FR2606404B2 - NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS - Google Patents

NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS

Info

Publication number
FR2606404B2
FR2606404B2 FR868615788A FR8615788A FR2606404B2 FR 2606404 B2 FR2606404 B2 FR 2606404B2 FR 868615788 A FR868615788 A FR 868615788A FR 8615788 A FR8615788 A FR 8615788A FR 2606404 B2 FR2606404 B2 FR 2606404B2
Authority
FR
France
Prior art keywords
phenylguanidinoacetic
sweeteners
acid
chemical compounds
compounds derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR868615788A
Other languages
French (fr)
Other versions
FR2606404A2 (en
Inventor
Claude Nofre
Jean-Marie Tinti
Farroudja Ouar
Epouse Chatzopoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Claude Bernard Lyon 1 UCBL
Original Assignee
Universite Claude Bernard Lyon 1 UCBL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8605320A external-priority patent/FR2597096B1/en
Application filed by Universite Claude Bernard Lyon 1 UCBL filed Critical Universite Claude Bernard Lyon 1 UCBL
Priority to FR868615788A priority Critical patent/FR2606404B2/en
Priority to US07/021,359 priority patent/US4921939A/en
Priority to DK126787A priority patent/DK126787A/en
Priority to FI871098A priority patent/FI871098A/en
Priority to NZ219593A priority patent/NZ219593A/en
Priority to KR870002290A priority patent/KR870008526A/en
Priority to NO871030A priority patent/NO871030L/en
Priority to PT84480A priority patent/PT84480B/en
Priority to EP87420095A priority patent/EP0241395A3/en
Priority to CN198787102765A priority patent/CN87102765A/en
Priority to AU71326/87A priority patent/AU595598B2/en
Priority to CA000534303A priority patent/CA1301149C/en
Priority to ES8701052A priority patent/ES2005147A6/en
Priority to KR870012503A priority patent/KR880005882A/en
Publication of FR2606404A2 publication Critical patent/FR2606404A2/en
Publication of FR2606404B2 publication Critical patent/FR2606404B2/en
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C311/52—Y being a hetero atom
    • C07C311/64—X and Y being nitrogen atoms, e.g. N-sulfonylguanidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/28—Nitrogen atoms
    • C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04—Four-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
FR868615788A 1985-03-19 1986-11-07 NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS Expired - Lifetime FR2606404B2 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR868615788A FR2606404B2 (en) 1986-04-10 1986-11-07 NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS
US07/021,359 US4921939A (en) 1985-03-19 1987-03-03 Sweetening agents
DK126787A DK126787A (en) 1986-03-13 1987-03-12 SWEETS OF N-PHENYLGUANIDINO ACETIC ACID AND N-PHENYLETHANAMIDINO ACETIC ACID AND PREPARATIONS CONTAINING SUCH SWEETS
FI871098A FI871098A (en) 1986-03-13 1987-03-12 SOETNINGSMEDEL HAERLEDDA FRAON N-PHENYLGUANIDINOETHETICS OCH N-PHENYLETHANAMIDINOETHETICS OCH SAMMANSAETTNINGAR INNEHAOLLANDE DESSA SOETNINGSMEDEL.
NZ219593A NZ219593A (en) 1986-03-13 1987-03-12 High potency sweetening agents
KR870002290A KR870008526A (en) 1986-03-13 1987-03-12 Sweetener and method for producing the same
NO871030A NO871030L (en) 1986-03-13 1987-03-12 SŸTEMIDLER.
PT84480A PT84480B (en) 1986-03-13 1987-03-13 PROCESS FOR THE PREPARATION OF DERIVATIVES OF SUBSTITUTED N-PHENYLGUANIDINOACETIC ACID AND N-PHENYLETHANAMIDINOACETIC ACIDS, WITH SWEATER PROPERTIES
EP87420095A EP0241395A3 (en) 1986-04-10 1987-04-07 Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners
CN198787102765A CN87102765A (en) 1986-04-10 1987-04-09 The preparation method of sweeting agent N-guanidines guanidine-acetic acid and N-phenyl ethanamidine guanidine-acetic acid derivative and the prescription of this class sweeting agent
AU71326/87A AU595598B2 (en) 1986-04-10 1987-04-09 High potency sweetening agents
CA000534303A CA1301149C (en) 1986-04-10 1987-04-09 Sweeteners derived from n-phenylguanidinoacetic and n-phenylethanamidinoacetic acids; compositions containing said sweeteners
ES8701052A ES2005147A6 (en) 1986-04-10 1987-04-10 Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners.
KR870012503A KR880005882A (en) 1986-11-07 1987-11-06 Sweeteners and compositions thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8605320A FR2597096B1 (en) 1986-04-10 1986-04-10 NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS
FR868615788A FR2606404B2 (en) 1986-04-10 1986-11-07 NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS

Publications (2)

Publication Number Publication Date
FR2606404A2 FR2606404A2 (en) 1988-05-13
FR2606404B2 true FR2606404B2 (en) 1991-11-22

Family

ID=26225160

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868615788A Expired - Lifetime FR2606404B2 (en) 1985-03-19 1986-11-07 NOVEL CHEMICAL COMPOUNDS DERIVED FROM PHENYLGUANIDINOACETIC ACID AND THEIR USE AS SWEETENERS

Country Status (1)

Country Link
FR (1) FR2606404B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8283338B2 (en) 2007-11-30 2012-10-09 Kao Corporation GIP secretion inhibitor
US8338389B2 (en) 2009-06-17 2012-12-25 Kao Corporation Agent for preventing or ameliorating obesity

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900740A (en) * 1987-10-02 1990-02-13 The Nutrasweet Company N,N'-disubstituted guanidines containing a carboxyl or a tetrazolyl moiety

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533210A1 (en) * 1982-09-17 1984-03-23 Lyon I Universite Claude SWEETENERS OF SYNTHESIS
FR2579201B1 (en) * 1985-03-19 1987-05-07 Bernard Lyon I Universite Clau IMPROVED CHEMICAL COMPOUNDS, USE AS SWEETENING AGENTS AND COMPOSITIONS CONTAINING SUCH AGENTS
FR2579202B1 (en) * 1985-03-19 1988-04-29 Univ Claude Bernard Lyon NOVEL CHEMICAL COMPOUNDS, USE AS SWEETENERS AND COMPOSITIONS CONTAINING SUCH AGENTS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8283338B2 (en) 2007-11-30 2012-10-09 Kao Corporation GIP secretion inhibitor
US8338389B2 (en) 2009-06-17 2012-12-25 Kao Corporation Agent for preventing or ameliorating obesity

Also Published As

Publication number Publication date
FR2606404A2 (en) 1988-05-13

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