FR2892423B1 - Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives - Google Patents

Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives

Info

Publication number
FR2892423B1
FR2892423B1 FR0510748A FR0510748A FR2892423B1 FR 2892423 B1 FR2892423 B1 FR 2892423B1 FR 0510748 A FR0510748 A FR 0510748A FR 0510748 A FR0510748 A FR 0510748A FR 2892423 B1 FR2892423 B1 FR 2892423B1
Authority
FR
France
Prior art keywords
stable
cell lines
biologically active
recombinant cell
active proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0510748A
Other languages
English (en)
Other versions
FR2892423A1 (fr
Inventor
Patrick Mollat
Corinne Gillard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galapagos SAS
Original Assignee
Galapagos SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galapagos SAS filed Critical Galapagos SAS
Priority to FR0510748A priority Critical patent/FR2892423B1/fr
Priority to JP2008536061A priority patent/JP5061112B2/ja
Priority to EP06829918A priority patent/EP1960514A1/fr
Priority to US12/090,793 priority patent/US8158417B2/en
Priority to PCT/EP2006/067620 priority patent/WO2007045690A1/fr
Publication of FR2892423A1 publication Critical patent/FR2892423A1/fr
Application granted granted Critical
Publication of FR2892423B1 publication Critical patent/FR2892423B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
FR0510748A 2005-10-21 2005-10-21 Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives Expired - Fee Related FR2892423B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0510748A FR2892423B1 (fr) 2005-10-21 2005-10-21 Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives
JP2008536061A JP5061112B2 (ja) 2005-10-21 2006-10-20 生物学的に活性なｄｋｋ１タンパク質の安定かつ高レベルの生産のための組み換えセルライン
EP06829918A EP1960514A1 (fr) 2005-10-21 2006-10-20 Lignées cellulaires recombinantes pour la production stable et à un niveau élevé de protéine dkk1 biologiquement active
US12/090,793 US8158417B2 (en) 2005-10-21 2006-10-20 Recombinant cell lines for the stable and high-level production of biologically active Dkk1 protein
PCT/EP2006/067620 WO2007045690A1 (fr) 2005-10-21 2006-10-20 Lignées cellulaires recombinantes pour la production stable et à un niveau élevé de protéine dkk1 biologiquement active

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0510748A FR2892423B1 (fr) 2005-10-21 2005-10-21 Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives

Publications (2)

Publication Number Publication Date
FR2892423A1 FR2892423A1 (fr) 2007-04-27
FR2892423B1 true FR2892423B1 (fr) 2012-08-24

Family

ID=36609332

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0510748A Expired - Fee Related FR2892423B1 (fr) 2005-10-21 2005-10-21 Lignees cellulaires recombinantes pour la production stable et a haut niveau de proteines biologiquement actives

Country Status (5)

Country Link
US (1) US8158417B2 (fr)
EP (1) EP1960514A1 (fr)
JP (1) JP5061112B2 (fr)
FR (1) FR2892423B1 (fr)
WO (1) WO2007045690A1 (fr)

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ATE270344T1 (de) 1999-11-16 2004-07-15 Atto Tec Gmbh Farbstoffmarkiertes oligonukleotid zum markieren eines nukleinsäuremoleküls
US9867530B2 (en) 2006-08-14 2018-01-16 Volcano Corporation Telescopic side port catheter device with imaging system and method for accessing side branch occlusions
WO2009009802A1 (fr) 2007-07-12 2009-01-15 Volcano Corporation Cathéter oct-ivus pour imagerie luminale simultanée
JP5524835B2 (ja) 2007-07-12 2014-06-18 ヴォルカノ コーポレイション 生体内撮像用カテーテル
US9596993B2 (en) 2007-07-12 2017-03-21 Volcano Corporation Automatic calibration systems and methods of use
WO2010144874A2 (fr) 2009-06-12 2010-12-16 University Of Southern California Produits pharmaceutiques à base de clustérine et procédés de traitement les utilisant
US11141063B2 (en) 2010-12-23 2021-10-12 Philips Image Guided Therapy Corporation Integrated system architectures and methods of use
US11040140B2 (en) 2010-12-31 2021-06-22 Philips Image Guided Therapy Corporation Deep vein thrombosis therapeutic methods
WO2013033592A1 (fr) 2011-08-31 2013-03-07 Volcano Corporation Joint rotatif électro-optique et procédés d'utilisation
US9367965B2 (en) 2012-10-05 2016-06-14 Volcano Corporation Systems and methods for generating images of tissue
US9858668B2 (en) 2012-10-05 2018-01-02 Volcano Corporation Guidewire artifact removal in images
US9324141B2 (en) 2012-10-05 2016-04-26 Volcano Corporation Removal of A-scan streaking artifact
US10568586B2 (en) 2012-10-05 2020-02-25 Volcano Corporation Systems for indicating parameters in an imaging data set and methods of use
US9292918B2 (en) 2012-10-05 2016-03-22 Volcano Corporation Methods and systems for transforming luminal images
US9286673B2 (en) 2012-10-05 2016-03-15 Volcano Corporation Systems for correcting distortions in a medical image and methods of use thereof
US9307926B2 (en) 2012-10-05 2016-04-12 Volcano Corporation Automatic stent detection
EP2904671B1 (fr) 2012-10-05 2022-05-04 David Welford Systèmes et procédés pour amplifier la lumière
US11272845B2 (en) 2012-10-05 2022-03-15 Philips Image Guided Therapy Corporation System and method for instant and automatic border detection
US10070827B2 (en) 2012-10-05 2018-09-11 Volcano Corporation Automatic image playback
US9840734B2 (en) 2012-10-22 2017-12-12 Raindance Technologies, Inc. Methods for analyzing DNA
CA2894403A1 (fr) 2012-12-13 2014-06-19 Volcano Corporation Dispositifs, systemes et procedes de canulation ciblee
EP2934282B1 (fr) 2012-12-20 2020-04-29 Volcano Corporation Localisation d'images intravasculaires
WO2014099899A1 (fr) 2012-12-20 2014-06-26 Jeremy Stigall Cathéters de transition sans heurt
CA2895989A1 (fr) 2012-12-20 2014-07-10 Nathaniel J. Kemp Systeme de tomographie en coherence optique reconfigurable entre differents modes d'imagerie
US10942022B2 (en) 2012-12-20 2021-03-09 Philips Image Guided Therapy Corporation Manual calibration of imaging system
US11406498B2 (en) 2012-12-20 2022-08-09 Philips Image Guided Therapy Corporation Implant delivery system and implants
US10939826B2 (en) 2012-12-20 2021-03-09 Philips Image Guided Therapy Corporation Aspirating and removing biological material
US9486143B2 (en) 2012-12-21 2016-11-08 Volcano Corporation Intravascular forward imaging device
US10166003B2 (en) 2012-12-21 2019-01-01 Volcano Corporation Ultrasound imaging with variable line density
US9612105B2 (en) 2012-12-21 2017-04-04 Volcano Corporation Polarization sensitive optical coherence tomography system
US10191220B2 (en) 2012-12-21 2019-01-29 Volcano Corporation Power-efficient optical circuit
EP2936426B1 (fr) 2012-12-21 2021-10-13 Jason Spencer Système et procédé de traitement graphique de données médicales
US10058284B2 (en) 2012-12-21 2018-08-28 Volcano Corporation Simultaneous imaging, monitoring, and therapy
WO2014100606A1 (fr) 2012-12-21 2014-06-26 Meyer, Douglas Cathéter d'imagerie ultrasonore rotatif muni d'un télescope de corps de cathéter étendu
EP2936626A4 (fr) 2012-12-21 2016-08-17 David Welford Systèmes et procédés permettant de réduire une émission de longueur d'onde de lumière
US10413317B2 (en) 2012-12-21 2019-09-17 Volcano Corporation System and method for catheter steering and operation
CA2895940A1 (fr) 2012-12-21 2014-06-26 Andrew Hancock Systeme et procede pour le traitement multivoie de signaux d'image
US10226597B2 (en) 2013-03-07 2019-03-12 Volcano Corporation Guidewire with centering mechanism
CN113705586A (zh) 2013-03-07 2021-11-26 飞利浦影像引导治疗公司 血管内图像中的多模态分割
CN105228518B (zh) 2013-03-12 2018-10-09 火山公司 用于诊断冠状微脉管疾病的系统和方法
US11154313B2 (en) 2013-03-12 2021-10-26 The Volcano Corporation Vibrating guidewire torquer and methods of use
US11026591B2 (en) 2013-03-13 2021-06-08 Philips Image Guided Therapy Corporation Intravascular pressure sensor calibration
CN105120759B (zh) 2013-03-13 2018-02-23 火山公司 用于从旋转血管内超声设备产生图像的系统和方法
US9301687B2 (en) 2013-03-13 2016-04-05 Volcano Corporation System and method for OCT depth calibration
US10292677B2 (en) 2013-03-14 2019-05-21 Volcano Corporation Endoluminal filter having enhanced echogenic properties
US10219887B2 (en) 2013-03-14 2019-03-05 Volcano Corporation Filters with echogenic characteristics
US20160030151A1 (en) 2013-03-14 2016-02-04 Volcano Corporation Filters with echogenic characteristics
CN105866220A (zh) * 2016-04-18 2016-08-17 苏州新赛美生物科技有限公司 一种高效蛋白转膜缓冲液及其制备方法

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Publication number Priority date Publication date Assignee Title
US7217566B2 (en) * 2003-03-24 2007-05-15 Invitrogen Corporation Attached cell lines
JP4851327B2 (ja) * 2003-09-02 2012-01-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 上皮−間葉移行に関与するサイトカイン
WO2005095448A2 (fr) * 2004-03-23 2005-10-13 Oscient Pharmaceuticals Corporation Methode de synthese et de purification de proteines dkk et proteines dkk ainsi obtenues

Also Published As

Publication number Publication date
EP1960514A1 (fr) 2008-08-27
US20080248526A1 (en) 2008-10-09
US8158417B2 (en) 2012-04-17
WO2007045690A1 (fr) 2007-04-26
FR2892423A1 (fr) 2007-04-27
JP5061112B2 (ja) 2012-10-31
JP2009512431A (ja) 2009-03-26

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Effective date: 20130628