FR2936243B1 - PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS - Google Patents

PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS

Info

Publication number
FR2936243B1
FR2936243B1 FR0805169A FR0805169A FR2936243B1 FR 2936243 B1 FR2936243 B1 FR 2936243B1 FR 0805169 A FR0805169 A FR 0805169A FR 0805169 A FR0805169 A FR 0805169A FR 2936243 B1 FR2936243 B1 FR 2936243B1
Authority
FR
France
Prior art keywords
preparation
adamantyl compounds
adamantyl
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0805169A
Other languages
French (fr)
Other versions
FR2936243A1 (en
Inventor
Vivien Henryon
Jerome Monbrun
Michel Casado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finorga SAS
Original Assignee
Finorga SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finorga SAS filed Critical Finorga SAS
Priority to FR0805169A priority Critical patent/FR2936243B1/en
Priority to PCT/IB2009/006919 priority patent/WO2010032129A1/en
Publication of FR2936243A1 publication Critical patent/FR2936243A1/en
Application granted granted Critical
Publication of FR2936243B1 publication Critical patent/FR2936243B1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
    • C07C235/74—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/18—Preparation of carboxylic acid esters by conversion of a group containing nitrogen into an ester group
    • C07C67/20—Preparation of carboxylic acid esters by conversion of a group containing nitrogen into an ester group from amides or lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
FR0805169A 2008-09-19 2008-09-19 PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS Expired - Fee Related FR2936243B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR0805169A FR2936243B1 (en) 2008-09-19 2008-09-19 PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS
PCT/IB2009/006919 WO2010032129A1 (en) 2008-09-19 2009-09-21 Method for producing adamantyl compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0805169A FR2936243B1 (en) 2008-09-19 2008-09-19 PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS

Publications (2)

Publication Number Publication Date
FR2936243A1 FR2936243A1 (en) 2010-03-26
FR2936243B1 true FR2936243B1 (en) 2010-09-24

Family

ID=40499174

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0805169A Expired - Fee Related FR2936243B1 (en) 2008-09-19 2008-09-19 PROCESS FOR THE PREPARATION OF ADAMANTYL COMPOUNDS

Country Status (2)

Country Link
FR (1) FR2936243B1 (en)
WO (1) WO2010032129A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013179297A1 (en) * 2012-05-30 2013-12-05 Rao Davuluri Ramamohan Process for preparation of (1s, 3s, 5s)-2-[(2s)-2-amino-2-(3-hydroxy-1-adamantyl) acetyl]-2-azabicyclo [3.1.0] hexane-3-carbonitrile
CN103265473A (en) * 2013-06-04 2013-08-28 上海同昌生物医药科技有限公司 Method for producing saxagliptin
CN103304406A (en) * 2013-06-08 2013-09-18 苏州永健生物医药有限公司 Preparation method of 2-(1-adamantly) glyoxylic acid
CN113666846B (en) * 2021-08-31 2023-06-27 济南立德医药技术有限公司 Synthesis method of saxagliptin intermediate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7205432B2 (en) * 2005-05-31 2007-04-17 Kemfine Oy Process for the preparation of adamantane derivatives

Also Published As

Publication number Publication date
FR2936243A1 (en) 2010-03-26
WO2010032129A1 (en) 2010-03-25

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20120531