FR2780967B1 - PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES - Google Patents

PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES

Info

Publication number
FR2780967B1
FR2780967B1 FR9808981A FR9808981A FR2780967B1 FR 2780967 B1 FR2780967 B1 FR 2780967B1 FR 9808981 A FR9808981 A FR 9808981A FR 9808981 A FR9808981 A FR 9808981A FR 2780967 B1 FR2780967 B1 FR 2780967B1
Authority
FR
France
Prior art keywords
dihydrobenzofurane
disubstitued
derivatives
preparation
disubstitued derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9808981A
Other languages
French (fr)
Other versions
FR2780967A1 (en
Inventor
Patrice Mayer
Thierry Imbert
Karine Couture
Veronique Gouverneur
Charles Mioskowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR9808981A priority Critical patent/FR2780967B1/en
Priority to AU47885/99A priority patent/AU4788599A/en
Priority to PCT/FR1999/001702 priority patent/WO2000002836A1/en
Publication of FR2780967A1 publication Critical patent/FR2780967A1/en
Application granted granted Critical
Publication of FR2780967B1 publication Critical patent/FR2780967B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
FR9808981A 1998-07-13 1998-07-13 PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES Expired - Fee Related FR2780967B1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9808981A FR2780967B1 (en) 1998-07-13 1998-07-13 PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES
AU47885/99A AU4788599A (en) 1998-07-13 1999-07-12 Method for preparing 2-disubstituted 2,3-dihydrobenzofuran derivatives
PCT/FR1999/001702 WO2000002836A1 (en) 1998-07-13 1999-07-12 Method for preparing 2-disubstituted 2,3-dihydrobenzofuran derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9808981A FR2780967B1 (en) 1998-07-13 1998-07-13 PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES

Publications (2)

Publication Number Publication Date
FR2780967A1 FR2780967A1 (en) 2000-01-14
FR2780967B1 true FR2780967B1 (en) 2000-09-29

Family

ID=9528598

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9808981A Expired - Fee Related FR2780967B1 (en) 1998-07-13 1998-07-13 PROCESS FOR THE PREPARATION OF 2,3-DIHYDROBENZOFURANE -2,2-DISUBSTITUED DERIVATIVES

Country Status (3)

Country Link
AU (1) AU4788599A (en)
FR (1) FR2780967B1 (en)
WO (1) WO2000002836A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117645D0 (en) * 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
US7862169B2 (en) 2006-09-29 2011-01-04 Johnson & Johnson Vision Care, Inc. Contact lenses and methods for their design

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2315925A1 (en) * 1975-07-04 1977-01-28 Nippon Chemiphar Co NEW 5-BENZYL-2-OXAZOLIDONE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
FR2733983B1 (en) * 1995-05-10 1997-08-01 Pf Medicament PROCESS FOR THE PREPARATION OF AN OPTICALLY PURE BENZOFURANE CARBOXYLIC ACID DERIVATIVE AND THE USE THEREOF FOR THE PREPARATION OF EFAROXAN

Also Published As

Publication number Publication date
WO2000002836A1 (en) 2000-01-20
FR2780967A1 (en) 2000-01-14
AU4788599A (en) 2000-02-01

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Legal Events

Date Code Title Description
ST Notification of lapse