FR2781224B1 - 1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP - Google Patents

1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP

Info

Publication number
FR2781224B1
FR2781224B1 FR9809167A FR9809167A FR2781224B1 FR 2781224 B1 FR2781224 B1 FR 2781224B1 FR 9809167 A FR9809167 A FR 9809167A FR 9809167 A FR9809167 A FR 9809167A FR 2781224 B1 FR2781224 B1 FR 2781224B1
Authority
FR
France
Prior art keywords
dihydropyridines
sulfonamide group
sulfonamide
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9809167A
Other languages
French (fr)
Other versions
FR2781224A1 (en
Inventor
Gerard Duret
Gerard Glauert
Andre Pessonnier
Marguerite Henry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Priority to FR9809167A priority Critical patent/FR2781224B1/en
Priority to AU47897/99A priority patent/AU4789799A/en
Priority to PCT/FR1999/001746 priority patent/WO2000003987A1/en
Publication of FR2781224A1 publication Critical patent/FR2781224A1/en
Application granted granted Critical
Publication of FR2781224B1 publication Critical patent/FR2781224B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9809167A 1998-07-17 1998-07-17 1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP Expired - Fee Related FR2781224B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9809167A FR2781224B1 (en) 1998-07-17 1998-07-17 1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP
AU47897/99A AU4789799A (en) 1998-07-17 1999-07-16 1,4-dihydropyridines as calcium blockers
PCT/FR1999/001746 WO2000003987A1 (en) 1998-07-17 1999-07-16 1,4-dihydropyridines as calcium blockers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9809167A FR2781224B1 (en) 1998-07-17 1998-07-17 1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP

Publications (2)

Publication Number Publication Date
FR2781224A1 FR2781224A1 (en) 2000-01-21
FR2781224B1 true FR2781224B1 (en) 2000-10-13

Family

ID=9528733

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9809167A Expired - Fee Related FR2781224B1 (en) 1998-07-17 1998-07-17 1,4-DIHYDROPYRIDINES WITH SULFONAMIDE GROUP

Country Status (3)

Country Link
AU (1) AU4789799A (en)
FR (1) FR2781224B1 (en)
WO (1) WO2000003987A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671349B1 (en) * 1991-01-09 1993-04-23 Lafon Labor NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITION CONTAINING THEM.
AU4586093A (en) * 1992-07-28 1994-02-14 Daicel Chemical Industries Ltd. Antihypertensive 1,4-dihydropyridine derivatives and process for their preparation

Also Published As

Publication number Publication date
FR2781224A1 (en) 2000-01-21
AU4789799A (en) 2000-02-07
WO2000003987A1 (en) 2000-01-27

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Legal Events

Date Code Title Description
ST Notification of lapse