FR2652353B1 - NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS. - Google Patents

NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS.

Info

Publication number
FR2652353B1
FR2652353B1 FR8912452A FR8912452A FR2652353B1 FR 2652353 B1 FR2652353 B1 FR 2652353B1 FR 8912452 A FR8912452 A FR 8912452A FR 8912452 A FR8912452 A FR 8912452A FR 2652353 B1 FR2652353 B1 FR 2652353B1
Authority
FR
France
Prior art keywords
thioxylosides
therapeutics
beta
preparation process
novel benzopyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8912452A
Other languages
French (fr)
Other versions
FR2652353A1 (en
Inventor
Soth Samreth
Veronique Barberousse
Patrice Renaut
Francois Bellamy
Jean Millet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fournier Industrie et Sante SAS
Original Assignee
Fournier Industrie et Sante SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8912452A priority Critical patent/FR2652353B1/en
Application filed by Fournier Industrie et Sante SAS filed Critical Fournier Industrie et Sante SAS
Priority to ES90402403T priority patent/ES2066165T3/en
Priority to AT90402403T priority patent/ATE113956T1/en
Priority to DK90402403.1T priority patent/DK0421829T3/en
Priority to DE69014064T priority patent/DE69014064T2/en
Priority to EP90402403A priority patent/EP0421829B1/en
Priority to CA002024476A priority patent/CA2024476C/en
Priority to IL9558290A priority patent/IL95582A/en
Priority to US07/579,702 priority patent/US5169838A/en
Priority to AU62531/90A priority patent/AU631456B2/en
Priority to FI904614A priority patent/FI100183B/en
Priority to NO904088A priority patent/NO172987C/en
Priority to PT95369A priority patent/PT95369B/en
Priority to YU178790A priority patent/YU47867B/en
Priority to NZ245783A priority patent/NZ245783A/en
Priority to UA4831306A priority patent/UA13476A/en
Priority to HU906005A priority patent/HU207867B/en
Priority to IE341490A priority patent/IE65092B1/en
Priority to DD90344131A priority patent/DD297649A5/en
Priority to JP2253983A priority patent/JPH07103147B2/en
Priority to KR1019900014981A priority patent/KR0142670B1/en
Priority to ZA907567A priority patent/ZA907567B/en
Priority to SU904831306A priority patent/RU1838323C/en
Priority to CN90107856A priority patent/CN1027268C/en
Priority to SK4638-90A priority patent/SK463890A3/en
Publication of FR2652353A1 publication Critical patent/FR2652353A1/en
Priority to AU25397/92A priority patent/AU642829B2/en
Priority to HRP-1787/90A priority patent/HRP920811B1/en
Application granted granted Critical
Publication of FR2652353B1 publication Critical patent/FR2652353B1/en
Priority to GR950400222T priority patent/GR3014966T3/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/07Benzo[b]pyran-4-ones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06Benzopyran radicals
    • C07H17/065Benzo[b]pyrans
    • C07H17/075Benzo[b]pyran-2-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8912452A 1989-09-22 1989-09-22 NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS. Expired - Fee Related FR2652353B1 (en)

Priority Applications (28)

Application Number Priority Date Filing Date Title
FR8912452A FR2652353B1 (en) 1989-09-22 1989-09-22 NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS.
AT90402403T ATE113956T1 (en) 1989-09-22 1990-08-31 BENZOPYRANONE-BETA-D-THIOXYLOSIDES, PROCESSES FOR THEIR PRODUCTION AND THEIR THERAPEUTIC USE.
DK90402403.1T DK0421829T3 (en) 1989-09-22 1990-08-31 Novel benzopyranone beta-D-thioxylosides, process for their preparation and their therapeutic use
DE69014064T DE69014064T2 (en) 1989-09-22 1990-08-31 Benzopyranone beta-D-thioxyloside, process for its preparation and its therapeutic use.
ES90402403T ES2066165T3 (en) 1989-09-22 1990-08-31 NEW BENZOPYRANONE-BETA-D-THIOXYLOSIDES, ITS PREPARATION PROCEDURE AND ITS USE IN THERAPEUTICS.
EP90402403A EP0421829B1 (en) 1989-09-22 1990-08-31 Benzopyranone-beta-D-thioxylosides, method for their preparation and their use
CA002024476A CA2024476C (en) 1989-09-22 1990-08-31 Benzopyranone-.beta.-d-thioxylosides their method of preparation and their use in therapy
IL9558290A IL95582A (en) 1989-09-22 1990-09-04 Benzopyranone-beta-d-thioxylosides, their method of preparation and pharmaceutical compositions containing them
US07/579,702 US5169838A (en) 1989-09-22 1990-09-10 Benzopyranone-β-D-thioxylosides and their use in therapy
AU62531/90A AU631456B2 (en) 1989-09-22 1990-09-17 Novel benzopyranone-beta-d-thioxylosides, their method of preparation and their use in therapy
FI904614A FI100183B (en) 1989-09-22 1990-09-19 Process and intermediates for the preparation of new, therapeutically useful benzopyranone-D-thioxylosides
NO904088A NO172987C (en) 1989-09-22 1990-09-19 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZOPYRANON-BETA-D-THIOXYLOSIDES
YU178790A YU47867B (en) 1989-09-22 1990-09-20 NEW BENZOPIRANE-2-ON-BETA-D-THIOXYLOSIDES AND PROCEDURE FOR OBTAINING THEM
PT95369A PT95369B (en) 1989-09-22 1990-09-20 PROCESS FOR THE PREPARATION OF NEW BENZOPIRANONE-BETA-D-THIOXYLOSIDES USED IN THERAPEUTICS
NZ245783A NZ245783A (en) 1989-09-22 1990-09-21 Benzopyran and dibenzopyran derivatives as intermediates
HU906005A HU207867B (en) 1989-09-22 1990-09-21 Process for producing benzopiranon-beta-d-thioxylozide derivatives and pharmaceutical compositions containing them
IE341490A IE65092B1 (en) 1989-09-22 1990-09-21 Novel benzopyranone-beta-D-thioxylosides their method of preparation and their use in therapy
DD90344131A DD297649A5 (en) 1989-09-22 1990-09-21 NEW BENZOPYRANONE D-THIOXYLOSIDES, THEIR MANUFACTURING METHOD AND THEIR USE IN THERAPY
JP2253983A JPH07103147B2 (en) 1989-09-22 1990-09-21 Oside compounds containing benzopyranone-β-D-thioxyloside
KR1019900014981A KR0142670B1 (en) 1989-09-22 1990-09-21 Benzopyranone-beta-D-thioxiloside and preparation method thereof
ZA907567A ZA907567B (en) 1989-09-22 1990-09-21 Novel benzopyranone-beta-d-thioxylosides,their method of preparation and their use in therapy
SU904831306A RU1838323C (en) 1989-09-22 1990-09-21 Method of synthesis of benzopyranone--d-thioxylosides
UA4831306A UA13476A (en) 1989-09-22 1990-09-21 METHOD OF PREPARATION OF BENZOPIRANONE-beta-D-THIOXYLOSIDES
CN90107856A CN1027268C (en) 1989-09-22 1990-09-21 Benzopyranone-beta-D-thioxylosides, their method of preparation and their use in therapy
SK4638-90A SK463890A3 (en) 1989-09-22 1990-09-24 Benzopyranone-beta-d-thioxylosides, method for their preparation
AU25397/92A AU642829B2 (en) 1989-09-22 1992-09-28 Benzopyran intermediates
HRP-1787/90A HRP920811B1 (en) 1989-09-22 1992-10-02 New benzophyranone-beta-d-thioxilozides, method for the preparation and use thereof
GR950400222T GR3014966T3 (en) 1989-09-22 1995-02-07 Benzopyranone-beta-d-thioxylosides, method for their preparation and their use.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8912452A FR2652353B1 (en) 1989-09-22 1989-09-22 NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS.

Publications (2)

Publication Number Publication Date
FR2652353A1 FR2652353A1 (en) 1991-03-29
FR2652353B1 true FR2652353B1 (en) 1994-02-11

Family

ID=9385753

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8912452A Expired - Fee Related FR2652353B1 (en) 1989-09-22 1989-09-22 NOVEL BENZOPYRAN-2-ONE-BETA-D-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR USE IN THERAPEUTICS.

Country Status (3)

Country Link
DD (1) DD297649A5 (en)
FR (1) FR2652353B1 (en)
ZA (1) ZA907567B (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034306A1 (en) * 1970-07-10 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof 2 (3,4 Dimethyl-coumarin 7 yl) oxy alkylcarboxylic acid derivatives and process for their preparation
FR2492830A1 (en) * 1980-10-29 1982-04-30 Sori Soc Rech Ind NOVEL COMPOUNDS BELONGING TO THE BENZOYL- AND A-HYDROXYBENZYL-PHENYL-OSIDES FAMILY, PROCESS FOR PREPARING THEM AND THEIR THERAPEUTIC APPLICATION
JPS6013788A (en) * 1983-07-05 1985-01-24 Yamanouchi Pharmaceut Co Ltd Novel coumarin derivative
FR2549476B1 (en) * 1983-07-20 1986-04-25 Rech Ind BENZYL-PHENYL-OSIDES, PROCESS FOR PREPARATION AND THERAPEUTIC USE
US4681954A (en) * 1985-10-07 1987-07-21 Pennwalt Corporation 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes
FR2614893B1 (en) * 1987-05-04 1989-12-22 Fournier Innovation Synergie NOVEL B-D-PHENYL-THIOXYLOSIDES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS

Also Published As

Publication number Publication date
ZA907567B (en) 1991-08-28
DD297649A5 (en) 1992-01-16
FR2652353A1 (en) 1991-03-29

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Legal Events

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ST Notification of lapse
ST Notification of lapse