FR2628740B3 - PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS - Google Patents

PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS

Info

Publication number
FR2628740B3
FR2628740B3 FR8904835A FR8904835A FR2628740B3 FR 2628740 B3 FR2628740 B3 FR 2628740B3 FR 8904835 A FR8904835 A FR 8904835A FR 8904835 A FR8904835 A FR 8904835A FR 2628740 B3 FR2628740 B3 FR 2628740B3
Authority
FR
France
Prior art keywords
phenyl
piperidyl
fluoro
chloro
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8904835A
Other languages
French (fr)
Other versions
FR2628740A3 (en
Inventor
Jonathan Frost
Jean Bertin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8904835A priority Critical patent/FR2628740B3/en
Publication of FR2628740A3 publication Critical patent/FR2628740A3/en
Application granted granted Critical
Publication of FR2628740B3 publication Critical patent/FR2628740B3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8904835A 1989-04-12 1989-04-12 PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS Expired - Lifetime FR2628740B3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8904835A FR2628740B3 (en) 1989-04-12 1989-04-12 PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8904835A FR2628740B3 (en) 1989-04-12 1989-04-12 PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS

Publications (2)

Publication Number Publication Date
FR2628740A3 FR2628740A3 (en) 1989-09-22
FR2628740B3 true FR2628740B3 (en) 1990-01-19

Family

ID=9380638

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8904835A Expired - Lifetime FR2628740B3 (en) 1989-04-12 1989-04-12 PROCESS FOR THE PREPARATION OF (CHLORO-4 PHENYL) -1 (((FLUORO-4 PHENYL) METHYL) -4 PIPERIDYL-1) -2-ETHANOL ENANTIOMERS

Country Status (1)

Country Link
FR (1) FR2628740B3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2694555A1 (en) * 1992-08-05 1994-02-11 Synthelabo 1-(4-chloro 2-hydroxyphenyl) 2-(4-(4-fluorophenyl methyl) piperidine 1-yl) ethanol enantiomer sepn. - by converting racemate to 1-(4-chloro 2-methoxymethyl phenyl) deriv., reacting with 1-phenylethyl isocyanate and sepg. carbamate(s)
FR2696741B1 (en) * 1992-10-12 1994-11-25 Synthelabo 1- (4-Chlorophenyl) -2- [4 - [(4-fluorophenyl) methyl] piperidin-1-yl] ethanol derivatives, their preparation and their therapeutic use.
FR2722497B1 (en) 1994-07-13 1996-08-14 Synthelabo ESTERS OF ALPHA-4-CHLOROPHENYL) -4- (4-FLUOROPHENYL) METHYL) PIPERIDINE-1-ETHANOL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
GB9804885D0 (en) 1998-03-06 1998-04-29 Merck Sharp & Dohme Therapeutic combination
AU2001261360A1 (en) * 2000-05-10 2001-11-20 Alcon, Inc. R-eliprodil for treating glaucoma

Also Published As

Publication number Publication date
FR2628740A3 (en) 1989-09-22

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