FR2658196B1 - N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM. - Google Patents

N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Info

Publication number
FR2658196B1
FR2658196B1 FR9001553A FR9001553A FR2658196B1 FR 2658196 B1 FR2658196 B1 FR 2658196B1 FR 9001553 A FR9001553 A FR 9001553A FR 9001553 A FR9001553 A FR 9001553A FR 2658196 B1 FR2658196 B1 FR 2658196B1
Authority
FR
France
Prior art keywords
glycinamides
acetamido
phenyl
preparation
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9001553A
Other languages
French (fr)
Other versions
FR2658196A1 (en
Inventor
Bourzat Jean-Dominique
Capet Marc
Cotrel Claude
Guyon Claude
Manfre Franco
Roussel Gerard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Priority to FR9001553A priority Critical patent/FR2658196B1/en
Priority to FR9011916A priority patent/FR2667319B2/en
Priority to FR9012594A priority patent/FR2667863B2/en
Priority to ES91903956T priority patent/ES2052372T3/en
Priority to US07/867,690 priority patent/US5382590A/en
Priority to EP91903956A priority patent/EP0514442B1/en
Priority to AU73295/91A priority patent/AU639081B2/en
Priority to PCT/FR1991/000087 priority patent/WO1991012264A1/en
Priority to KR1019920701912A priority patent/KR927003625A/en
Priority to DK91903956.0T priority patent/DK0514442T3/en
Priority to JP91504069A priority patent/JPH05506643A/en
Priority to DE69101835T priority patent/DE69101835T2/en
Priority to CA002072981A priority patent/CA2072981A1/en
Priority to HU922585A priority patent/HUT61575A/en
Priority to AT9191903956T priority patent/ATE104989T1/en
Priority to IL97180A priority patent/IL97180A0/en
Priority to ZA91946A priority patent/ZA91946B/en
Priority to PT96712A priority patent/PT96712A/en
Priority to IE042891A priority patent/IE910428A1/en
Priority to NZ237052A priority patent/NZ237052A/en
Publication of FR2658196A1 publication Critical patent/FR2658196A1/en
Application granted granted Critical
Publication of FR2658196B1 publication Critical patent/FR2658196B1/en
Priority to NO923079A priority patent/NO923079D0/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/19—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/20—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/21—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C205/22—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups and hydroxy groups bound to carbon atoms of six-membered aromatic rings having nitro groups and hydroxy groups bound to carbon atoms of the same non-condensed six-membered aromatic ring having one nitro groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/58—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/59—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C205/60—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms in ortho-position to the carboxyl group, e.g. nitro-salicylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
FR9001553A 1990-02-09 1990-02-09 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM. Expired - Lifetime FR2658196B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR9001553A FR2658196B1 (en) 1990-02-09 1990-02-09 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
FR9011916A FR2667319B2 (en) 1990-02-09 1990-09-27 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
FR9012594A FR2667863B2 (en) 1990-02-09 1990-10-12 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.
AT9191903956T ATE104989T1 (en) 1990-02-09 1991-02-06 N-PHENYL-N-ACETAMIDOGLYCINAMIDES, THEIR PREPARATION AND MEDICATIONS THEY CONTAIN.
EP91903956A EP0514442B1 (en) 1990-02-09 1991-02-06 N-phenyl n-acetamido glycinamides, preparation method and drugs containing them
AU73295/91A AU639081B2 (en) 1990-02-09 1991-02-06 N-phenyl n-acetamido glycinamides, preparation method and drugs containing them
PCT/FR1991/000087 WO1991012264A1 (en) 1990-02-09 1991-02-06 N-phenyl n-acetamido glycinamides, preparation method and drugs containing them
KR1019920701912A KR927003625A (en) 1990-02-09 1991-02-06 N-phenyl-N-acetamido glycinamide, preparation method and drug containing them
DK91903956.0T DK0514442T3 (en) 1990-02-09 1991-02-06 N-Phenyl-N-acetamidoglycinamides, their preparation and drugs containing them
JP91504069A JPH05506643A (en) 1990-02-09 1991-02-06 N-phenyl-N-acetamidoglycinamides, their production and drugs containing them
ES91903956T ES2052372T3 (en) 1990-02-09 1991-02-06 N-PHENYL N-ACETAMIDE GLYCINAMIDES ITS PREPARATION AND THE MEDICINES CONTAINING THEM.
CA002072981A CA2072981A1 (en) 1990-02-09 1991-02-06 N-phenyl n-acetamido glycinamides, their preparation and drugs holding same
HU922585A HUT61575A (en) 1990-02-09 1991-02-06 Process for producing n-acetamido-n-phenyl glycineamide derivatives and pharmaceutical compositions comprising same
US07/867,690 US5382590A (en) 1990-02-09 1991-02-06 N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them
DE69101835T DE69101835T2 (en) 1990-02-09 1991-02-06 N-PHENYL-N-ACETAMIDOGLYCINAMIDES, THEIR PRODUCTION AND MEDICINAL PRODUCTS CONTAINING THEM.
IL97180A IL97180A0 (en) 1990-02-09 1991-02-07 N-phenyl-n-acetamidoglycinamides,their preparation and medicaments containing them
ZA91946A ZA91946B (en) 1990-02-09 1991-02-08 N-phenyl-n-acetamidoglycinamides,their preparation and medicaments containing them
PT96712A PT96712A (en) 1990-02-09 1991-02-08 PREPARATION OF N-PHENYL-N-ACETAMIDE-GLYCINAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IE042891A IE910428A1 (en) 1990-02-09 1991-02-08 N-phenyl-n-acetamidoglycinamides, their preparation and¹medicaments containing them
NZ237052A NZ237052A (en) 1990-02-09 1991-02-08 N-phenyl-n-acetamidoglycinamide derivatives and pharmaceutical compositions
NO923079A NO923079D0 (en) 1990-02-09 1992-08-05 N-PHENYL-N-ACETAMIDOGLYCINAMIDES, THEIR PREPARATION AND MEDICINES CONTAINING THE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9001553A FR2658196B1 (en) 1990-02-09 1990-02-09 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
FR2658196A1 FR2658196A1 (en) 1991-08-16
FR2658196B1 true FR2658196B1 (en) 1992-04-24

Family

ID=9393558

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9001553A Expired - Lifetime FR2658196B1 (en) 1990-02-09 1990-02-09 N-PHENYL N-ACETAMIDO GLYCINAMIDES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Country Status (2)

Country Link
FR (1) FR2658196B1 (en)
ZA (1) ZA91946B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3423420A1 (en) * 1984-06-26 1986-01-02 Hoechst Ag, 6230 Frankfurt METHOD FOR DETECTING STEP LOSES IN STEPPER MOTOR-DRIVEN ACTUATORS
EP0175498A2 (en) * 1984-08-23 1986-03-26 The Administrators Of The Tulane University Educational Fund Peptides, their use in medicine and methods for their preparation

Also Published As

Publication number Publication date
FR2658196A1 (en) 1991-08-16
ZA91946B (en) 1991-11-27

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Legal Events

Date Code Title Description
ST Notification of lapse