FR2828284B1 - Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support - Google Patents

Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support

Info

Publication number
FR2828284B1
FR2828284B1 FR0110302A FR0110302A FR2828284B1 FR 2828284 B1 FR2828284 B1 FR 2828284B1 FR 0110302 A FR0110302 A FR 0110302A FR 0110302 A FR0110302 A FR 0110302A FR 2828284 B1 FR2828284 B1 FR 2828284B1
Authority
FR
France
Prior art keywords
complexation
hybridization
detection
amplified signal
support
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0110302A
Other languages
English (en)
Other versions
FR2828284A1 (fr
Inventor
Francis Garnier
Bernard Mandrand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Original Assignee
Biomerieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA filed Critical Biomerieux SA
Priority to FR0110302A priority Critical patent/FR2828284B1/fr
Priority to EP02779605A priority patent/EP1412726A1/fr
Priority to US10/485,328 priority patent/US20040234991A1/en
Priority to PCT/FR2002/002781 priority patent/WO2003012410A1/fr
Priority to JP2003517554A priority patent/JP2004537722A/ja
Publication of FR2828284A1 publication Critical patent/FR2828284A1/fr
Application granted granted Critical
Publication of FR2828284B1 publication Critical patent/FR2828284B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00529—DNA chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00952—Sensing operations
    • B01J2219/00968—Type of sensors
    • B01J2219/0097—Optical sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
FR0110302A 2001-08-01 2001-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support Expired - Fee Related FR2828284B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0110302A FR2828284B1 (fr) 2001-08-01 2001-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support
EP02779605A EP1412726A1 (fr) 2001-08-01 2002-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support
US10/485,328 US20040234991A1 (en) 2001-08-01 2002-08-01 Method for detecting at a solid support of complexing or hybridization between at least two basic molecules based on an amplified signal at the support
PCT/FR2002/002781 WO2003012410A1 (fr) 2001-08-01 2002-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support
JP2003517554A JP2004537722A (ja) 2001-08-01 2002-08-01 少なくとも２個の基本的分子間の複合体形成又はハイブリダイゼーションを固体支持体上で該支持体における増幅信号に基づいて検出する検出方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0110302A FR2828284B1 (fr) 2001-08-01 2001-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support

Publications (2)

Publication Number Publication Date
FR2828284A1 FR2828284A1 (fr) 2003-02-07
FR2828284B1 true FR2828284B1 (fr) 2003-10-31

Family

ID=8866170

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0110302A Expired - Fee Related FR2828284B1 (fr) 2001-08-01 2001-08-01 Procede de detection au niveau d'un support solide d'une complexation ou d'une hybridation entre au moins deux molecules base sur un signal amplifie au niveau du support

Country Status (5)

Country Link
US (1) US20040234991A1 (fr)
EP (1) EP1412726A1 (fr)
JP (1) JP2004537722A (fr)
FR (1) FR2828284B1 (fr)
WO (1) WO2003012410A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10311315A1 (de) 2003-03-14 2004-09-30 Apibio Sas Verfahren und Vorrichtung zur Detektion von Biomolekülen
JP4920553B2 (ja) * 2006-11-08 2012-04-18 富士フイルム株式会社 イムノクロマトグラフキット
KR100819006B1 (ko) * 2007-02-13 2008-04-03 삼성전자주식회사 마이크로 어레이용 마스크 세트, 이의 제조 방법, 및마스크 세트를 이용한 마이크로 어레이의 제조 방법
ITMI20110739A1 (it) * 2011-05-03 2011-08-02 Copan Information Technologies S R L Apparecchiatura e procedimento per il trattamento di campioni di materiale biologico, microbiologico e/o chimico
CN111665238A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种化学发光微阵列芯片的应用
CN111665235A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种化学发光微阵列芯片及其应用
CN111665236A (zh) * 2019-03-08 2020-09-15 上海索昕生物科技有限公司 一种发光微阵列芯片的制备方法及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2392003A (en) * 1942-09-26 1946-01-01 O W Wortman Method and apparatus for detecting and measuring radiant energy such as light
US4197361A (en) * 1977-08-23 1980-04-08 Warner-Lambert Fluorescent immunoassay sandwich technique for HBs Ag
SU1275226A1 (ru) * 1985-04-25 1986-12-07 Институт физики твердого тела АН СССР Устройство дл регистрации светового излучени
US4739044A (en) * 1985-06-13 1988-04-19 Amgen Method for derivitization of polynucleotides
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US5294369A (en) * 1990-12-05 1994-03-15 Akzo N.V. Ligand gold bonding
US6099803A (en) * 1994-07-07 2000-08-08 Nanogen, Inc. Advanced active electronic devices for molecular biological analysis and diagnostics
WO1995030774A1 (fr) * 1994-05-05 1995-11-16 Beckman Instruments, Inc. Groupements repetes d'oligonucleotides
US6168948B1 (en) * 1995-06-29 2001-01-02 Affymetrix, Inc. Miniaturized genetic analysis systems and methods
DE19615771A1 (de) * 1996-04-20 1997-10-23 Hymmen Theodor Gmbh Doppelbandpresse zum Herstellen und/oder zum Beschichten von bahn- oder plattenförmigen Werkstücken aller Art
US6043342A (en) * 1997-11-10 2000-03-28 Beth Israel Deaconess Medical Center PDZK1 protein containing PDZ interaction domains
AU2740000A (en) * 1999-01-25 2000-08-07 Lockheed Martin Energy Research Corporation Multifunctional and multispectral biosensor devices and methods of use
US6136541A (en) * 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US20030096321A1 (en) * 1999-05-19 2003-05-22 Jose Remacle Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips
US20010031469A1 (en) * 2000-01-03 2001-10-18 Stefano Volinia Methods for the detection of modified peptides, proteins and other molecules
US20020160400A1 (en) * 2001-02-14 2002-10-31 Lakowicz Joseph R. Radiative decay engineering

Also Published As

Publication number Publication date
WO2003012410A1 (fr) 2003-02-13
US20040234991A1 (en) 2004-11-25
FR2828284A1 (fr) 2003-02-07
EP1412726A1 (fr) 2004-04-28
JP2004537722A (ja) 2004-12-16

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Effective date: 20110502