FR2814367B1 - NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA - Google Patents

NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA

Info

Publication number
FR2814367B1
FR2814367B1 FR0012164A FR0012164A FR2814367B1 FR 2814367 B1 FR2814367 B1 FR 2814367B1 FR 0012164 A FR0012164 A FR 0012164A FR 0012164 A FR0012164 A FR 0012164A FR 2814367 B1 FR2814367 B1 FR 2814367B1
Authority
FR
France
Prior art keywords
hyperalgia
pain
treatment
receptor ligands
npff receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0012164A
Other languages
French (fr)
Other versions
FR2814367A1 (en
Inventor
Jean Jacques Bourguignon
Jean Paul Macher
Martine Schmitt
Guy Simonnet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to FR0012164A priority Critical patent/FR2814367B1/en
Priority to PCT/FR2001/002973 priority patent/WO2002024192A1/en
Priority to AU2001291994A priority patent/AU2001291994A1/en
Publication of FR2814367A1 publication Critical patent/FR2814367A1/en
Application granted granted Critical
Publication of FR2814367B1 publication Critical patent/FR2814367B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
FR0012164A 2000-09-25 2000-09-25 NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA Expired - Fee Related FR2814367B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR0012164A FR2814367B1 (en) 2000-09-25 2000-09-25 NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA
PCT/FR2001/002973 WO2002024192A1 (en) 2000-09-25 2001-09-25 Dipeptide ligands of the npff receptor for treating pain and hyperalgesia
AU2001291994A AU2001291994A1 (en) 2000-09-25 2001-09-25 Dipeptide ligands of the npff receptor for treating pain and hyperalgesia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0012164A FR2814367B1 (en) 2000-09-25 2000-09-25 NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA

Publications (2)

Publication Number Publication Date
FR2814367A1 FR2814367A1 (en) 2002-03-29
FR2814367B1 true FR2814367B1 (en) 2008-12-26

Family

ID=8854636

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0012164A Expired - Fee Related FR2814367B1 (en) 2000-09-25 2000-09-25 NPFF RECEPTOR LIGANDS FOR THE TREATMENT OF PAIN AND HYPERALGIA

Country Status (3)

Country Link
AU (1) AU2001291994A1 (en)
FR (1) FR2814367B1 (en)
WO (1) WO2002024192A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276249B2 (en) 2002-05-24 2007-10-02 Elan Pharma International, Ltd. Nanoparticulate fibrate formulations
JPWO2004080965A1 (en) * 2003-03-14 2006-06-08 協和醗酵工業株式会社 Neuropeptide FF receptor antagonist
CL2004000553A1 (en) 2003-03-20 2005-02-04 Actelion Pharmaceuticals Ltd USE OF GUANIDINE DERIVATIVE COMPOUNDS AS ANTAGONISTS OF THE FF NEUROPEPTIDE RECEIVER; COMPOUNDS DERIVED FROM GUANIDINA; PREPARATION PROCEDURES; AND PHARMACEUTICAL COMPOSITION THAT UNDERSTANDS THEM.
FI20031454A0 (en) 2003-10-06 2003-10-06 Juvantia Pharma Ltd Oy Selective somatostatin receptor 1 and / or 4 agonists and antagonists
EP2669276A1 (en) 2012-05-31 2013-12-04 Université de Strasbourg Ornithine- and lysine-derivatives for the treatment of pain
KR102375543B1 (en) * 2017-07-21 2022-03-16 스촨 하이스코 파마수티컬 씨오., 엘티디 Peptide amide compounds and methods for their preparation and use in medicine
AU2019213484A1 (en) 2018-02-05 2020-07-02 Centre National De La Recherche Scientifique Compounds and compositions for the treatment of pain
CA3144527A1 (en) 2019-08-06 2021-02-11 Domain Therapeutics 5-heteroaryl-pyridin-2-amine confounds as neuropeptide ff receptor antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4326465A1 (en) * 1993-01-20 1995-02-09 Thomae Gmbh Dr K Amino acid derivatives, pharmaceutical compositions containing these compounds and process for their preparation
GB9500601D0 (en) * 1995-01-12 1995-03-01 Wellcome Found Modified peptides
DE19544686A1 (en) * 1995-11-30 1997-06-05 Thomae Gmbh Dr K Amino acid derivatives, medicaments containing these compounds and processes for their preparation
US6262246B1 (en) * 1998-09-25 2001-07-17 Synaptic Pharmaceutical Corporation DNA encoding mammalian neuropeptides FF (NPFF) receptors and uses thereof

Also Published As

Publication number Publication date
AU2001291994A1 (en) 2002-04-02
WO2002024192A1 (en) 2002-03-28
FR2814367A1 (en) 2002-03-29

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Legal Events

Date Code Title Description
TQ Partial transmission of property
TQ Partial transmission of property
ST Notification of lapse

Effective date: 20120531