FR2717473B1 - Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments. - Google Patents

Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments.

Info

Publication number
FR2717473B1
FR2717473B1 FR9403073A FR9403073A FR2717473B1 FR 2717473 B1 FR2717473 B1 FR 2717473B1 FR 9403073 A FR9403073 A FR 9403073A FR 9403073 A FR9403073 A FR 9403073A FR 2717473 B1 FR2717473 B1 FR 2717473B1
Authority
FR
France
Prior art keywords
cyclopropylacetonitrile
medicaments
derivatives
preparation
cyclopropylacetonitrile derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9403073A
Other languages
French (fr)
Other versions
FR2717473A1 (en
Inventor
Jordi Corbera-Arjona
Jordi Frigola-Constansa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9403073A priority Critical patent/FR2717473B1/en
Application filed by Individual filed Critical Individual
Priority to JP7523852A priority patent/JPH08510476A/en
Priority to AU21087/95A priority patent/AU2108795A/en
Priority to KR1019950705080A priority patent/KR960702430A/en
Priority to PCT/EP1995/000985 priority patent/WO1995025087A1/en
Priority to EP95913879A priority patent/EP0699182A1/en
Priority to CA002162916A priority patent/CA2162916A1/en
Priority to ES09500565A priority patent/ES2116878B1/en
Priority to ZA952161A priority patent/ZA952161B/en
Publication of FR2717473A1 publication Critical patent/FR2717473A1/en
Application granted granted Critical
Publication of FR2717473B1 publication Critical patent/FR2717473B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
FR9403073A 1994-03-16 1994-03-16 Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments. Expired - Fee Related FR2717473B1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FR9403073A FR2717473B1 (en) 1994-03-16 1994-03-16 Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments.
AU21087/95A AU2108795A (en) 1994-03-16 1995-03-15 Cyclopropylacetonitrile derivatives, preparation thereof and use thereof as drugs
KR1019950705080A KR960702430A (en) 1994-03-16 1995-03-15 Cyclopropyl acetonitrile derivatives, methods for their preparation and their use as medicaments (CYCLOPROPYLACETONITRILE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS DRUGS)
PCT/EP1995/000985 WO1995025087A1 (en) 1994-03-16 1995-03-15 Cyclopropylacetonitrile derivatives, preparation thereof and use thereof as drugs
JP7523852A JPH08510476A (en) 1994-03-16 1995-03-15 Cyclopropylacetonitrile derivative, its production method and its use as a medicine
EP95913879A EP0699182A1 (en) 1994-03-16 1995-03-15 Cyclopropylacetonitrile derivatives, preparation thereof and use thereof as drugs
CA002162916A CA2162916A1 (en) 1994-03-16 1995-03-15 Cyclopropylacetonitrile derivatives, preparation thereof and use thereof as drugs
ES09500565A ES2116878B1 (en) 1994-03-16 1995-03-16 CYCLOPROPYLACETONITRILE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICINES.
ZA952161A ZA952161B (en) 1994-03-16 1995-03-23 Cyclopropylacetonitrile derivatives their preparation and their application as medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9403073A FR2717473B1 (en) 1994-03-16 1994-03-16 Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments.

Publications (2)

Publication Number Publication Date
FR2717473A1 FR2717473A1 (en) 1995-09-22
FR2717473B1 true FR2717473B1 (en) 1996-06-28

Family

ID=9461104

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9403073A Expired - Fee Related FR2717473B1 (en) 1994-03-16 1994-03-16 Cyclopropylacetonitrile derivatives, their preparation and their use as medicaments.

Country Status (9)

Country Link
EP (1) EP0699182A1 (en)
JP (1) JPH08510476A (en)
KR (1) KR960702430A (en)
AU (1) AU2108795A (en)
CA (1) CA2162916A1 (en)
ES (1) ES2116878B1 (en)
FR (1) FR2717473B1 (en)
WO (1) WO1995025087A1 (en)
ZA (1) ZA952161B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2435824A (en) * 2006-03-09 2007-09-12 Esteve Labor Dr Use of nitrile compounds in the treatment of food related and other disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4612329A (en) * 1984-10-17 1986-09-16 Hokuriku Pharmaceutical Co., Ltd. Pharmaceutical alpha-aminoalkyl-alpha-alkylphenylacetonitriles
DE3603032A1 (en) * 1986-01-31 1987-08-06 Basf Ag BASICLY SUBSTITUTED PHENYL ACETONITRILES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM
DE3642331A1 (en) * 1986-12-11 1988-06-23 Basf Ag BASICLY SUBSTITUTED PHENYL ACETONITRILES, THEIR PRODUCTION AND THE MEDICINAL PRODUCTS CONTAINING THEM

Also Published As

Publication number Publication date
CA2162916A1 (en) 1995-09-21
JPH08510476A (en) 1996-11-05
EP0699182A1 (en) 1996-03-06
KR960702430A (en) 1996-04-27
ES2116878A1 (en) 1998-07-16
ES2116878B1 (en) 1999-09-16
WO1995025087A1 (en) 1995-09-21
AU2108795A (en) 1995-10-03
ZA952161B (en) 1995-12-14
FR2717473A1 (en) 1995-09-22

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Legal Events

Date Code Title Description
ST Notification of lapse