FR2608924B1 - THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD - Google Patents

THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD

Info

Publication number
FR2608924B1
FR2608924B1 FR8618297A FR8618297A FR2608924B1 FR 2608924 B1 FR2608924 B1 FR 2608924B1 FR 8618297 A FR8618297 A FR 8618297A FR 8618297 A FR8618297 A FR 8618297A FR 2608924 B1 FR2608924 B1 FR 2608924B1
Authority
FR
France
Prior art keywords
sulfur derivatives
prostaglandins
preparation
compositions containing
therapeutic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8618297A
Other languages
French (fr)
Other versions
FR2608924A1 (en
Inventor
Fernand Dray
Brigitte Vuilliez Le Normand
Alain Gouyette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille
Priority to FR8618297A priority Critical patent/FR2608924B1/en
Priority to PCT/FR1987/000518 priority patent/WO1988005042A1/en
Priority to JP88500743A priority patent/JPH01502117A/en
Priority to EP88900574A priority patent/EP0295284A1/en
Publication of FR2608924A1 publication Critical patent/FR2608924A1/en
Application granted granted Critical
Publication of FR2608924B1 publication Critical patent/FR2608924B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8618297A 1986-12-29 1986-12-29 THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD Expired - Lifetime FR2608924B1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR8618297A FR2608924B1 (en) 1986-12-29 1986-12-29 THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD
PCT/FR1987/000518 WO1988005042A1 (en) 1986-12-29 1987-12-29 Compositions containing sulphur prostaglandines
JP88500743A JPH01502117A (en) 1986-12-29 1987-12-29 Therapeutic compositions containing sulfurized derivatives of prostaglandins, novel sulfurized derivatives and methods for producing them
EP88900574A EP0295284A1 (en) 1986-12-29 1987-12-29 Compositions containing sulphur prostaglandines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8618297A FR2608924B1 (en) 1986-12-29 1986-12-29 THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD

Publications (2)

Publication Number Publication Date
FR2608924A1 FR2608924A1 (en) 1988-07-01
FR2608924B1 true FR2608924B1 (en) 1990-07-20

Family

ID=9342381

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8618297A Expired - Lifetime FR2608924B1 (en) 1986-12-29 1986-12-29 THERAPEUTIC COMPOSITIONS CONTAINING SULFUR DERIVATIVES OF PROSTAGLANDINS, NOVEL SULFUR DERIVATIVES AND THEIR PREPARATION METHOD

Country Status (4)

Country Link
EP (1) EP0295284A1 (en)
JP (1) JPH01502117A (en)
FR (1) FR2608924B1 (en)
WO (1) WO1988005042A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516796A (en) * 1994-03-24 1996-05-14 Kabi Pharmacia Ab Thioprostaglandins and -prostaglandin-like compounds and therapeutic uses thereof
EP1170286A4 (en) 1999-04-09 2003-05-28 Taisho Pharmaceutical Co Ltd Prostaglandin e1 derivatives
AU766900B2 (en) * 1999-09-10 2003-10-23 Fumie Sato Prostaglandin derivatives
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
CN111658628B (en) * 2019-03-08 2022-03-01 中国科学院动物研究所 Application of GLI2 inhibitor and screening method of compound inhibiting GLI2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141914A (en) * 1972-07-24 1979-02-27 American Cyanamid Company Novel 11-deoxy-11-substituted prostaglandins of the E and F series
GB1436378A (en) * 1972-08-21 1976-05-19 American Home Prod Prostaglandin derivatives
GB1545633A (en) * 1975-02-24 1979-05-10 American Cyanamid Co 11-deoxy substituted prostaglandins of the e and f series

Also Published As

Publication number Publication date
EP0295284A1 (en) 1988-12-21
WO1988005042A1 (en) 1988-07-14
FR2608924A1 (en) 1988-07-01
JPH01502117A (en) 1989-07-27

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