FR2774989B1 - NEW CYTOTOXICS DERIVED FROM OESTRADIOL - Google Patents

NEW CYTOTOXICS DERIVED FROM OESTRADIOL

Info

Publication number
FR2774989B1
FR2774989B1 FR9801959A FR9801959A FR2774989B1 FR 2774989 B1 FR2774989 B1 FR 2774989B1 FR 9801959 A FR9801959 A FR 9801959A FR 9801959 A FR9801959 A FR 9801959A FR 2774989 B1 FR2774989 B1 FR 2774989B1
Authority
FR
France
Prior art keywords
cytotoxics
oestradiol
derived
new
new cytotoxics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9801959A
Other languages
French (fr)
Other versions
FR2774989A1 (en
Inventor
Patrick Jouin
Joel Poncet
Magali Busquet
Ghanem Atassi
Alain Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADIR SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Priority to FR9801959A priority Critical patent/FR2774989B1/en
Publication of FR2774989A1 publication Critical patent/FR2774989A1/en
Application granted granted Critical
Publication of FR2774989B1 publication Critical patent/FR2774989B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9801959A 1998-02-18 1998-02-18 NEW CYTOTOXICS DERIVED FROM OESTRADIOL Expired - Fee Related FR2774989B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9801959A FR2774989B1 (en) 1998-02-18 1998-02-18 NEW CYTOTOXICS DERIVED FROM OESTRADIOL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9801959A FR2774989B1 (en) 1998-02-18 1998-02-18 NEW CYTOTOXICS DERIVED FROM OESTRADIOL

Publications (2)

Publication Number Publication Date
FR2774989A1 FR2774989A1 (en) 1999-08-20
FR2774989B1 true FR2774989B1 (en) 2000-03-17

Family

ID=9523097

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9801959A Expired - Fee Related FR2774989B1 (en) 1998-02-18 1998-02-18 NEW CYTOTOXICS DERIVED FROM OESTRADIOL

Country Status (1)

Country Link
FR (1) FR2774989B1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105636592A (en) 2013-07-11 2016-06-01 伊万斯彻有限公司 Pro-drug forming compounds
MX2020003470A (en) 2017-10-19 2020-10-01 Evestra Inc Longer-acting progestin prodrug contraceptives.
EP4051691A4 (en) * 2019-10-28 2023-11-08 Ariel Scientific Innovations Ltd. Dolastatin 10 analog

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5663149A (en) * 1994-12-13 1997-09-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide heterocyclic and halophenyl amides
US5807984A (en) * 1995-11-09 1998-09-15 Basf Aktienegesellschaft Oligopeptides, the preparation and use thereof

Also Published As

Publication number Publication date
FR2774989A1 (en) 1999-08-20

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse