FR2742051B1 - USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES - Google Patents

USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES

Info

Publication number
FR2742051B1
FR2742051B1 FR9514393A FR9514393A FR2742051B1 FR 2742051 B1 FR2742051 B1 FR 2742051B1 FR 9514393 A FR9514393 A FR 9514393A FR 9514393 A FR9514393 A FR 9514393A FR 2742051 B1 FR2742051 B1 FR 2742051B1
Authority
FR
France
Prior art keywords
neuropathies
affinity
prevention
compounds
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9514393A
Other languages
French (fr)
Other versions
FR2742051A1 (en
Inventor
Jesus Benavides
Badia Ferzaz
Pascal George
Patrick Pasau
Jonathan Frost
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9514393A priority Critical patent/FR2742051B1/en
Publication of FR2742051A1 publication Critical patent/FR2742051A1/en
Application granted granted Critical
Publication of FR2742051B1 publication Critical patent/FR2742051B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR9514393A 1995-12-06 1995-12-06 USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES Expired - Fee Related FR2742051B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR9514393A FR2742051B1 (en) 1995-12-06 1995-12-06 USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9514393A FR2742051B1 (en) 1995-12-06 1995-12-06 USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES

Publications (2)

Publication Number Publication Date
FR2742051A1 FR2742051A1 (en) 1997-06-13
FR2742051B1 true FR2742051B1 (en) 1998-02-06

Family

ID=9485180

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9514393A Expired - Fee Related FR2742051B1 (en) 1995-12-06 1995-12-06 USE OF COMPOUNDS HAVING AFFINITY FOR THE (3H) IFENPRODIL BINDING SITE FOR THE MANUFACTURE OF DRUGS USEFUL IN THE PREVENTION AND TREATMENT OF NEUROPATHIES

Country Status (1)

Country Link
FR (1) FR2742051B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2469023C1 (en) * 2011-06-22 2012-12-10 Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН) 4-[2-(4-benzylpiperidin-1-yl)-hydroxypropyl] phenol uniformly labelled with tritium

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2661372A (en) * 1953-12-01 Pharmacologically valuable stereo
FR1165845A (en) * 1955-05-28 1958-10-29 Philips Nv Secondary amines bearing substituents and their preparation
FR2641276B1 (en) * 1988-12-30 1991-07-12 Sanofi Sa BENZENE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IE912759A1 (en) * 1990-08-06 1992-02-12 Smith Kline French Lab Compounds
EP0543919B1 (en) * 1990-08-13 1996-04-10 G.D. Searle & Co. Use of heterocyclic amino-alcohol compounds in the manufacture of a medicament for treatment of cns diseases
FR2678269B1 (en) * 1991-06-27 1995-01-13 Synthelabo DERIVATIVES OF 1- (4-CHLOROPHENYL) -2- [4- (2-PHENYLETHYL) PIPERIDIN-1-YL] ETHANOL, THEIR APPLICATION AND THEIR PREPARATION IN THERAPEUTICS.
HU211019B (en) * 1991-12-02 1995-09-28 Richter Gedeon Vegyeszet Process for producing new 1,2,3,6-tetrahydropyridine and piperidine derivatives substituted with n-(hydroxylalkyl) group and compositions comprising such compounds
FR2688504B1 (en) * 1992-03-13 1995-05-05 Synthelabo DERIVATIVES OF 2- (PIPERIDIN-1-YL) ETHANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
ES2060547B1 (en) * 1992-06-04 1995-06-16 Ferrer Int IMPROVEMENTS IN THE PURPOSE OF THE INVENTION PATENT N / 9201158 THAT REFERS TO "PROCEDURE FOR OBTAINING NEW DERIVATIVES OF 4-BENCILPIPERIDINE".
FR2696741B1 (en) * 1992-10-12 1994-11-25 Synthelabo 1- (4-Chlorophenyl) -2- [4 - [(4-fluorophenyl) methyl] piperidin-1-yl] ethanol derivatives, their preparation and their therapeutic use.
FR2699534B1 (en) * 1992-12-21 1995-02-03 Synthelabo Alpha-thienyl-piperidine-1-ethanol derivatives, their preparation and their therapeutic use.
FR2706894A1 (en) * 1993-06-22 1994-12-30 Synthelabo N-Phenyl-N-(piperidinoalkyl)arylamide derivatives, their preparation and their application in therapeutics
TW281670B (en) * 1993-09-02 1996-07-21 Hoffmann La Roche
FR2722989B1 (en) * 1994-07-29 1997-05-30 Synthelabo USE OF IFENPRODIL AND ITS ENANTIOMERS FOR THE PREPARATION OF MEDICINES USEFUL IN THE TREATMENT OF PERIPHERAL NEUROPATHIES AND CENTRAL NEURODEGENERATIVE DISEASES

Also Published As

Publication number Publication date
FR2742051A1 (en) 1997-06-13

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ST Notification of lapse