FR2864089B1 - CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM - Google Patents

CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Info

Publication number
FR2864089B1
FR2864089B1 FR0314988A FR0314988A FR2864089B1 FR 2864089 B1 FR2864089 B1 FR 2864089B1 FR 0314988 A FR0314988 A FR 0314988A FR 0314988 A FR0314988 A FR 0314988A FR 2864089 B1 FR2864089 B1 FR 2864089B1
Authority
FR
France
Prior art keywords
chondroid
carboxy
medicine
sulfate
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0314988A
Other languages
French (fr)
Other versions
FR2864089A1 (en
Inventor
Wolfgang Ulmer
Christian Viskov
Philippe Hubert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to FR0314988A priority Critical patent/FR2864089B1/en
Priority to PCT/FR2004/003228 priority patent/WO2005061551A1/en
Priority to US11/016,175 priority patent/US20050187187A1/en
Publication of FR2864089A1 publication Critical patent/FR2864089A1/en
Application granted granted Critical
Publication of FR2864089B1 publication Critical patent/FR2864089B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0314988A 2003-12-19 2003-12-19 CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM Expired - Fee Related FR2864089B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0314988A FR2864089B1 (en) 2003-12-19 2003-12-19 CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM
PCT/FR2004/003228 WO2005061551A1 (en) 2003-12-19 2004-12-15 Carboxy-reduced derivatives of chondroitin sulphate, method of preparing said derivatives, application thereof as a medicament and pharmaceutical compositions containing same
US11/016,175 US20050187187A1 (en) 2003-12-19 2004-12-17 Carboxyl-reduced derivatives of chondroitin sulfate, preparation thereof, use thereof as a medicinal product and the pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0314988A FR2864089B1 (en) 2003-12-19 2003-12-19 CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Publications (2)

Publication Number Publication Date
FR2864089A1 FR2864089A1 (en) 2005-06-24
FR2864089B1 true FR2864089B1 (en) 2006-02-03

Family

ID=34630339

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0314988A Expired - Fee Related FR2864089B1 (en) 2003-12-19 2003-12-19 CHONDROID SULFATE CARBOXY-REDUCED DERIVATIVES, THEIR PREPARATION, THEIR APPLICATION AS MEDICINE AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THEM

Country Status (2)

Country Link
FR (1) FR2864089B1 (en)
WO (1) WO2005061551A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114057908A (en) * 2020-08-08 2022-02-18 烟台东诚药业集团股份有限公司 Preparation method of low-molecular sodium chondroitin sulfate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262403A (en) * 1986-03-10 1993-11-16 Board Of Regents, The University Of Texas System Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II
SE453394B (en) * 1986-07-07 1988-02-01 Pharmacia Ab PROCEDURE FOR PREPARING SULPHATATED POLYSACcharides BY USING A REDUCING AGENT FOR THE SULPHATING REACTION
WO1992013541A1 (en) * 1991-01-30 1992-08-20 Hoechst Aktiengesellschaft Use of substituted polysaccharides for the treatment of degenerative articular ailments
AU7205894A (en) * 1993-06-08 1995-01-03 Neogenix, Inc. Purified natural and synthetic compounds for the treatment of osteoarthritis
JP2000080102A (en) * 1998-09-04 2000-03-21 Shin Nippon Yakugyou Kk O-persulfated glycosaminoglycan and anticoagulant containing same as effective ingredient

Also Published As

Publication number Publication date
FR2864089A1 (en) 2005-06-24
WO2005061551A1 (en) 2005-07-07

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20081020