FR2751326B1 - PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE - Google Patents

PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE

Info

Publication number
FR2751326B1
FR2751326B1 FR9608885A FR9608885A FR2751326B1 FR 2751326 B1 FR2751326 B1 FR 2751326B1 FR 9608885 A FR9608885 A FR 9608885A FR 9608885 A FR9608885 A FR 9608885A FR 2751326 B1 FR2751326 B1 FR 2751326B1
Authority
FR
France
Prior art keywords
trifluoromethylbenzene
acetamido
amino
formula
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9608885A
Other languages
French (fr)
Other versions
FR2751326A1 (en
Inventor
Michel Dury
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhodia Chimie SAS
Original Assignee
Rhone Poulenc Chimie SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9608885A priority Critical patent/FR2751326B1/en
Application filed by Rhone Poulenc Chimie SA filed Critical Rhone Poulenc Chimie SA
Priority to US09/230,044 priority patent/US6191309B1/en
Priority to AT97934576T priority patent/ATE224866T1/en
Priority to PT97934576T priority patent/PT912492E/en
Priority to DE69715864T priority patent/DE69715864T2/en
Priority to JP10505696A priority patent/JP2000514449A/en
Priority to EP97934576A priority patent/EP0912492B1/en
Priority to ES97934576T priority patent/ES2185034T3/en
Priority to AU37733/97A priority patent/AU3773397A/en
Priority to PCT/FR1997/001323 priority patent/WO1998002409A1/en
Priority to CN97197505A priority patent/CN1228761A/en
Publication of FR2751326A1 publication Critical patent/FR2751326A1/en
Application granted granted Critical
Publication of FR2751326B1 publication Critical patent/FR2751326B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C07C209/74—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton by halogenation, hydrohalogenation, dehalogenation, or dehydrohalogenation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

The halogenation of a compound of formula (1) or formula (2'), wherein Q is an NH2 group optionally in the form of an addition salt, or an NHCOCH3 group, and X is a halogen atom, using a compound of formula X2, in a solvent selected from an anhydrous halogenated hydrocarbon, a mixture of water and a halogenated hydrocarbon and optionally the compound of formula (1) itself, gives a 2-amino or 2-acetamido trifluoromethylbenzene halogenated in the 5 position of the benzene ring.
FR9608885A 1996-07-16 1996-07-16 PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE Expired - Fee Related FR2751326B1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
FR9608885A FR2751326B1 (en) 1996-07-16 1996-07-16 PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE
AU37733/97A AU3773397A (en) 1996-07-16 1997-07-16 Method for preparing halogenated 2-amino or 2-acetamido trifluoromethylbenzene derivatives
PT97934576T PT912492E (en) 1996-07-16 1997-07-16 METHOD OF PREPARING HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDOTRIFLUOROMETHYLBENZENE
DE69715864T DE69715864T2 (en) 1996-07-16 1997-07-16 METHOD FOR PRODUCING HALOGENED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUORMETHYLBENZENE
JP10505696A JP2000514449A (en) 1996-07-16 1997-07-16 Process for producing halo derivatives of 2-amino- or 2-acetamidotrifluoromethylbenzene
EP97934576A EP0912492B1 (en) 1996-07-16 1997-07-16 Method for preparing halogenated 2-amino or 2-acetamido trifluoromethylbenzene derivatives
US09/230,044 US6191309B1 (en) 1996-07-16 1997-07-16 Method for preparing halogenated 2-amino or 2-acetamido trifluoromethylbenzene derivatives
AT97934576T ATE224866T1 (en) 1996-07-16 1997-07-16 METHOD FOR PRODUCING HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUORMETHYLBENZENE
PCT/FR1997/001323 WO1998002409A1 (en) 1996-07-16 1997-07-16 Method for preparing halogenated 2-amino or 2-acetamido trifluoromethylbenzene derivatives
CN97197505A CN1228761A (en) 1996-07-16 1997-07-16 Method for preparing halogenated 2-amino or 2-acetamido trifluoromethylbenzene
ES97934576T ES2185034T3 (en) 1996-07-16 1997-07-16 PROCEDURE FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDOTRIFLUORME-TILBENCENO.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9608885A FR2751326B1 (en) 1996-07-16 1996-07-16 PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE

Publications (2)

Publication Number Publication Date
FR2751326A1 FR2751326A1 (en) 1998-01-23
FR2751326B1 true FR2751326B1 (en) 1999-08-20

Family

ID=9494102

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9608885A Expired - Fee Related FR2751326B1 (en) 1996-07-16 1996-07-16 PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE

Country Status (11)

Country Link
US (1) US6191309B1 (en)
EP (1) EP0912492B1 (en)
JP (1) JP2000514449A (en)
CN (1) CN1228761A (en)
AT (1) ATE224866T1 (en)
AU (1) AU3773397A (en)
DE (1) DE69715864T2 (en)
ES (1) ES2185034T3 (en)
FR (1) FR2751326B1 (en)
PT (1) PT912492E (en)
WO (1) WO1998002409A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805809B1 (en) * 2000-03-01 2003-08-08 Rhodia Chimie Sa CHLORINATION OF AN ANTINE IN ORTHO IN A FLUORHYDRIAL ENVIRONMENT
CN102993023A (en) * 2011-09-14 2013-03-27 上海工程技术大学 Preparation method of mono-substituted para-chloroaniline

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE637318C (en) * 1935-01-04 1936-10-27 I G Farbenindustrie Akt Ges Process for the preparation of nitro compounds of substituted benzotrifluorides
US2093115A (en) * 1935-04-27 1937-09-14 Gen Aniline Works Inc Aromatic amines which contain the trifluoromethyl group and a process of preparing them
US4008278A (en) * 1975-09-04 1977-02-15 Olin Corporation Preparation of 2-amino-5-halobenzotrifluoride
JPS5718638A (en) * 1980-07-07 1982-01-30 Sagami Chem Res Center Preparation of perfluoroalkyl-substituted benzene derivative
JPS6377844A (en) * 1986-09-18 1988-04-08 Nippon Kayaku Co Ltd Production of p-bromoanilines

Also Published As

Publication number Publication date
DE69715864T2 (en) 2003-05-28
EP0912492A1 (en) 1999-05-06
WO1998002409A1 (en) 1998-01-22
FR2751326A1 (en) 1998-01-23
EP0912492B1 (en) 2002-09-25
DE69715864D1 (en) 2002-10-31
PT912492E (en) 2003-02-28
US6191309B1 (en) 2001-02-20
JP2000514449A (en) 2000-10-31
CN1228761A (en) 1999-09-15
ATE224866T1 (en) 2002-10-15
AU3773397A (en) 1998-02-09
ES2185034T3 (en) 2003-04-16

Similar Documents

Publication Publication Date Title
ES2162871T3 (en) OXINDOL DERIVATIVES REPLACED IN POSITION 3 OF BIOLOGICAL ACTION, USED AS ANTI-ANGIOGENIC AGENTS.
CY1109604T1 (en) BETA-2ADRENERGIC RECEPTOR ANTAGONISTS
ES2097174T3 (en) DERIVATIVES OF 2-CICLOHEXAN-1-IL AMINA.
ES2107118T3 (en) PROCEDURE FOR THE PREPARATION OF QUATERNARY DIESTERS.
DK1177176T3 (en) Triarylic acid derivatives as PPAR receptor ligands
GB9514473D0 (en) Chemical compounds
EA200000393A1 (en) CHEMICAL COMPOUNDS
MX9302214A (en) DERIVATIVES OF TAXOL AND PROCESS FOR ITS PREPARATION
DK0380063T3 (en) 1,2-Cyclohexylaminoarylamides for use as analgesics
DK0464465T3 (en) Substituted aminoalkylbiphenyl derivatives, antimycotic preparations containing these derivatives and intermediates for their preparation
ES2053439T3 (en) A PROCEDURE FOR THE PREPARATION OF A COMPOUND THAT HAS USEFUL PHARMACOLOGICAL PROPERTIES.
MX9300552A (en) ETHANOLAMINE DERIVATIVES
NZ503912A (en) Piperidinylaminomethyl trifluoromethyl cyclic ether compounds and their use as substance P antagonists
DK351788A (en) TETRAHYDROISOQUINOLIN-2-YLD DERIVATIVES OF CARBOXYLIC ACIDS AS THROMBOXAN-A2 ANTAGONISTS
HUP0202881A2 (en) Antistatic agent
FR2751326B1 (en) PROCESS FOR THE PREPARATION OF HALOGENATED DERIVATIVES OF 2-AMINO OR 2-ACETAMIDO TRIFLUOROMETHYLBENZENE
ES2104892T3 (en) PROCEDURE FOR THE PREPARATION OF 2-AMINO-6-CHLOROPURINE AND ITS DERIVATIVES.
DK0925295T3 (en) Derivatives of N-benzenesulfonyl-L-proline as antagonists of the receptor B2 for bradykinin
ES2000524A6 (en) Oxa-, thia- and diazabicycloalkane derivatives, process for their preparation and their use as pharmaceuticals.
PT96757A (en) PROCESS FOR THE PREPARATION OF INDOOR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS
ES2084733T3 (en) NEW BETA-GALACTOSIDASE SUBSTRATES FOR CEDIA ANALYSIS.
EA199800693A1 (en) NITROGEN COMPOUNDS WITH ANTI-FIBER ACTIVITY, INTENDED FOR HUMAN AND ANIMALS
FR2724645B1 (en) PROCESS FOR OBTAINING CUBIC BN BY A SOLVOTHERMAL METHOD WITH THE USE OF HYDRAZINE AS A SOLVENT
ES2082703B1 (en) NEW DERIVATIVES OF CYCLOPROPIL, PROCEDURES FOR ITS PREPARATION AND APPLICATIONS.
DK428087A (en) Dihydropyridine-5-phosphonic acid CYCLOPROPYLENESTER

Legal Events

Date Code Title Description
ST Notification of lapse