4 (en) AMMONIA SYNTHESIS USING LITHIUMION LEADING MEMBRANES
EP2420310A4 (en) ION EXCHANGE MEMBRANE AND MANUFACTURING METHOD THEREFOR
GB2456853B (en) Metal treatment
EP2692782A4 (en) ION EXCHANGE MEMBRANE
EP2145032A4 (en) COMPOSITIONS WITH HARDANTS AND GLUCONATE AND METHOD THEREFORE FOR REDUCING CORROSIONS AND WEAKNESSES
GB2478093B (en) Improved automated trading system
GB201105261D0 (en) Ion trap for cooling ions
GB0900460D0 (en) Linear ion trap
TWI371055B (en) Ion implanter
PL2353259T3 (pl) Przetwarzanie wiadomości
EP1923359A4 (en) FLUID AND MANUFACTURING METHOD THEREFOR
FR2949600B1 (fr) Circuit d'alignement de grille antidiffusion
ZA201103315B (en) Solubilizer for metal ions
WO2013187971A3 (en) Macrocycles
ZA200904268B (en) Metal formulations
FR2960034B1 (fr) Piece en metal coule et procede de coulee de metal
EP2664333A4 (en) POLYMIC IRON ROBILIZER
EP2067774A4 (en) MEANS FOR INHIBITING PERCHLORIC ACID
EP2625305A4 (en) ION BEAM DISTRIBUTION
BRPI0818676A2 (pt) Método de produção de ferro reduzido direto
BR112014016497A2 (pt) calmangafodipir, um novo elemento químico e outros complexos de metal misturados, métodos de preparação, composições e métodos de tratamento
GB0611460D0 (en) Ion beams in an ion implanter
EP2055671A4 (en) METAL PHOSPHATE

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 7

PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15

PLFP Fee payment

Year of fee payment: 16

PLFP Fee payment

Year of fee payment: 17