FR2834636B1 - Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees - Google Patents

Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees

Info

Publication number
FR2834636B1
FR2834636B1 FR0200427A FR0200427A FR2834636B1 FR 2834636 B1 FR2834636 B1 FR 2834636B1 FR 0200427 A FR0200427 A FR 0200427A FR 0200427 A FR0200427 A FR 0200427A FR 2834636 B1 FR2834636 B1 FR 2834636B1
Authority
FR
France
Prior art keywords
inhalation
manufacture
porous particles
hollow micro
micro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0200427A
Other languages
English (en)
Other versions
FR2834636A1 (fr
Inventor
El Hassane Larhrib
Okpala Joseph Chukwuemeka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR0200427A priority Critical patent/FR2834636B1/fr
Priority to PCT/FR2003/000102 priority patent/WO2003059324A1/fr
Priority to AU2003214315A priority patent/AU2003214315A1/en
Priority to US10/501,485 priority patent/US20050214226A1/en
Priority to EP03709880A priority patent/EP1465603A1/fr
Publication of FR2834636A1 publication Critical patent/FR2834636A1/fr
Application granted granted Critical
Publication of FR2834636B1 publication Critical patent/FR2834636B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
FR0200427A 2002-01-15 2002-01-15 Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees Expired - Fee Related FR2834636B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0200427A FR2834636B1 (fr) 2002-01-15 2002-01-15 Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees
PCT/FR2003/000102 WO2003059324A1 (fr) 2002-01-15 2003-01-14 Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees
AU2003214315A AU2003214315A1 (en) 2002-01-15 2003-01-14 Method of producing hollow, microporous particles which are intended, in particular, to be inhaled
US10/501,485 US20050214226A1 (en) 2002-01-15 2003-01-14 Method of producing hollow, microporous particles which are intended, in particular to be inhaled
EP03709880A EP1465603A1 (fr) 2002-01-15 2003-01-14 Procede de fabrication de particules microporeuses creuses notamment destinees a etre inhalees

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0200427A FR2834636B1 (fr) 2002-01-15 2002-01-15 Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees

Publications (2)

Publication Number Publication Date
FR2834636A1 FR2834636A1 (fr) 2003-07-18
FR2834636B1 true FR2834636B1 (fr) 2006-02-24

Family

ID=8871289

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0200427A Expired - Fee Related FR2834636B1 (fr) 2002-01-15 2002-01-15 Procede de fabrication de particules micro-poreuses creuses, notamment destinees a etre inhalees

Country Status (5)

Country Link
US (1) US20050214226A1 (fr)
EP (1) EP1465603A1 (fr)
AU (1) AU2003214315A1 (fr)
FR (1) FR2834636B1 (fr)
WO (1) WO2003059324A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0228826D0 (en) * 2002-12-11 2003-01-15 Okpala Joseph Hair technology in creating particles with improved delivery capabilities
US6931888B2 (en) * 2003-02-07 2005-08-23 Ferro Corporation Lyophilization method and apparatus for producing particles
GB0709115D0 (en) * 2007-05-11 2007-06-20 Katholieke Universltelt Leuven Membrane comprising hollow particles
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2030551C (fr) * 1989-05-01 1998-08-25 Wayne Gombotz Procede de production de particules formees de molecules actives biologiquement
US5019400A (en) * 1989-05-01 1991-05-28 Enzytech, Inc. Very low temperature casting of controlled release microspheres
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
ES2261195T3 (es) * 1999-04-05 2006-11-16 Mannkind Corporation Metodo de formacion de particulas finas.

Also Published As

Publication number Publication date
AU2003214315A1 (en) 2003-07-30
WO2003059324A1 (fr) 2003-07-24
US20050214226A1 (en) 2005-09-29
FR2834636A1 (fr) 2003-07-18
EP1465603A1 (fr) 2004-10-13

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20110930