FR2700540B1 - alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique. - Google Patents

alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique.

Info

Publication number
FR2700540B1
FR2700540B1 FR9300331A FR9300331A FR2700540B1 FR 2700540 B1 FR2700540 B1 FR 2700540B1 FR 9300331 A FR9300331 A FR 9300331A FR 9300331 A FR9300331 A FR 9300331A FR 2700540 B1 FR2700540 B1 FR 2700540B1
Authority
FR
France
Prior art keywords
arylcycloalkylalkylamides
tryptophyl
ligands
therapy
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9300331A
Other languages
English (en)
Other versions
FR2700540A1 (fr
Inventor
Yves Pascal
Pierre Calvet Alain
Agnes Grouhel
Jean-Louis Junien
Louis Pascaud Xavier Bernard
Joseph Roman Francois
Joseph Wettstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IRJ
Original Assignee
IRJ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IRJ filed Critical IRJ
Priority to FR9300331A priority Critical patent/FR2700540B1/fr
Priority to PCT/FR1994/000033 priority patent/WO1994015917A1/fr
Priority to AU58615/94A priority patent/AU5861594A/en
Publication of FR2700540A1 publication Critical patent/FR2700540A1/fr
Application granted granted Critical
Publication of FR2700540B1 publication Critical patent/FR2700540B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR9300331A 1993-01-15 1993-01-15 alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique. Expired - Fee Related FR2700540B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9300331A FR2700540B1 (fr) 1993-01-15 1993-01-15 alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique.
PCT/FR1994/000033 WO1994015917A1 (fr) 1993-01-15 1994-01-11 Alpha-methyl-(r)-tryptophyl-arylcycloalkylalkylamides comme ligands aux recepteurs des gastrines
AU58615/94A AU5861594A (en) 1993-01-15 1994-01-11 Alpha-methyl-(r)-tryptophyl-arylcycloalkylalkylamides as ligands for gastrin receptors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9300331A FR2700540B1 (fr) 1993-01-15 1993-01-15 alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique.

Publications (2)

Publication Number Publication Date
FR2700540A1 FR2700540A1 (fr) 1994-07-22
FR2700540B1 true FR2700540B1 (fr) 1995-02-17

Family

ID=9443050

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9300331A Expired - Fee Related FR2700540B1 (fr) 1993-01-15 1993-01-15 alpha-méthyl-(R)-tryptophyl-arylcycloalkylalkylamides ligands aux récepteurs des gastrines, leur préparation et leur utilisation en thérapeutique.

Country Status (3)

Country Link
AU (1) AU5861594A (fr)
FR (1) FR2700540B1 (fr)
WO (1) WO1994015917A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5244915A (en) * 1990-08-31 1993-09-14 Warner-Lambert Company Amico acid derivatives cyclized at the c-terminal
AU5667900A (en) 1999-06-30 2001-01-22 Prescient Neuropharma Inc. 2-aminoindane analogs
US6699909B1 (en) * 1999-07-02 2004-03-02 Prescient Neuropharma Inc. Aminoindanes
CA2600833A1 (fr) * 2005-03-30 2006-10-05 Merck & Co., Inc. Composes antagonistes du recepteur du glucagon, compositions renfermant de tels composes et methodes d'utilisation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ234264A (en) * 1989-06-29 1993-05-26 Warner Lambert Co N-substituted cycloalkyl and polycycloalkyl alpha-substituted trp-phe- and phenethylamine derivatives, and pharmaceutical compositions
US5244915A (en) * 1990-08-31 1993-09-14 Warner-Lambert Company Amico acid derivatives cyclized at the c-terminal

Also Published As

Publication number Publication date
AU5861594A (en) 1994-08-15
WO1994015917A1 (fr) 1994-07-21
FR2700540A1 (fr) 1994-07-22

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Legal Events

Date Code Title Description
ST Notification of lapse