FR2791142B1 - USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs - Google Patents

USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs

Info

Publication number
FR2791142B1
FR2791142B1 FR9903304A FR9903304A FR2791142B1 FR 2791142 B1 FR2791142 B1 FR 2791142B1 FR 9903304 A FR9903304 A FR 9903304A FR 9903304 A FR9903304 A FR 9903304A FR 2791142 B1 FR2791142 B1 FR 2791142B1
Authority
FR
France
Prior art keywords
brefeldine
cpas
presentation
increase
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9903304A
Other languages
French (fr)
Other versions
FR2791142A1 (en
Inventor
Emmanuel Drouet
Cecile Verniol
Christian Drouet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Joseph Fourier Grenoble 1
Original Assignee
Universite Joseph Fourier Grenoble 1
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Joseph Fourier Grenoble 1 filed Critical Universite Joseph Fourier Grenoble 1
Priority to FR9903304A priority Critical patent/FR2791142B1/en
Priority to AU32988/00A priority patent/AU3298800A/en
Priority to EP00910959A priority patent/EP1163516A1/en
Priority to PCT/FR2000/000636 priority patent/WO2000055622A1/en
Publication of FR2791142A1 publication Critical patent/FR2791142A1/en
Application granted granted Critical
Publication of FR2791142B1 publication Critical patent/FR2791142B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
FR9903304A 1999-03-17 1999-03-17 USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs Expired - Fee Related FR2791142B1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR9903304A FR2791142B1 (en) 1999-03-17 1999-03-17 USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs
AU32988/00A AU3298800A (en) 1999-03-17 2000-03-16 Effect of brefeldin a on antigen-presenting cells
EP00910959A EP1163516A1 (en) 1999-03-17 2000-03-16 Effect of brefeldin a on antigen-presenting cells
PCT/FR2000/000636 WO2000055622A1 (en) 1999-03-17 2000-03-16 Effect of brefeldin a on antigen-presenting cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9903304A FR2791142B1 (en) 1999-03-17 1999-03-17 USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs

Publications (2)

Publication Number Publication Date
FR2791142A1 FR2791142A1 (en) 2000-09-22
FR2791142B1 true FR2791142B1 (en) 2001-06-22

Family

ID=9543309

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9903304A Expired - Fee Related FR2791142B1 (en) 1999-03-17 1999-03-17 USE OF BREFELDINE A TO INCREASE THE EFFECT OF PRESENTATION OF EXOGENOUS ANTIGENS BY CPAs

Country Status (4)

Country Link
EP (1) EP1163516A1 (en)
AU (1) AU3298800A (en)
FR (1) FR2791142B1 (en)
WO (1) WO2000055622A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2101177A1 (en) * 2008-03-10 2009-09-16 Universite Joseph Fourier Use of synthetic peptide derived from zebra protein for the in vitro diagnosis of the epstein-barr virus (EBV) reactivation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474769A (en) * 1991-03-08 1995-12-12 Sterling Winthrop Inc. Treatment of microbial infection by monocyte stimulation with interleukin-7
US5112607A (en) * 1991-06-05 1992-05-12 The United States Of America As Represented By The Secretary Of The Army Potentiation of immunotoxin action by Brefeldin A
US5254342A (en) * 1991-09-30 1993-10-19 University Of Southern California Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
WO1994006470A1 (en) * 1992-09-15 1994-03-31 Johnson & Johnson Immunoreactive peptides from epstein-barr virus
WO1996020723A1 (en) * 1994-12-30 1996-07-11 Brigham & Women's Hospital Controlling traf-mediated signals
FR2728904B1 (en) * 1995-01-04 1997-03-14 Pasteur Institut PEPTIDE REAGENT FOR DETECTING PRIMARY INFECTION WITH EPSTEIN-BARR VIRUS BY SEARCHING CORRESPONDING ANTIBODIES, AND METHOD OF USING THE SAME

Also Published As

Publication number Publication date
EP1163516A1 (en) 2001-12-19
AU3298800A (en) 2000-10-04
WO2000055622A1 (en) 2000-09-21
FR2791142A1 (en) 2000-09-22

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Legal Events

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ST Notification of lapse