FR2694701A1 - Zeolite cages loaded with pharmaceutical and contg. magnetic rod - allowing in-viro targetting and rotation by external magnetic field, esp. to clear vascular obstructions. - Google Patents

Abstract

Zeolite cages for transporting medicines (I) contain a magnetised rod, made of cobalt or some other metal which can produce a permanent magnet, inside the zeolite or sodalite cage, the other orifices being loaded with (I). Partic. the rod has at least one sharp end, allowing it to cut into flesh and fat (in the same way as a circular saw) inside blood vessels in a human or animal body. USE/ADVANTAGE - By rotating the cages inside a blood vessel, fats which obstruct arteries can be eliminated. In this case (I) is partic. an anaesthetic. The magnetic rod allows the (I)-loaded cages to be directed (by an external magnetic field) to exactly the required place in the body, where (I) is released with max effect.

Description

 The present invention relates to the exploitation of zeolites which are materials made up of oxygen, aluminum or silicon atoms. They have the particularity of being provided with holes of the approximate diameter of the molecule; they have therefore been called "molecular sieves".

 This same material, assembled in zeolite cages, doped with magnetic materials (iron, cobalt or other ferrous metals), and loaded with remedies, can serve as a "molecular vehicle" and transport remedies to the exact place where their effectiveness is most large, using vessels, such as arteries.

 Driven and supplied with energy from the outside, it can behave like a circular saw in order to cut fatty deposits inside the arteries.

 Certain means are used to break down the fatty tissues which block the arteries and often cause the death of the patient; treatments for these conditions are similar to surgery, which is often difficult for the patient to bear.

 The treatments generally used for the majority of the affections are done by remedies swallowed by oral way or by bite, but these have the disadvantage of invading all the economy, and of provoking reactions often harmful in the organs which were not not targeted.

 In the "molecular vehicle" device, it is this material, an assembly of zeolite cages, which makes it possible to boost the cage so as to make it sensitive to the magnetic field, and to charge it with remedies intended to be conveyed in microscopic sub- sailors, drowned in blood or moods, to reach the sick point.

Equipped with cutting edges, these cages in a state of rotation, are similar to circular saws, for cutting, for example, the grease that clogs the arteries.

 The devices which are the subject of the present invention use minerals which are natural zeolites and obtained from the immense deposits which exist in the world.

 Because of their extreme thinness, zeolite cages have the ability to make their way between white or red blood cells, as well as microorganisms contained in the vessels #u human body, due to the rotation on themselves which is printed to them.

 This device is characterized by the introduction of a bar magnetized with cobalt, or any other metal, which can behave as a permanent magnet, in a zeolite or sodalite cage; the other openings are loaded with remedies.

 According to an advantageous embodiment, this bar can be sharp - at its (or its) end (s) allowing it to cut in the flesh or fat, like a circular saw embedded in a blood vessel of the human body or an animal.

 These zeolite cages can be piloted from the outside, in order to lead them exactly to the sick place, so that they release there their load of remedies; they can be stopped at this location and maintained by stopping the steering and rotation; or by a permanent magnet.

 These "cages" are assimilated to a rotor receiving the energy in magnetic form pulsed by the electromagnets; the field is rotating either in one direction or in the other; the zeolite cage can therefore rotate either clockwise or counterclockwise.

 The speed of rotation of the zeolite cages is determined by the speed of a miniature continuous motor with a cage pierced by a window secured to it. The passage of the window alternately lights up photo-diodes whose resistance variation triggers thyristors which, one after the other, generate magnetic pulses when they are coupled with the coils of the electromagnets.

 The same material is always used, this time grouped into cages (by nature). This vehicle, a rotor, which is embedded in a blood vessel, or in certain moods, is driven from the outside by a rotating magnetic field.

 The rotor (zeolite or sodalite cage) rotates inside the blood vessel at field speed, with some slippage.

Other characteristics and advantages of the present invention will emerge from the description which follows, given with reference to the appended drawings
- Figure 1 shows a cage of natural zeolite (Faujasite). It is intended to convey the remedies exactly where they are most effective. To this end, this cage contains, in accordance with the invention, on the one hand the desired drug housed in the molecular sieve 31 and, on the other hand, a microscopic rod of magnetized cobalt or of a metal, permanent magnet 30
- Figure 2 shows a sodalite cage whose role is to cut fat or tissue using the two terminations of the transverse bar of magnetized cobalt. These two endings are cut in the form of a "scalpel drill" 32, 33. This same molecular sieve can also be loaded with remedies and, in this particular case, with anesthetics
- Figures 3 to 6 schematically show the apparatus and accessories necessary for the implementation of the device of the invention.

 Indeed, the control and rotation of the "rotors" (zeolite cages) using rotating magnetic fields are carried out from electrical signals translated into magnetic signals by a probe (Figure 4) connected to the generator (Figure 3) electrical signals, via cable 39; The rotor speed is read at 34; the variation of this speed is done by the lever 35 the direction of rotation is obtained at 36; the button 37 corresponds to "on-off" associated with the indicator lamp 38.

 The generation of the electrical signals is carried out using a miniature electric motor 46 which drives a cage 45 provided with a window which illuminates one after the other three photo-diodes 43 arranged at 1200 one of the 'other.

 The variation in resistance of these polarizes the trigger of the thyristors 47 which supply powerful electromagnets 40, 41, 42 disposed approximately 10 cm from the organ of the patient to be treated.

 The direction of rotation is determined by the polarity applied to the terminals of the DC motor; the speed of the rotating field determines the speed of the zeolite cages.

Claims (3)

 1. Zeolite cages carrying remedies, characterized in that they contain a magnetic bar (30) of cobalt, or any other metal which may behave as a permanent magnet, in the zeolite (31) or sodalite cage, the other orifices being charged remedies.  2. Zeolite cages according to claim 1, characterized in that they comprise a cutting bar, at its (or its) end (s) (32, 33) allowing it to cut into the flesh, or fat, such as a saw circular embedded in a blood vessel of the human body or animal.  3. Zeolite cages according to claim 1 or 2, characterized in that they can be controlled from the outside in order to lead them exactly to the sick place, so that they release there their load of remedies, which can be stopped at this point, and maintained by stopping piloting and rotation or, by a permanent magnet, these cages being assimilated to a rotor receiving energy in magnetic form pulsed by electromagnets (40, 41, 42), the field being rotating either in one direction or in the other, the zeolite cage therefore being able to rotate either clockwise or counterclockwise, the speed of rotation of the zeolite cages being determined by the speed d '' a miniature continuous motor (46), a cage (45) pierced with a window and integral with it, the passage of the window alternately illuminating photo-diodes (43) whose variation in resistance triggers thyristors (47 ) who, some after ès the others, are generators of magnetic impulses, when they are coupled with the coils of the electromagnets (40, 41, 42).