FR2603287A1 - PROCESS FOR THE PREPARATION OF METALLOPROTEIN COMPLEXES AND NEW DERIVATIVES THEREOF - Google Patents

PROCESS FOR THE PREPARATION OF METALLOPROTEIN COMPLEXES AND NEW DERIVATIVES THEREOF

Info

Publication number
FR2603287A1
FR2603287A1 FR8707639A FR8707639A FR2603287A1 FR 2603287 A1 FR2603287 A1 FR 2603287A1 FR 8707639 A FR8707639 A FR 8707639A FR 8707639 A FR8707639 A FR 8707639A FR 2603287 A1 FR2603287 A1 FR 2603287A1
Authority
FR
France
Prior art keywords
preparation
complexes
new derivatives
metalloprotein
metalloprotein complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8707639A
Other languages
French (fr)
Other versions
FR2603287B1 (en
Inventor
Romano Deghenghi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Debiopharm SA
Original Assignee
Debiopharm SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm SA filed Critical Debiopharm SA
Publication of FR2603287A1 publication Critical patent/FR2603287A1/en
Application granted granted Critical
Publication of FR2603287B1 publication Critical patent/FR2603287B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

UN PROCEDE POUR LA PREPARATION DE COMPLEXES DE METALLOPROTEINES BIOLOGIQUEMENT ACTIFS SANS PERTE D'ACTIVITE COMPREND DE PREPARER DE NOUVEAUX COMPLEXES DES APOPROTEINES CORRESPONDANTES, A LES PURIFIER ET A RECONSTITUER L'ACTIVITE BIOLOGIQUE EN AJOUTANT DES METAUX.A PROCESS FOR THE PREPARATION OF BIOLOGICALLY ACTIVE METALLOPROTEIN COMPLEXES WITHOUT LOSS OF ACTIVITY INCLUDES PREPARING NEW COMPLEXES OF THE CORRESPONDING APOPROTEINS, PURIFYING THEM AND RECONSTITUTING BIOLOGICAL ACTIVITY BY ADDING METALS.

FR878707639A 1986-06-02 1987-06-01 PROCESS FOR THE PREPARATION OF METALLOPROTEIN COMPLEXES AND NEW DERIVATIVES THEREOF Expired - Fee Related FR2603287B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8613315A GB2191200B (en) 1986-06-02 1986-06-02 Process for preparing conjugates of metalloproteins and novel derivatives thereof

Publications (2)

Publication Number Publication Date
FR2603287A1 true FR2603287A1 (en) 1988-03-04
FR2603287B1 FR2603287B1 (en) 1991-02-08

Family

ID=10598769

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878707639A Expired - Fee Related FR2603287B1 (en) 1986-06-02 1987-06-01 PROCESS FOR THE PREPARATION OF METALLOPROTEIN COMPLEXES AND NEW DERIVATIVES THEREOF

Country Status (10)

Country Link
JP (1) JPS62292800A (en)
BE (1) BE1002130A3 (en)
CH (1) CH674939A5 (en)
DE (1) DE3718476A1 (en)
DK (1) DK280187A (en)
ES (1) ES2004734A6 (en)
FR (1) FR2603287B1 (en)
GB (1) GB2191200B (en)
IT (1) IT1207805B (en)
NL (1) NL8701254A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1317895B1 (en) * 2000-08-10 2003-07-15 Univ Napoli Federico Ii PSEUDO-METALLOPROTEIN, THEIR PREPARATION AND THEIR USE.
MX354530B (en) * 2013-02-27 2018-02-19 Univ Autonoma Del Estado De Morelos Compositions comprising immp for contributing to the development, growth and improvement of the productive parameters of animals of zootechnical interest, and use of same.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1168150A (en) * 1981-12-18 1984-05-29 The Governors Of The University Of Alberta Targeting conjugates of albumin and therapeutic agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1168150A (en) * 1981-12-18 1984-05-29 The Governors Of The University Of Alberta Targeting conjugates of albumin and therapeutic agents

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 101, no. 14, 1 octobre 1984, page 352, résumé no. 116715v, Columbus, Ohio, US; & CA-A-1 168 150 (UNIVERSITY OF ALBERTA) *
CHEMICAL ABSTRACTS, vol. 102, no. 6, 11 février 1985, page 322, résumé no. 50880g, Columbus, Ohio, US; C.F. MEARES et al.: "Conjugation of antibodies with bifunctional chelating agents: isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions", & ANAL. BIOCHEM. 1984, 142(1), 68-78 *
CHEMICAL ABSTRACTS, vol. 93, no. 7, 18 août 1980, page 96, résumé no. 61591k, Columbus, Ohio, US; K. WONG et al.: "Enhanced anti-inflammatory effect and reduced immunogenicity of bovine liver superoxide dismutase by conjugation with homologous albumin", & AGENTS ACTIONS 1980, 10(3), 231-9 *
CHEMICAL ABSTRACTS, vol. 99, no. 25, 19 décembre 1983, page 38, résumé no. 205790y, Columbus, Ohio, US; L.G. CLELAND et al.: "Superoxide dismutase (SOD) and albumin conjugates with delayed clearance from plasma and body cavities. Is SOD anti-inflammatory", & OXY RADICALS THEIR SCAVENGER SYST., PROC. INT. CONF. SUPEROXIDE DISMUTASE, 3rd 1982 (PUBL 1983). 2, 268-73 *

Also Published As

Publication number Publication date
IT1207805B (en) 1989-06-01
NL8701254A (en) 1988-01-04
GB8613315D0 (en) 1986-07-09
BE1002130A3 (en) 1990-07-24
DK280187D0 (en) 1987-06-01
IT8705187A0 (en) 1987-06-01
GB2191200A (en) 1987-12-09
CH674939A5 (en) 1990-08-15
FR2603287B1 (en) 1991-02-08
GB2191200B (en) 1990-07-11
DK280187A (en) 1987-12-03
JPS62292800A (en) 1987-12-19
ES2004734A6 (en) 1989-02-01
DE3718476A1 (en) 1987-12-03

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Legal Events

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