FR2844521B1 - MEASUREMENT OF THE PRODUCTION OF CYTOKINES AS A MARKER FOR ACTIVATION OF EFFECTOR CELLS - Google Patents
MEASUREMENT OF THE PRODUCTION OF CYTOKINES AS A MARKER FOR ACTIVATION OF EFFECTOR CELLSInfo
- Publication number
- FR2844521B1 FR2844521B1 FR0211416A FR0211416A FR2844521B1 FR 2844521 B1 FR2844521 B1 FR 2844521B1 FR 0211416 A FR0211416 A FR 0211416A FR 0211416 A FR0211416 A FR 0211416A FR 2844521 B1 FR2844521 B1 FR 2844521B1
- Authority
- FR
- France
- Prior art keywords
- cytokines
- marker
- activation
- measurement
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (35)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0211416A FR2844521B1 (en) | 2002-09-13 | 2002-09-13 | MEASUREMENT OF THE PRODUCTION OF CYTOKINES AS A MARKER FOR ACTIVATION OF EFFECTOR CELLS |
FR0307066A FR2844455B1 (en) | 2002-09-13 | 2003-06-12 | TREATMENT OF PATHOLOGIES EXCLUDING IMMUNE RESPONSE BY OPTIMIZED ANTIBODIES |
FR0307067A FR2844513B1 (en) | 2002-09-13 | 2003-06-12 | ANTIBODIES FOR ADCC AND INDUCING PRODUCTION OF CYTOKINS. |
AT03773779T ATE486094T1 (en) | 2002-09-13 | 2003-09-15 | ADCC-MEDIATING ANTIBODIES AGAINST HLA-DR THAT INDUCE THE PRODUCTION OF CYTOKINES |
AU2003282160A AU2003282160A1 (en) | 2002-09-13 | 2003-09-15 | Antibody for adcc and inducing cytokine production |
DE60334700T DE60334700D1 (en) | 2002-09-13 | 2003-09-15 | ADCC-RELATED ANTIBODIES TO HLA-DR INDUCING THE PRODUCTION OF CYTOKINS |
CA2498383A CA2498383C (en) | 2002-09-13 | 2003-09-15 | Treatment of pathologies which escape the immune response, using optimised antibodies |
EP15182965.2A EP3001198A1 (en) | 2002-09-13 | 2003-09-15 | Treatment of conditions escaping the immune response by optimised antibodies |
US10/527,664 US20060127392A1 (en) | 2002-09-13 | 2003-09-15 | Antibody for adcc and inducing cytokine production |
CA002498787A CA2498787A1 (en) | 2002-09-13 | 2003-09-15 | Antibody for adcc and inducing cytokine production |
PCT/FR2003/002715 WO2004024768A2 (en) | 2002-09-13 | 2003-09-15 | Cytokine production-inducing antibody |
US10/527,665 US7595165B2 (en) | 2002-09-13 | 2003-09-15 | Method of measuring activation of effector cells |
JP2004535611A JP4368800B2 (en) | 2002-09-13 | 2003-09-15 | Cytokine production-inducing antibody |
AU2003283469A AU2003283469C1 (en) | 2002-09-13 | 2003-09-15 | Treatment of pathologies which escape the immune response, using optimised antibodies |
JP2004539110A JP2006504700A (en) | 2002-09-13 | 2003-09-15 | Treatment of pathological conditions that escape immune responses using optimized antibodies |
CA2498315A CA2498315C (en) | 2002-09-13 | 2003-09-15 | Cytokine production-inducing antibody |
DK03773780.6T DK1537419T3 (en) | 2002-09-13 | 2003-09-15 | Test for CD16-mediated ADCC efficacy of monoclonal and polyclonal antibodies |
PCT/FR2003/002714 WO2004028564A2 (en) | 2002-09-13 | 2003-09-15 | Treatment of pathologies which escape the immune response, using optimised antibodies |
EP03773779A EP1537147B9 (en) | 2002-09-13 | 2003-09-15 | Antibody anti hla-dr with an increased adcc and inducing cytokine production |
AU2003282161A AU2003282161B2 (en) | 2002-09-13 | 2003-09-15 | Cytokine production-inducing antibody |
PCT/FR2003/002713 WO2004029092A2 (en) | 2002-09-13 | 2003-09-15 | Antibody for adcc and inducing cytokine production |
JP2004539109A JP2006516951A (en) | 2002-09-13 | 2003-09-15 | Antibodies for induction of ADCC and cytokine production |
EP03773780A EP1537419B1 (en) | 2002-09-13 | 2003-09-15 | Test for CD16-mediated ADCC efficacy of monoclonal or polyclonal antibodies |
US10/527,666 US20050271652A1 (en) | 2002-09-13 | 2003-09-15 | Treatment of pathologies which escape the immune response, using optimised antibodies |
EP09152731A EP2092939A3 (en) | 2002-09-13 | 2003-09-15 | Therapeutical use of antibody inducing the production of cytokines |
AT03773780T ATE511654T1 (en) | 2002-09-13 | 2003-09-15 | TEST FOR CD16-MEDIATED ADCC EFFECTIVENESS OF MONOCLONAL OR POCLONAL ANTIBODIES |
EP03775438A EP1545614A2 (en) | 2002-09-13 | 2003-09-15 | Treatment of pathologies which escape the immune response, using optimised antibodies |
IL167385A IL167385A (en) | 2002-09-13 | 2005-03-10 | Method for selecting a monoclonal antibody for increased antibody-dependent cellular cytotoxicity activity |
IL167381A IL167381A (en) | 2002-09-13 | 2005-03-10 | Use of an optimized monoclonal antibody for preparing a medicinal product for the treatment of pathologies which escape the immune response |
US12/234,609 US20090081216A1 (en) | 2002-09-13 | 2008-09-19 | Treatment of pathologies which escape the immune response, using optimized antibodies |
JP2009190989A JP5951923B2 (en) | 2002-09-13 | 2009-08-20 | Treatment of pathological conditions that escape immune responses using optimized antibodies |
US12/585,900 US20100323368A1 (en) | 2002-09-13 | 2009-09-28 | Cytokine production-inducing antibody |
US12/576,202 US20100145026A1 (en) | 2002-09-13 | 2009-10-08 | Antibody for ADCC And Inducing Cytokine Production |
IL230101A IL230101A (en) | 2002-09-13 | 2013-12-23 | Use of optimized antibodies for preparing medicaments for treatment of pathologies which escape the immune response |
JP2013272030A JP6238743B2 (en) | 2002-09-13 | 2013-12-27 | Treatment of pathological conditions that escape immune responses using optimized antibodies |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0211416A FR2844521B1 (en) | 2002-09-13 | 2002-09-13 | MEASUREMENT OF THE PRODUCTION OF CYTOKINES AS A MARKER FOR ACTIVATION OF EFFECTOR CELLS |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2844521A1 FR2844521A1 (en) | 2004-03-19 |
FR2844521B1 true FR2844521B1 (en) | 2004-12-24 |
Family
ID=31897391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0211416A Expired - Lifetime FR2844521B1 (en) | 2002-09-13 | 2002-09-13 | MEASUREMENT OF THE PRODUCTION OF CYTOKINES AS A MARKER FOR ACTIVATION OF EFFECTOR CELLS |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2844521B1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2894983B1 (en) * | 2005-12-16 | 2012-08-17 | Lab Francais Du Fractionnement | ANTIBODY CHARACTERIZATION TEST. |
EP1933137A1 (en) * | 2006-12-15 | 2008-06-18 | Glycode | Method of investigating the response to a treatment using a monoclonal antibody |
EP2062047B1 (en) * | 2006-09-13 | 2011-03-09 | Glycode | Method for investigating the response to a treatment with a monoclonal antibody |
FR2980271B1 (en) | 2011-09-16 | 2013-10-11 | Cisbio Bioassays | METHOD FOR DETERMINING GLYCOSYLATION OF ANTIBODY |
FR2988174B1 (en) | 2012-03-19 | 2014-04-25 | Cisbio Bioassays | METHOD FOR DETERMINING THE CAPACITY OF ANTIBODY TO MAINTAIN CELLS CLOSE TO EACH OTHER |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2807767B1 (en) * | 2000-04-12 | 2005-01-14 | Lab Francais Du Fractionnement | MONOCLONAL ANTIBODIES ANTI-D |
AU2001267922A1 (en) * | 2000-07-04 | 2002-01-14 | Chugai Seiyaku Kabushiki Kaisha | Method of assaying the function of fc fragment of antibody |
-
2002
- 2002-09-13 FR FR0211416A patent/FR2844521B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FR2844521A1 (en) | 2004-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property | ||
TP | Transmission of property |
Owner name: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES , FR Effective date: 20130903 |
|
PLFP | Fee payment |
Year of fee payment: 15 |
|
PLFP | Fee payment |
Year of fee payment: 16 |